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Name

Mouse Neuro with Add-on

#1209

Species

Mus musculus

# Genes

1006

# Serial Genes

Description

Focuses on brain cell types and pathways linked to development, function, and disorders. Includes serial add-on genes.

Genes & Annotations

Reactome is a database of signaling and metabolic molecules organized into heirarchical pathways and relationships. Here we show the high level pathways, except 'Disease'. You can click on the pathway to see the full heirarchy and which levels are impacted by genes in the panel.

Annotation	Genes
ABC-family proteins mediated transport Pathway Hierarchies & Genes ABC-family proteins mediated transport (2 genes) Transport of small molecules ABC-family proteins mediated transport 2 genes	Abcc9 Gene Information Basic Information Ensembl ID: ENSMUSG00000030249 Description: ATP-binding cassette%2C sub-family C member 9 [Source:MGI Symbol;Acc:MGI:1352630] Location: 6:142533588-142648041 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell pericyte Other: Potassium Channels ABC-family proteins mediated transport Cardiac conduction Cftr Gene Information Basic Information Ensembl ID: ENSMUSG00000041301 Description: cystic fibrosis transmembrane conductance regulator [Source:MGI Symbol;Acc:MGI:88388] Location: 6:18170686-18322767 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pneumocyte ionocyte Other: Macroautophagy Membrane Trafficking ABC-family proteins mediated transport
ATP-dependent chromatin remodelers Pathway Hierarchies & Genes Formation of the embryonic stem cell BAF (esBAF) complex (2 genes) Chromatin organization ATP-dependent chromatin remodelers SWI/SNF chromatin remodelers Formation of the embryonic stem cell BAF (esBAF) complex 2 genes	Bcl11a Gene Information Basic Information Ensembl ID: ENSMUSG00000000861 Description: BCL11 transcription factor A [Source:MGI Symbol;Acc:MGI:106190] Location: 11:24028056-24124123 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell neuron excitatory neuron dendritic cell myeloid progenitor cell Other: ATP-dependent chromatin remodelers Bcl11b Gene Information Basic Information Ensembl ID: ENSMUSG00000048251 Description: B cell leukemia/lymphoma 11B [Source:MGI Symbol;Acc:MGI:1929913] Location: 12:107876662-107969861 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell CD4+ T cell excitatory neuron T cell epithelial cell Other: ATP-dependent chromatin remodelers
Adaptive Immune System Pathway Hierarchies & Genes CD28 dependent PI3K/Akt signaling (3 genes) Immune System Adaptive Immune System TCR signaling Downstream TCR signaling 2 genes Regulation of T cell activation by CD28 family Co-stimulation by CD28 CD28 dependent PI3K/Akt signaling 1 genes Co-inhibition by PD-1 (3 genes) Immune System Adaptive Immune System Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell 2 genes TCR signaling Downstream TCR signaling Regulation of T cell activation by CD28 family Co-inhibition by PD-1 1 genes Downstream TCR signaling (2 genes) Immune System Adaptive Immune System Signaling by the B Cell Receptor (BCR) Downstream signaling events of B Cell Receptor (BCR) Activation of NF-kappaB in B cells 1 genes TCR signaling Downstream TCR signaling 1 genes Rap1 signalling (1 genes) Immune System Adaptive Immune System Signaling by the B Cell Receptor (BCR) Downstream signaling events of B Cell Receptor (BCR) Activation of RAS in B cells Rap1 signalling 1 genes CD28 dependent PI3K/Akt signaling (2 genes) Immune System Adaptive Immune System Regulation of T cell activation by CD28 family Co-stimulation by CD28 CD28 dependent PI3K/Akt signaling 2 genes Calcineurin activates NFAT (1 genes) Immune System Adaptive Immune System Signaling by the B Cell Receptor (BCR) Downstream signaling events of B Cell Receptor (BCR) Calcineurin activates NFAT 1 genes Cross-presentation of particulate exogenous antigens (phagosomes) (1 genes) Immune System Adaptive Immune System Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation Cross-presentation of particulate exogenous antigens (phagosomes) 1 genes ER-Phagosome pathway (1 genes) Immune System Adaptive Immune System Class I MHC mediated antigen processing & presentation Antigen processing-Cross presentation ER-Phagosome pathway 1 genes Antigen processing: Ubiquitination & Proteasome degradation (6 genes) Immune System Adaptive Immune System Class I MHC mediated antigen processing & presentation Antigen processing: Ubiquitination & Proteasome degradation 6 genes Co-inhibition by CTLA4 (1 genes) Immune System Adaptive Immune System Regulation of T cell activation by CD28 family Co-inhibition by CTLA4 1 genes Generation of second messenger molecules (1 genes) Immune System Adaptive Immune System TCR signaling Generation of second messenger molecules 1 genes Phosphorylation of CD3 and TCR zeta chains (1 genes) Immune System Adaptive Immune System TCR signaling Phosphorylation of CD3 and TCR zeta chains 1 genes MHC class II antigen presentation (7 genes) Immune System Adaptive Immune System MHC class II antigen presentation 7 genes Rap1 signalling (3 genes) Immune System Adaptive Immune System Rap1 signalling 3 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH C3 Gene Information Basic Information Ensembl ID: ENSMUSG00000024164 Description: complement component 3 [Source:MGI Symbol;Acc:MGI:88227] Location: 17:57510970-57535136 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell fibroblast stellate cell stem cell endothelial cell stromal cell epithelial cell hepatocyte Other: Adaptive Immune System Innate Immune System Signaling by GPCR Cd247 Gene Information Basic Information Ensembl ID: ENSMUSG00000005763 Description: CD247 antigen [Source:MGI Symbol;Acc:MGI:88334] Location: 1:165616250-165704846 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell CD4+ T cell T cell hematopoietic cell Other: Adaptive Immune System Innate Immune System Cd36 Gene Information Basic Information Ensembl ID: ENSMUSG00000002944 Description: CD36 molecule [Source:MGI Symbol;Acc:MGI:107899] Location: 5:17986688-18093799 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macrophage Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Cd74 Gene Information Basic Information Ensembl ID: ENSMUSG00000024610 Description: CD74 antigen (invariant polypeptide of major histocompatibility complex%2C class II antigen-associated) [Source:MGI Symbol;Acc:MGI:96534] Location: 18:60936920-60945724 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell Naive B cell phagocyte epithelial cell monocyte antigen presenting cell T cell macrophage leukocyte Regulatory T cell myeloid derived suppressor cell immune cell natural killer cell Other: Adaptive Immune System Cell surface interactions at the vascular wall Cenpe Gene Information Basic Information Ensembl ID: ENSMUSG00000045328 Description: centromere protein E [Source:MGI Symbol;Acc:MGI:1098230] Location: 3:134918298-134979372 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Cell Cycle, Mitotic Dnm1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026825 Description: dynamin 1 [Source:MGI Symbol;Acc:MGI:107384] Location: 2:32198483-32243350 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Innate Immune System Membrane Trafficking Dync1li2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035770 Description: dynein%2C cytoplasmic 1 light intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107738] Location: 8:105144312-105169679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Membrane Trafficking Fbxl16 Gene Information Basic Information Ensembl ID: ENSMUSG00000025738 Description: F-box and leucine-rich repeat protein 16 [Source:MGI Symbol;Acc:MGI:2448488] Location: 17:26028059-26040229 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Post-translational protein modification Fyb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000022148 Description: FYN binding protein 1 [Source:MGI Symbol;Acc:MGI:1346327] Location: 15:6552334-6692794 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell Regulatory T cell phagocyte monocyte tuft cell dendritic cell myeloid progenitor cell Other: Adaptive Immune System Signal regulatory protein family interactions Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Icam5 Gene Information Basic Information Ensembl ID: ENSMUSG00000032174 Description: intercellular adhesion molecule 5%2C telencephalin [Source:MGI Symbol;Acc:MGI:109430] Location: 9:20943369-20950332 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Integrin cell surface interactions Itch Gene Information Basic Information Ensembl ID: ENSMUSG00000027598 Description: itchy%2C E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1202301] Location: 2:154975429-155068775 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Signaling by NOTCH Innate Immune System Kif11 Gene Information Basic Information Ensembl ID: ENSMUSG00000012443 Description: kinesin family member 11 [Source:MGI Symbol;Acc:MGI:1098231] Location: 19:37364851-37410307 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: hematopoietic cell Other: Adaptive Immune System Membrane Trafficking Factors involved in megakaryocyte development and platelet production Kif5a Gene Information Basic Information Ensembl ID: ENSMUSG00000074657 Description: kinesin family member 5A [Source:MGI Symbol;Acc:MGI:109564] Location: 10:127061565-127099217 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Lgmn Gene Information Basic Information Ensembl ID: ENSMUSG00000021190 Description: legumain [Source:MGI Symbol;Acc:MGI:1330838] Location: 12:102360343-102406072 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell phagocyte monocyte erythroid progenitor cell antigen presenting cell T cell macrophage leukocyte epithelial cell Other: Adaptive Immune System Innate Immune System Lmo7 Gene Information Basic Information Ensembl ID: ENSMUSG00000033060 Description: LIM domain only 7 [Source:MGI Symbol;Acc:MGI:1353586] Location: 14:101967386-102172146 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell cardiomyocyte pneumocyte Other: Adaptive Immune System Post-translational protein modification Nedd4l Gene Information Basic Information Ensembl ID: ENSMUSG00000024589 Description: neural precursor cell expressed%2C developmentally down-regulated gene 4-like [Source:MGI Symbol;Acc:MGI:1933754] Location: 18:65020776-65350899 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Adaptive Immune System RNA Polymerase II Transcription Signaling by TGFB family members Nfatc2 Gene Information Basic Information Ensembl ID: ENSMUSG00000027544 Description: nuclear factor of activated T cells%2C cytoplasmic%2C calcineurin dependent 2 [Source:MGI Symbol;Acc:MGI:102463] Location: 2:168318330-168443577 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: astrocyte Other: Adaptive Immune System Innate Immune System Nfkb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028163 Description: nuclear factor of kappa light polypeptide gene enhancer in B cells 1%2C p105 [Source:MGI Symbol;Acc:MGI:97312] Location: 3:135290416-135397308 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Prkcb Gene Information Basic Information Ensembl ID: ENSMUSG00000052889 Description: protein kinase C%2C beta [Source:MGI Symbol;Acc:MGI:97596] Location: 7:121887974-122233625 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron dendritic cell developing T cell Naive B cell monocyte mast cell Other: Transmission across Chemical Synapses Adaptive Immune System Signaling by WNT Prkcq Gene Information Basic Information Ensembl ID: ENSMUSG00000026778 Description: protein kinase C%2C theta [Source:MGI Symbol;Acc:MGI:97601] Location: 2:11176919-11306033 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell CD8+ T cell Specialized T cell Other: Apoptosis Adaptive Immune System Innate Immune System Prkn Gene Information Basic Information Ensembl ID: ENSMUSG00000023826 Description: parkin RBR E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1355296] Location: 17:11059271-12282248 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Regulated Necrosis Psmb8 Gene Information Basic Information Ensembl ID: ENSMUSG00000024338 Description: proteasome (prosome%2C macropain) subunit%2C beta type 8 (large multifunctional peptidase 7) [Source:MGI Symbol;Acc:MGI:1346527] Location: 17:34416695-34420428 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell dendritic cell developing T cell Regulatory T cell Naive B cell monocyte endothelial cell CD8+ T cell macrophage lymphocyte T cell Other: Adaptive Immune System Post-translational protein modification Pten Gene Information Basic Information Ensembl ID: ENSMUSG00000013663 Description: phosphatase and tensin homolog [Source:MGI Symbol;Acc:MGI:109583] Location: 19:32734897-32803560 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Inositol phosphate metabolism Metabolism of lipids Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Ptprc Gene Information Basic Information Ensembl ID: ENSMUSG00000026395 Description: protein tyrosine phosphatase receptor type C [Source:MGI Symbol;Acc:MGI:97810] Location: 1:137990599-138103446 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell phagocyte monocyte CD8+ T cell T cell Specialized T cell leukocyte lymphocyte hematopoietic cell myeloid cell immune cell Naive B cell epithelial cell Follicular B cell hematopoietic stem cell memory B cell Other: Innate Immune System Adaptive Immune System Nervous system development Rap1a Gene Information Basic Information Ensembl ID: ENSMUSG00000068798 Description: RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852] Location: 3:105634583-105708652 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell monocyte muscle cell dendritic cell plasma cell megakaryocyte Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Rap1gap Gene Information Basic Information Ensembl ID: ENSMUSG00000041351 Description: Rap1 GTPase-activating protein [Source:MGI Symbol;Acc:MGI:109338] Location: 4:137392037-137457172 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pancreatic cell oligodendrocyte precursor cell Other: Adaptive Immune System Nervous system development Rapgef4 Gene Information Basic Information Ensembl ID: ENSMUSG00000049044 Description: Rap guanine nucleotide exchange factor (GEF) 4 [Source:MGI Symbol;Acc:MGI:1917723] Location: 2:71811584-72087818 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell neuron adrenal cortical cell Other: Adaptive Immune System Integration of energy metabolism Integrin signaling Rasgrp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027347 Description: RAS guanyl releasing protein 1 [Source:MGI Symbol;Acc:MGI:1314635] Location: 2:117110474-117173482 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell Specialized T cell CD4+ T cell neuron Other: Adaptive Immune System Integrin signaling MAPK family signaling cascades Ube3a Gene Information Basic Information Ensembl ID: ENSMUSG00000025326 Description: ubiquitin protein ligase E3A [Source:MGI Symbol;Acc:MGI:105098] Location: 7:58878498-58961284 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron preadipocyte Other: Adaptive Immune System
Aerobic respiration and respiratory electron transport Pathway Hierarchies & Genes Complex I biogenesis (1 genes) Metabolism Aerobic respiration and respiratory electron transport Respiratory electron transport Complex I biogenesis 1 genes Malate-aspartate shuttle (2 genes) Metabolism Aerobic respiration and respiratory electron transport Respiratory electron transport Malate-aspartate shuttle 2 genes	Ndufa10 Gene Information Basic Information Ensembl ID: ENSMUSG00000026260 Description: NADH:ubiquinone oxidoreductase subunit A10 [Source:MGI Symbol;Acc:MGI:1914523] Location: 1:92366732-92401582 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Aerobic respiration and respiratory electron transport Slc25a12 Gene Information Basic Information Ensembl ID: ENSMUSG00000027010 Description: solute carrier family 25 (mitochondrial carrier%2C Aralar)%2C member 12 [Source:MGI Symbol;Acc:MGI:1926080] Location: 2:71101407-71198093 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Aerobic respiration and respiratory electron transport Metabolism of amino acids and derivatives Slc25a18 Gene Information Basic Information Ensembl ID: ENSMUSG00000004902 Description: solute carrier family 25 (mitochondrial carrier)%2C member 18 [Source:MGI Symbol;Acc:MGI:1919053] Location: 6:120750539-120771297 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Aerobic respiration and respiratory electron transport SLC-mediated transmembrane transport
Apoptosis Pathway Hierarchies & Genes Regulation of the apoptosome activity (2 genes) Programmed Cell Death Apoptosis Intrinsic Pathway for Apoptosis Apoptotic factor-mediated response Cytochrome c-mediated apoptotic response Formation of apoptosome Regulation of the apoptosome activity 2 genes Activation of BAD and translocation to mitochondria (1 genes) Programmed Cell Death Apoptosis Intrinsic Pathway for Apoptosis Activation of BH3-only proteins Activation of BAD and translocation to mitochondria 1 genes Activation of BIM and translocation to mitochondria (1 genes) Programmed Cell Death Apoptosis Intrinsic Pathway for Apoptosis Activation of BH3-only proteins Activation of BIM and translocation to mitochondria 1 genes Apoptotic cleavage of cell adhesion proteins (2 genes) Programmed Cell Death Apoptosis Apoptotic execution phase Apoptotic cleavage of cellular proteins Apoptotic cleavage of cell adhesion proteins 2 genes Apoptotic cleavage of cellular proteins (2 genes) Programmed Cell Death Apoptosis Apoptotic execution phase Apoptotic cleavage of cellular proteins 2 genes BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members (1 genes) Programmed Cell Death Apoptosis Intrinsic Pathway for Apoptosis BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members 1 genes Caspase activation via Death Receptors in the presence of ligand (1 genes) Programmed Cell Death Apoptosis Caspase activation via extrinsic apoptotic signalling pathway Caspase activation via Death Receptors in the presence of ligand 1 genes Apoptotic execution phase (1 genes) Programmed Cell Death Apoptosis Apoptotic execution phase 1 genes Regulation of Apoptosis (1 genes) Programmed Cell Death Apoptosis Regulation of Apoptosis 1 genes	Bcl2 Gene Information Basic Information Ensembl ID: ENSMUSG00000057329 Description: B cell leukemia/lymphoma 2 [Source:MGI Symbol;Acc:MGI:88138] Location: 1:106465908-106642004 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Innate Immune System Bcl2l1 Gene Information Basic Information Ensembl ID: ENSMUSG00000007659 Description: BCL2-like 1 [Source:MGI Symbol;Acc:MGI:88139] Location: 2:152622588-152673648 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Innate Immune System MAPK family signaling cascades Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Dnm1l Gene Information Basic Information Ensembl ID: ENSMUSG00000022789 Description: dynamin 1-like [Source:MGI Symbol;Acc:MGI:1921256] Location: 16:16130094-16176823 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Dsg2 Gene Information Basic Information Ensembl ID: ENSMUSG00000044393 Description: desmoglein 2 [Source:MGI Symbol;Acc:MGI:1196466] Location: 18:20691131-20737578 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell tuft cell epithelial cell Other: Apoptosis Keratinization Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk8 Gene Information Basic Information Ensembl ID: ENSMUSG00000021936 Description: mitogen-activated protein kinase 8 [Source:MGI Symbol;Acc:MGI:1346861] Location: 14:33099855-33169115 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Cytokine Signaling in Immune system Innate Immune System Opa1 Gene Information Basic Information Ensembl ID: ENSMUSG00000038084 Description: OPA1%2C mitochondrial dynamin like GTPase [Source:MGI Symbol;Acc:MGI:1921393] Location: 16:29398152-29473702 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system Prkcq Gene Information Basic Information Ensembl ID: ENSMUSG00000026778 Description: protein kinase C%2C theta [Source:MGI Symbol;Acc:MGI:97601] Location: 2:11176919-11306033 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell CD8+ T cell Specialized T cell Other: Apoptosis Adaptive Immune System Innate Immune System Tlr4 Gene Information Basic Information Ensembl ID: ENSMUSG00000039005 Description: toll-like receptor 4 [Source:MGI Symbol;Acc:MGI:96824] Location: 4:66745821-66848521 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte Other: Apoptosis Innate Immune System Cellular responses to stress
Aquaporin-mediated transport Pathway Hierarchies & Genes Passive transport by Aquaporins (5 genes) Transport of small molecules Aquaporin-mediated transport Vasopressin regulates renal water homeostasis via Aquaporins 3 genes Passive transport by Aquaporins 2 genes	Aqp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000004655 Description: aquaporin 1 [Source:MGI Symbol;Acc:MGI:103201] Location: 6:55313417-55325540 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell hematopoietic progenitor cell erythroblast podocyte Other: O2/CO2 exchange in erythrocytes Aquaporin-mediated transport Aqp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000024411 Description: aquaporin 4 [Source:MGI Symbol;Acc:MGI:107387] Location: 18:15522553-15544039 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stem cell glial cell astrocyte Other: Aquaporin-mediated transport Avpr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031390 Description: arginine vasopressin receptor 2 [Source:MGI Symbol;Acc:MGI:88123] Location: X:72935708-72939108 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Membrane Trafficking Signaling by GPCR Aquaporin-mediated transport Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Myo5b Gene Information Basic Information Ensembl ID: ENSMUSG00000025885 Description: myosin VB [Source:MGI Symbol;Acc:MGI:106598] Location: 18:74574007-74904564 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Aquaporin-mediated transport
Aspirin ADME Pathway Hierarchies & Genes Aspirin ADME (1 genes) Drug ADME Aspirin ADME 1 genes	Bche Gene Information Basic Information Ensembl ID: ENSMUSG00000027792 Description: butyrylcholinesterase [Source:MGI Symbol;Acc:MGI:894278] Location: 3:73543141-73615748 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Peptide hormone metabolism Aspirin ADME
Base Excision Repair Pathway Hierarchies & Genes Displacement of DNA glycosylase by APEX1 (1 genes) DNA Repair Base Excision Repair Base-Excision Repair, AP Site Formation Depyrimidination Cleavage of the damaged pyrimidine Resolution of Abasic Sites (AP sites) Displacement of DNA glycosylase by APEX1 1 genes	Ung Gene Information Basic Information Ensembl ID: ENSMUSG00000029591 Description: uracil DNA glycosylase [Source:MGI Symbol;Acc:MGI:109352] Location: 5:114268447-114277384 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Base Excision Repair
Binding and Uptake of Ligands by Scavenger Receptors Pathway Hierarchies & Genes Scavenging by Class A Receptors (1 genes) Vesicle-mediated transport Binding and Uptake of Ligands by Scavenger Receptors Scavenging by Class A Receptors 1 genes Scavenging by Class B Receptors (1 genes) Vesicle-mediated transport Binding and Uptake of Ligands by Scavenger Receptors Scavenging by Class B Receptors 1 genes	Cd36 Gene Information Basic Information Ensembl ID: ENSMUSG00000002944 Description: CD36 molecule [Source:MGI Symbol;Acc:MGI:107899] Location: 5:17986688-18093799 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macrophage Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Msr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025044 Description: macrophage scavenger receptor 1 [Source:MGI Symbol;Acc:MGI:98257] Location: 8:40034726-40095714 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte antigen presenting cell Other: Binding and Uptake of Ligands by Scavenger Receptors
Biological oxidations Pathway Hierarchies & Genes Endogenous sterols (1 genes) Metabolism Biological oxidations Phase I - Functionalization of compounds Cytochrome P450 - arranged by substrate type Endogenous sterols 1 genes Vitamins (1 genes) Metabolism Biological oxidations Phase I - Functionalization of compounds Cytochrome P450 - arranged by substrate type Vitamins 1 genes	Cyp26b1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063415 Description: cytochrome P450%2C family 26%2C subfamily b%2C polypeptide 1 [Source:MGI Symbol;Acc:MGI:2176159] Location: 6:84548396-84570890 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell ectodermal cell astrocyte Other: Signaling by Nuclear Receptors Biological oxidations Pomc Gene Information Basic Information Ensembl ID: ENSMUSG00000020660 Description: pro-opiomelanocortin-alpha [Source:MGI Symbol;Acc:MGI:97742] Location: 12:4004951-4010642 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Biological oxidations Peptide hormone metabolism Signaling by GPCR
Cardiac conduction Pathway Hierarchies & Genes Phase 2 - plateau phase (1 genes) Muscle contraction Cardiac conduction Phase 0 - rapid depolarisation Phase 2 - plateau phase 1 genes Ion homeostasis (10 genes) Muscle contraction Cardiac conduction Ion homeostasis 10 genes Phase 1 - inactivation of fast Na+ channels (1 genes) Muscle contraction Cardiac conduction Phase 1 - inactivation of fast Na+ channels 1 genes Phase 4 - resting membrane potential (3 genes) Muscle contraction Cardiac conduction Phase 4 - resting membrane potential 3 genes Physiological factors (1 genes) Muscle contraction Cardiac conduction Physiological factors 1 genes	Abcc9 Gene Information Basic Information Ensembl ID: ENSMUSG00000030249 Description: ATP-binding cassette%2C sub-family C member 9 [Source:MGI Symbol;Acc:MGI:1352630] Location: 6:142533588-142648041 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell pericyte Other: Potassium Channels ABC-family proteins mediated transport Cardiac conduction Atp2b4 Gene Information Basic Information Ensembl ID: ENSMUSG00000026463 Description: ATPase%2C Ca++ transporting%2C plasma membrane 4 [Source:MGI Symbol;Acc:MGI:88111] Location: 1:133627195-133728779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell hematopoietic progenitor cell Other: Platelet homeostasis Cardiac conduction Ion channel transport Cacna1c Gene Information Basic Information Ensembl ID: ENSMUSG00000051331 Description: calcium channel%2C voltage-dependent%2C L type%2C alpha 1C subunit [Source:MGI Symbol;Acc:MGI:103013] Location: 6:118564201-119173851 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte fibroblast adrenal cortical cell theca cell Other: Integration of energy metabolism Cardiac conduction Camk2a Gene Information Basic Information Ensembl ID: ENSMUSG00000024617 Description: calcium/calmodulin-dependent protein kinase II alpha [Source:MGI Symbol;Acc:MGI:88256] Location: 18:61058690-61121224 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Signaling by WNT Camk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000057897 Description: calcium/calmodulin-dependent protein kinase II%2C beta [Source:MGI Symbol;Acc:MGI:88257] Location: 11:5919644-6016362 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: kidney cell neuron enteroendocrine cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2d Gene Information Basic Information Ensembl ID: ENSMUSG00000053819 Description: calcium/calmodulin-dependent protein kinase II%2C delta [Source:MGI Symbol;Acc:MGI:1341265] Location: 3:126389951-126639975 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2g Gene Information Basic Information Ensembl ID: ENSMUSG00000021820 Description: calcium/calmodulin-dependent protein kinase II gamma [Source:MGI Symbol;Acc:MGI:88259] Location: 14:20784943-20844156 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Corin Gene Information Basic Information Ensembl ID: ENSMUSG00000005220 Description: corin%2C serine peptidase [Source:MGI Symbol;Acc:MGI:1349451] Location: 5:72457368-72661816 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Cardiac conduction Fxyd6 Gene Information Basic Information Ensembl ID: ENSMUSG00000066705 Description: FXYD domain-containing ion transport regulator 6 [Source:MGI Symbol;Acc:MGI:1890226] Location: 9:45281483-45307457 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell interneuron glial cell enteroendocrine cell dendritic cell Other: Cardiac conduction Ion channel transport Kcnip2 Gene Information Basic Information Ensembl ID: ENSMUSG00000025221 Description: Kv channel-interacting protein 2 [Source:MGI Symbol;Acc:MGI:2135916] Location: 19:45780278-45804500 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Cardiac conduction Kcnj2 Gene Information Basic Information Ensembl ID: ENSMUSG00000041695 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 2 [Source:MGI Symbol;Acc:MGI:104744] Location: 11:110956990-110967647 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Potassium Channels Cardiac conduction Kcnj4 Gene Information Basic Information Ensembl ID: ENSMUSG00000044216 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 4 [Source:MGI Symbol;Acc:MGI:104743] Location: 15:79367915-79389442 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Potassium Channels Cardiac conduction Kcnk9 Gene Information Basic Information Ensembl ID: ENSMUSG00000036760 Description: potassium channel%2C subfamily K%2C member 9 [Source:MGI Symbol;Acc:MGI:3521816] Location: 15:72372938-72418189 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Cardiac conduction Nos1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029361 Description: nitric oxide synthase 1%2C neuronal [Source:MGI Symbol;Acc:MGI:97360] Location: 5:117919097-118096905 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macula densa cell Other: Innate Immune System Platelet homeostasis Cardiac conduction Ryr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000021313 Description: ryanodine receptor 2%2C cardiac [Source:MGI Symbol;Acc:MGI:99685] Location: 13:11567988-12121831 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron endocrine cell cardiomyocyte smooth muscle cell theca cell Other: Ion channel transport Cardiac conduction Ryr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000057378 Description: ryanodine receptor 3 [Source:MGI Symbol;Acc:MGI:99684] Location: 2:112461700-113047441 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron skeletal muscle cell Other: Cardiac conduction Ion channel transport
Cell Cycle Checkpoints Pathway Hierarchies & Genes Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (3 genes) Cell Cycle Cell Cycle Checkpoints Mitotic Spindle Checkpoint Amplification of signal from the kinetochores Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal 3 genes p53-Dependent G1 DNA Damage Response (1 genes) Cell Cycle Cell Cycle Checkpoints G1/S DNA Damage Checkpoints p53-Dependent G1/S DNA damage checkpoint p53-Dependent G1 DNA Damage Response 1 genes Activation of ATR in response to replication stress (1 genes) Cell Cycle Cell Cycle Checkpoints G2/M Checkpoints Activation of ATR in response to replication stress 1 genes	Cdkn1a Gene Information Basic Information Ensembl ID: ENSMUSG00000023067 Description: cyclin dependent kinase inhibitor 1A [Source:MGI Symbol;Acc:MGI:104556] Location: 17:29309950-29319701 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast muscle cell smooth muscle cell schwann cell monocyte epithelial cell Other: Cellular responses to stress Cell Cycle, Mitotic Cell Cycle Checkpoints Cenpe Gene Information Basic Information Ensembl ID: ENSMUSG00000045328 Description: centromere protein E [Source:MGI Symbol;Acc:MGI:1098230] Location: 3:134918298-134979372 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Cell Cycle, Mitotic Dync1li2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035770 Description: dynein%2C cytoplasmic 1 light intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107738] Location: 8:105144312-105169679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Membrane Trafficking Mcm6 Gene Information Basic Information Ensembl ID: ENSMUSG00000026355 Description: minichromosome maintenance complex component 6 [Source:MGI Symbol;Acc:MGI:1298227] Location: 1:128259327-128287401 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: erythroblast Other: DNA Replication Pre-Initiation Synthesis of DNA Cell Cycle, Mitotic Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress
Cell Cycle, Mitotic Pathway Hierarchies & Genes Cyclin D associated events in G1 (1 genes) Cell Cycle Cell Cycle, Mitotic M Phase Mitotic Metaphase and Anaphase Mitotic Anaphase Nuclear Envelope (NE) Reassembly Initiation of Nuclear Envelope (NE) Reformation Mitotic G2-G2/M phases G2/M Transition Cyclin A/B1/B2 associated events during G2/M transition Mitotic G1 phase and G1/S transition G1 Phase Cyclin D associated events in G1 1 genes Cyclin E associated events during G1/S transition (2 genes) Cell Cycle Cell Cycle, Mitotic S Phase Cyclin A:Cdk2-associated events at S phase entry SCF(Skp2)-mediated degradation of p27/p21 Mitotic G2-G2/M phases G2/M Transition The role of GTSE1 in G2/M progression after G2 checkpoint Mitotic G1 phase and G1/S transition 1 genes G1/S Transition Cyclin E associated events during G1/S transition 1 genes Cyclin A:Cdk2-associated events at S phase entry (1 genes) Cell Cycle Cell Cycle, Mitotic Mitotic G1 phase and G1/S transition G1/S Transition Cyclin E associated events during G1/S transition S Phase Cyclin A:Cdk2-associated events at S phase entry 1 genes Depolymerization of the Nuclear Lamina (1 genes) Cell Cycle Cell Cycle, Mitotic M Phase Mitotic Prophase Nuclear Envelope Breakdown Depolymerization of the Nuclear Lamina 1 genes Drug-mediated inhibition of CDK4/CDK6 activity (1 genes) Cell Cycle Cell Cycle, Mitotic Mitotic G1 phase and G1/S transition G1 Phase Cyclin D associated events in G1 Drug-mediated inhibition of CDK4/CDK6 activity 1 genes Separation of Sister Chromatids (3 genes) Cell Cycle Cell Cycle, Mitotic M Phase Mitotic Metaphase and Anaphase Mitotic Anaphase Separation of Sister Chromatids 3 genes Golgi Cisternae Pericentriolar Stack Reorganization (2 genes) Cell Cycle Cell Cycle, Mitotic M Phase Mitotic Prophase Golgi Cisternae Pericentriolar Stack Reorganization 2 genes Regulation of PLK1 Activity at G2/M Transition (1 genes) Cell Cycle Cell Cycle, Mitotic Mitotic G2-G2/M phases G2/M Transition Regulation of PLK1 Activity at G2/M Transition 1 genes S Phase (1 genes) Cell Cycle Cell Cycle, Mitotic Mitotic G1 phase and G1/S transition G1/S Transition S Phase 1 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Ccnd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000070348 Description: cyclin D1 [Source:MGI Symbol;Acc:MGI:88313] Location: 7:144483668-144493662 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte endothelial cell glial cell dendritic cell epithelial cell Other: Chromatin modifying enzymes Cell Cycle, Mitotic RNA Polymerase II Transcription Ccnd2 Gene Information Basic Information Ensembl ID: ENSMUSG00000000184 Description: cyclin D2 [Source:MGI Symbol;Acc:MGI:88314] Location: 6:127102125-127129156 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell hematopoietic stem cell endothelial cell stem cell smooth muscle cell fibroblast CD4+ T cell pancreatic cell goblet cell mural cell Other: Cell Cycle, Mitotic RNA Polymerase II Transcription Cdkn1a Gene Information Basic Information Ensembl ID: ENSMUSG00000023067 Description: cyclin dependent kinase inhibitor 1A [Source:MGI Symbol;Acc:MGI:104556] Location: 17:29309950-29319701 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast muscle cell smooth muscle cell schwann cell monocyte epithelial cell Other: Cellular responses to stress Cell Cycle, Mitotic Cell Cycle Checkpoints Cenpe Gene Information Basic Information Ensembl ID: ENSMUSG00000045328 Description: centromere protein E [Source:MGI Symbol;Acc:MGI:1098230] Location: 3:134918298-134979372 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Cell Cycle, Mitotic Dync1li2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035770 Description: dynein%2C cytoplasmic 1 light intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107738] Location: 8:105144312-105169679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Membrane Trafficking Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mcm6 Gene Information Basic Information Ensembl ID: ENSMUSG00000026355 Description: minichromosome maintenance complex component 6 [Source:MGI Symbol;Acc:MGI:1298227] Location: 1:128259327-128287401 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: erythroblast Other: DNA Replication Pre-Initiation Synthesis of DNA Cell Cycle, Mitotic Optn Gene Information Basic Information Ensembl ID: ENSMUSG00000026672 Description: optineurin [Source:MGI Symbol;Acc:MGI:1918898] Location: 2:5025453-5068862 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Macroautophagy Innate Immune System Membrane Trafficking Ppp2r2a Gene Information Basic Information Ensembl ID: ENSMUSG00000022052 Description: protein phosphatase 2%2C regulatory subunit B%2C alpha [Source:MGI Symbol;Acc:MGI:1919228] Location: 14:67251505-67309893 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: adrenal cortical cell Other: Cell Cycle, Mitotic Nonsense-Mediated Decay (NMD) Cellular responses to mechanical stimuli Prkcb Gene Information Basic Information Ensembl ID: ENSMUSG00000052889 Description: protein kinase C%2C beta [Source:MGI Symbol;Acc:MGI:97596] Location: 7:121887974-122233625 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron dendritic cell developing T cell Naive B cell monocyte mast cell Other: Transmission across Chemical Synapses Adaptive Immune System Signaling by WNT Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress
Cell junction organization Pathway Hierarchies & Genes Degradation of CDH1 (2 genes) Cell-Cell communication Cell junction organization Cell-cell junction organization Adherens junctions interactions Regulation of Homotypic Cell-Cell Adhesion Regulation of Expression and Function of Type I Classical Cadherins Regulation of CDH1 Expression and Function Regulation of CDH1 Function Degradation of CDH1 2 genes Regulation of CDH1 Function (1 genes) Cell-Cell communication Cell junction organization Cell-cell junction organization Adherens junctions interactions Regulation of Homotypic Cell-Cell Adhesion Regulation of Expression and Function of Type I Classical Cadherins Regulation of CDH1 Expression and Function Regulation of CDH1 Function 1 genes Regulation of CDH1 posttranslational processing and trafficking to plasma membrane (1 genes) Cell-Cell communication Cell junction organization Cell-cell junction organization Adherens junctions interactions Regulation of Homotypic Cell-Cell Adhesion Regulation of Expression and Function of Type I Classical Cadherins Regulation of CDH1 Expression and Function Regulation of CDH1 posttranslational processing and trafficking to plasma membrane 1 genes Regulation of CDH11 gene transcription (1 genes) Cell-Cell communication Cell junction organization Cell-cell junction organization Adherens junctions interactions Regulation of Homotypic Cell-Cell Adhesion Regulation of Expression and Function of Type II Classical Cadherins Regulation of CDH11 Expression and Function Regulation of CDH11 gene transcription 1 genes Adherens junctions interactions (2 genes) Cell-Cell communication Cell junction organization Cell-cell junction organization Adherens junctions interactions 2 genes Tight junction interactions (1 genes) Cell-Cell communication Cell junction organization Cell-cell junction organization Tight junction interactions 1 genes	Acta2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035783 Description: actin alpha 2%2C smooth muscle%2C aorta [Source:MGI Symbol;Acc:MGI:87909] Location: 19:34218490-34232990 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stellate cell endothelial cell stem cell smooth muscle cell fibroblast mural cell mesangial cell progenitor cell muscle cell mesenchymal cell Other: Non-integrin membrane-ECM interactions Smooth Muscle Contraction Cell junction organization Cdh6 Gene Information Basic Information Ensembl ID: ENSMUSG00000039385 Description: cadherin 6 [Source:MGI Symbol;Acc:MGI:107435] Location: 15:13028787-13173761 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell glial cell neuron Other: Cell junction organization Cdh9 Gene Information Basic Information Ensembl ID: ENSMUSG00000025370 Description: cadherin 9 [Source:MGI Symbol;Acc:MGI:107433] Location: 15:16728842-16857180 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Cell junction organization Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Pard3 Gene Information Basic Information Ensembl ID: ENSMUSG00000025812 Description: par-3 family cell polarity regulator [Source:MGI Symbol;Acc:MGI:2135608] Location: 8:127790643-128338767 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell motor neuron Other: Cell junction organization Signaling by TGFB family members Pcsk6 Gene Information Basic Information Ensembl ID: ENSMUSG00000030513 Description: proprotein convertase subtilisin/kexin type 6 [Source:MGI Symbol;Acc:MGI:102897] Location: 7:65511482-65700134 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell epithelial cell fibroblast neuron retina cell mesenchymal cell Other: Plasma lipoprotein assembly, remodeling, and clearance Cell junction organization Signaling by Receptor Tyrosine Kinases Zeb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000026872 Description: zinc finger E-box binding homeobox 2 [Source:MGI Symbol;Acc:MGI:1344407] Location: 2:44873644-45007407 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell stromal cell phagocyte monocyte fibroblast glial cell motor neuron antigen presenting cell Other: Cell junction organization
Cell surface interactions at the vascular wall Pathway Hierarchies & Genes Tie2 Signaling (13 genes) Hemostasis Cell surface interactions at the vascular wall 7 genes PECAM1 interactions 5 genes Tie2 Signaling 1 genes	Angpt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000022309 Description: angiopoietin 1 [Source:MGI Symbol;Acc:MGI:108448] Location: 15:42288119-42540373 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast preadipocyte cardiomyocyte astrocyte Other: Cell surface interactions at the vascular wall MAPK family signaling cascades Cd44 Gene Information Basic Information Ensembl ID: ENSMUSG00000005087 Description: CD44 antigen [Source:MGI Symbol;Acc:MGI:88338] Location: 2:102641486-102732010 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell phagocyte monocyte granulocyte neutrophil macrophage progenitor cell Other: Cell surface interactions at the vascular wall Integrin cell surface interactions Innate Immune System Cd74 Gene Information Basic Information Ensembl ID: ENSMUSG00000024610 Description: CD74 antigen (invariant polypeptide of major histocompatibility complex%2C class II antigen-associated) [Source:MGI Symbol;Acc:MGI:96534] Location: 18:60936920-60945724 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell Naive B cell phagocyte epithelial cell monocyte antigen presenting cell T cell macrophage leukocyte Regulatory T cell myeloid derived suppressor cell immune cell natural killer cell Other: Adaptive Immune System Cell surface interactions at the vascular wall Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Itgax Gene Information Basic Information Ensembl ID: ENSMUSG00000030789 Description: integrin alpha X [Source:MGI Symbol;Acc:MGI:96609] Location: 7:127728719-127749829 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell phagocyte macrophage dendritic cell Other: Innate Immune System Cell surface interactions at the vascular wall Integrin cell surface interactions Jam3 Gene Information Basic Information Ensembl ID: ENSMUSG00000031990 Description: junction adhesion molecule 3 [Source:MGI Symbol;Acc:MGI:1933825] Location: 9:27008680-27066717 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell glial cell muscle cell schwann cell dendritic cell Other: Cell surface interactions at the vascular wall Integrin cell surface interactions Mertk Gene Information Basic Information Ensembl ID: ENSMUSG00000014361 Description: MER proto-oncogene tyrosine kinase [Source:MGI Symbol;Acc:MGI:96965] Location: 2:128540876-128644814 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell epithelial cell macrophage Other: Cell surface interactions at the vascular wall Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Slc7a10 Gene Information Basic Information Ensembl ID: ENSMUSG00000030495 Description: solute carrier family 7 (cationic amino acid transporter%2C y+ system)%2C member 10 [Source:MGI Symbol;Acc:MGI:1858261] Location: 7:34885810-34900539 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell astrocyte adipocyte preadipocyte Other: Cell surface interactions at the vascular wall SLC-mediated transmembrane transport Slc7a11 Gene Information Basic Information Ensembl ID: ENSMUSG00000027737 Description: solute carrier family 7 (cationic amino acid transporter%2C y+ system)%2C member 11 [Source:MGI Symbol;Acc:MGI:1347355] Location: 3:49846975-50398063 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell fibroblast granulocyte monocyte retinal pigment epithelial cell Other: Cell surface interactions at the vascular wall SLC-mediated transmembrane transport Tgfb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000002603 Description: transforming growth factor%2C beta 1 [Source:MGI Symbol;Acc:MGI:98725] Location: 7:25386427-25404502 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell hematopoietic stem cell phagocyte monocyte leukocyte megakaryocyte Other: Cell surface interactions at the vascular wall Non-integrin membrane-ECM interactions Elastic fibre formation
Cellular responses to mechanical stimuli Pathway Hierarchies & Genes High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (2 genes) Cellular responses to stimuli Cellular responses to mechanical stimuli Response of endothelial cells to shear stress High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells 2 genes Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (3 genes) Cellular responses to stimuli Cellular responses to mechanical stimuli Response of endothelial cells to shear stress Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells 3 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Nfkb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028163 Description: nuclear factor of kappa light polypeptide gene enhancer in B cells 1%2C p105 [Source:MGI Symbol;Acc:MGI:97312] Location: 3:135290416-135397308 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Ppp2r2a Gene Information Basic Information Ensembl ID: ENSMUSG00000022052 Description: protein phosphatase 2%2C regulatory subunit B%2C alpha [Source:MGI Symbol;Acc:MGI:1919228] Location: 14:67251505-67309893 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: adrenal cortical cell Other: Cell Cycle, Mitotic Nonsense-Mediated Decay (NMD) Cellular responses to mechanical stimuli
Cellular responses to stress Pathway Hierarchies & Genes Regulation of HSF1-mediated heat shock response (5 genes) Cellular responses to stimuli Cellular responses to stress Cellular Senescence Oxidative Stress Induced Senescence 3 genes Cellular response to heat stress Regulation of HSF1-mediated heat shock response 2 genes Mitochondrial unfolded protein response (UPRmt) (1 genes) Cellular responses to stimuli Cellular responses to stress Cellular response to chemical stress KEAP1-NFE2L2 pathway Mitochondrial unfolded protein response (UPRmt) 1 genes Nuclear events mediated by NFE2L2 (1 genes) Cellular responses to stimuli Cellular responses to stress Cellular response to chemical stress KEAP1-NFE2L2 pathway Nuclear events mediated by NFE2L2 1 genes Amino acids regulate mTORC1 (1 genes) Cellular responses to stimuli Cellular responses to stress Cellular response to starvation Amino acids regulate mTORC1 1 genes Detoxification of Reactive Oxygen Species (1 genes) Cellular responses to stimuli Cellular responses to stress Cellular response to chemical stress Detoxification of Reactive Oxygen Species 1 genes HSF1-dependent transactivation (4 genes) Cellular responses to stimuli Cellular responses to stress Cellular response to heat stress HSF1-dependent transactivation 4 genes Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha (1 genes) Cellular responses to stimuli Cellular responses to stress Cellular response to hypoxia Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha 1 genes Regulation of HSF1-mediated heat shock response (1 genes) Cellular responses to stimuli Cellular responses to stress Cellular response to heat stress Regulation of HSF1-mediated heat shock response 1 genes Regulation of gene expression by Hypoxia-inducible Factor (1 genes) Cellular responses to stimuli Cellular responses to stress Cellular response to hypoxia Regulation of gene expression by Hypoxia-inducible Factor 1 genes Senescence-Associated Secretory Phenotype (SASP) (2 genes) Cellular responses to stimuli Cellular responses to stress Cellular Senescence Senescence-Associated Secretory Phenotype (SASP) 2 genes HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (1 genes) Cellular responses to stimuli Cellular responses to stress HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand 1 genes Heme signaling (1 genes) Cellular responses to stimuli Cellular responses to stress Heme signaling 1 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Atp6v1a Gene Information Basic Information Ensembl ID: ENSMUSG00000052459 Description: ATPase%2C H+ transporting%2C lysosomal V1 subunit A [Source:MGI Symbol;Acc:MGI:1201780] Location: 16:43905765-43960068 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Cellular responses to stress Signaling by Receptor Tyrosine Kinases Camk2a Gene Information Basic Information Ensembl ID: ENSMUSG00000024617 Description: calcium/calmodulin-dependent protein kinase II alpha [Source:MGI Symbol;Acc:MGI:88256] Location: 18:61058690-61121224 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Signaling by WNT Camk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000057897 Description: calcium/calmodulin-dependent protein kinase II%2C beta [Source:MGI Symbol;Acc:MGI:88257] Location: 11:5919644-6016362 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: kidney cell neuron enteroendocrine cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2d Gene Information Basic Information Ensembl ID: ENSMUSG00000053819 Description: calcium/calmodulin-dependent protein kinase II%2C delta [Source:MGI Symbol;Acc:MGI:1341265] Location: 3:126389951-126639975 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2g Gene Information Basic Information Ensembl ID: ENSMUSG00000021820 Description: calcium/calmodulin-dependent protein kinase II gamma [Source:MGI Symbol;Acc:MGI:88259] Location: 14:20784943-20844156 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Cdkn1a Gene Information Basic Information Ensembl ID: ENSMUSG00000023067 Description: cyclin dependent kinase inhibitor 1A [Source:MGI Symbol;Acc:MGI:104556] Location: 17:29309950-29319701 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast muscle cell smooth muscle cell schwann cell monocyte epithelial cell Other: Cellular responses to stress Cell Cycle, Mitotic Cell Cycle Checkpoints Dync1li2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035770 Description: dynein%2C cytoplasmic 1 light intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107738] Location: 8:105144312-105169679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Membrane Trafficking Egln3 Gene Information Basic Information Ensembl ID: ENSMUSG00000035105 Description: egl-9 family hypoxia-inducible factor 3 [Source:MGI Symbol;Acc:MGI:1932288] Location: 12:54225767-54250646 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cellular responses to stress Gpx3 Gene Information Basic Information Ensembl ID: ENSMUSG00000018339 Description: glutathione peroxidase 3 [Source:MGI Symbol;Acc:MGI:105102] Location: 11:54793279-54801203 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast endocrine cell stem cell stromal cell phagocyte epithelial cell cardiomyocyte muscle cell enteroendocrine cell Other: Cellular responses to stress Hif1a Gene Information Basic Information Ensembl ID: ENSMUSG00000021109 Description: hypoxia inducible factor 1%2C alpha subunit [Source:MGI Symbol;Acc:MGI:106918] Location: 12:73948149-73994304 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell Regulatory T cell epithelial cell retinal pigment epithelial cell dendritic cell Other: Cellular responses to stress Post-translational protein modification Signaling by Non-Receptor Tyrosine Kinases Map4k4 Gene Information Basic Information Ensembl ID: ENSMUSG00000026074 Description: mitogen-activated protein kinase kinase kinase kinase 4 [Source:MGI Symbol;Acc:MGI:1349394] Location: 1:39940073-40065470 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast glial cell stromal cell Other: Cellular responses to stress Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk8 Gene Information Basic Information Ensembl ID: ENSMUSG00000021936 Description: mitogen-activated protein kinase 8 [Source:MGI Symbol;Acc:MGI:1346861] Location: 14:33099855-33169115 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Cytokine Signaling in Immune system Innate Immune System Prkaa2 Gene Information Basic Information Ensembl ID: ENSMUSG00000028518 Description: protein kinase%2C AMP-activated%2C alpha 2 catalytic subunit [Source:MGI Symbol;Acc:MGI:1336173] Location: 4:104887071-104967087 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Macroautophagy Integration of energy metabolism MTOR signalling Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress Rps6ka1 Gene Information Basic Information Ensembl ID: ENSMUSG00000003644 Description: ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:104558] Location: 4:133574601-133615108 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Innate Immune System Tlr4 Gene Information Basic Information Ensembl ID: ENSMUSG00000039005 Description: toll-like receptor 4 [Source:MGI Symbol;Acc:MGI:96824] Location: 4:66745821-66848521 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte Other: Apoptosis Innate Immune System Cellular responses to stress
Chromatin modifying enzymes Pathway Hierarchies & Genes PKMTs methylate histone lysines (2 genes) Chromatin organization Chromatin modifying enzymes PKMTs methylate histone lysines 2 genes	Ccnd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000070348 Description: cyclin D1 [Source:MGI Symbol;Acc:MGI:88313] Location: 7:144483668-144493662 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte endothelial cell glial cell dendritic cell epithelial cell Other: Chromatin modifying enzymes Cell Cycle, Mitotic RNA Polymerase II Transcription Nfkb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028163 Description: nuclear factor of kappa light polypeptide gene enhancer in B cells 1%2C p105 [Source:MGI Symbol;Acc:MGI:97312] Location: 3:135290416-135397308 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System
Chromosome Maintenance Pathway Hierarchies & Genes Telomere Extension By Telomerase (1 genes) Cell Cycle Chromosome Maintenance Telomere Maintenance Extension of Telomeres Telomere Extension By Telomerase 1 genes	Pif1 Gene Information Basic Information Ensembl ID: ENSMUSG00000041064 Description: PIF1 5'-to-3' DNA helicase [Source:MGI Symbol;Acc:MGI:2143057] Location: 9:65494442-65503249 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Chromosome Maintenance
Cilium Assembly Pathway Hierarchies & Genes BBSome-mediated cargo-targeting to cilium (1 genes) Organelle biogenesis and maintenance Cilium Assembly Cargo trafficking to the periciliary membrane BBSome-mediated cargo-targeting to cilium 1 genes	Mchr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000050164 Description: melanin-concentrating hormone receptor 1 [Source:MGI Symbol;Acc:MGI:2180756] Location: 15:81119700-81123165 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Cilium Assembly
Collagen formation Pathway Hierarchies & Genes Anchoring fibril formation (2 genes) Extracellular matrix organization Collagen formation Collagen biosynthesis and modifying enzymes 1 genes Assembly of collagen fibrils and other multimeric structures Anchoring fibril formation 1 genes Assembly of collagen fibrils and other multimeric structures (5 genes) Extracellular matrix organization Collagen formation Collagen biosynthesis and modifying enzymes Collagen chain trimerization 1 genes Assembly of collagen fibrils and other multimeric structures 4 genes	Adamts2 Gene Information Basic Information Ensembl ID: ENSMUSG00000036545 Description: ADAM metallopeptidase with thrombospondin type 1 motif 2 [Source:MGI Symbol;Acc:MGI:1347356] Location: 11:50492911-50698400 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast epithelial cell osteoblast Other: Collagen formation Post-translational protein modification Col11a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027966 Description: collagen%2C type XI%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88446] Location: 3:113824189-114014367 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell Other: Degradation of the extracellular matrix Collagen formation Non-integrin membrane-ECM interactions Col18a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001435 Description: collagen%2C type XVIII%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88451] Location: 10:76888012-77002382 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stellate cell glial cell smooth muscle cell neuron epithelial cell Other: Degradation of the extracellular matrix Collagen formation Integrin cell surface interactions Col23a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063564 Description: collagen%2C type XXIII%2C alpha 1 [Source:MGI Symbol;Acc:MGI:2653243] Location: 11:51180747-51474745 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast glial cell club Other: Collagen formation Col5a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026837 Description: collagen%2C type V%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88457] Location: 2:27776437-27929526 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell epithelial cell Other: Integrin cell surface interactions Degradation of the extracellular matrix Collagen formation Col8a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000068196 Description: collagen%2C type VIII%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88463] Location: 16:57444621-57575100 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell fibroblast glial cell epithelial cell Other: Degradation of the extracellular matrix Collagen formation Integrin cell surface interactions Tll1 Gene Information Basic Information Ensembl ID: ENSMUSG00000053626 Description: tolloid-like [Source:MGI Symbol;Acc:MGI:106923] Location: 8:64467965-64659305 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell interneuron Other: Collagen formation
Cytokine Signaling in Immune system Pathway Hierarchies & Genes Signaling by CSF3 (G-CSF) (2 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-6 family signaling Interleukin-6 signaling Interferon Signaling Interferon alpha/beta signaling Regulation of IFNA/IFNB signaling 1 genes Signaling by CSF3 (G-CSF) 1 genes Growth hormone receptor signaling (3 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-17 signaling 2 genes Interferon Signaling Interferon gamma signaling IFNG signaling activates MAPKs Growth hormone receptor signaling 1 genes Growth hormone receptor signaling (1 genes) Immune System Cytokine Signaling in Immune system Interferon Signaling Antiviral mechanism by IFN-stimulated genes ISG15 antiviral mechanism Signaling by Interleukins Interleukin-17 signaling Growth hormone receptor signaling 1 genes FLT3 Signaling (1 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-2 family signaling Interleukin receptor SHC signaling FLT3 Signaling 1 genes IL-6-type cytokine receptor ligand interactions (1 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-6 family signaling IL-6-type cytokine receptor ligand interactions 1 genes Interleukin-1 processing (2 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-1 family signaling Interleukin-1 processing 2 genes Interleukin-2 signaling (1 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-2 family signaling Interleukin-2 signaling 1 genes Interleukin-36 pathway (1 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-1 family signaling Interleukin-36 pathway 1 genes Interleukin-38 signaling (1 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-1 family signaling Interleukin-38 signaling 1 genes PKR-mediated signaling (1 genes) Immune System Cytokine Signaling in Immune system Interferon Signaling Antiviral mechanism by IFN-stimulated genes PKR-mediated signaling 1 genes Regulation of signaling by CBL (1 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-3, Interleukin-5 and GM-CSF signaling Regulation of signaling by CBL 1 genes Growth hormone receptor signaling (1 genes) Immune System Cytokine Signaling in Immune system Prolactin receptor signaling Growth hormone receptor signaling 1 genes Interferon gamma signaling (5 genes) Immune System Cytokine Signaling in Immune system Interferon Signaling Interferon gamma signaling 5 genes Interleukin-7 signaling (1 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Interleukin-7 signaling 1 genes Negative regulation of FLT3 (1 genes) Immune System Cytokine Signaling in Immune system FLT3 Signaling Negative regulation of FLT3 1 genes Other interleukin signaling (3 genes) Immune System Cytokine Signaling in Immune system Signaling by Interleukins Other interleukin signaling 3 genes TNFs bind their physiological receptors (1 genes) Immune System Cytokine Signaling in Immune system TNFR2 non-canonical NF-kB pathway TNFs bind their physiological receptors 1 genes FLT3 Signaling (1 genes) Immune System Cytokine Signaling in Immune system FLT3 Signaling 1 genes TNFR2 non-canonical NF-kB pathway (1 genes) Immune System Cytokine Signaling in Immune system TNFR2 non-canonical NF-kB pathway 1 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Camk2a Gene Information Basic Information Ensembl ID: ENSMUSG00000024617 Description: calcium/calmodulin-dependent protein kinase II alpha [Source:MGI Symbol;Acc:MGI:88256] Location: 18:61058690-61121224 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Signaling by WNT Camk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000057897 Description: calcium/calmodulin-dependent protein kinase II%2C beta [Source:MGI Symbol;Acc:MGI:88257] Location: 11:5919644-6016362 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: kidney cell neuron enteroendocrine cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2d Gene Information Basic Information Ensembl ID: ENSMUSG00000053819 Description: calcium/calmodulin-dependent protein kinase II%2C delta [Source:MGI Symbol;Acc:MGI:1341265] Location: 3:126389951-126639975 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2g Gene Information Basic Information Ensembl ID: ENSMUSG00000021820 Description: calcium/calmodulin-dependent protein kinase II gamma [Source:MGI Symbol;Acc:MGI:88259] Location: 14:20784943-20844156 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Csf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000014599 Description: colony stimulating factor 1 (macrophage) [Source:MGI Symbol;Acc:MGI:1339753] Location: 3:107648364-107667785 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell basophil eosinophil Other: Cytokine Signaling in Immune system Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Csf1r Gene Information Basic Information Ensembl ID: ENSMUSG00000024621 Description: colony stimulating factor 1 receptor [Source:MGI Symbol;Acc:MGI:1339758] Location: 18:61233670-61265221 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell phagocyte myeloid cell antigen presenting cell T cell leukocyte macrophage monocyte stem cell myeloid progenitor cell Other: Cytokine Signaling in Immune system Edaradd Gene Information Basic Information Ensembl ID: ENSMUSG00000095105 Description: EDAR associated via death domain [Source:MGI Symbol;Acc:MGI:1931001] Location: 13:12487513-12535319 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pancreatic cell Other: Cytokine Signaling in Immune system Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Il1b Gene Information Basic Information Ensembl ID: ENSMUSG00000027398 Description: interleukin 1 beta [Source:MGI Symbol;Acc:MGI:96543] Location: 2:129206490-129213059 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell dendritic cell phagocyte granulocyte myeloid cell erythroid lineage cell T cell leukocyte macrophage Other: Cytokine Signaling in Immune system Innate Immune System Regulated Necrosis Il1rap Gene Information Basic Information Ensembl ID: ENSMUSG00000022514 Description: interleukin 1 receptor accessory protein [Source:MGI Symbol;Acc:MGI:104975] Location: 16:26400454-26548867 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell bipolar cell neuron Other: Cytokine Signaling in Immune system Protein-protein interactions at synapses Intracellular signaling by second messengers Il31ra Gene Information Basic Information Ensembl ID: ENSMUSG00000050377 Description: interleukin 31 receptor A [Source:MGI Symbol;Acc:MGI:2180511] Location: 13:112656432-112730894 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Irs2 Gene Information Basic Information Ensembl ID: ENSMUSG00000038894 Description: insulin receptor substrate 2 [Source:MGI Symbol;Acc:MGI:109334] Location: 8:11034681-11058458 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mural cell Other: Cytokine Signaling in Immune system MAPK family signaling cascades Signaling by Erythropoietin Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk8 Gene Information Basic Information Ensembl ID: ENSMUSG00000021936 Description: mitogen-activated protein kinase 8 [Source:MGI Symbol;Acc:MGI:1346861] Location: 14:33099855-33169115 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Cytokine Signaling in Immune system Innate Immune System Nfkb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028163 Description: nuclear factor of kappa light polypeptide gene enhancer in B cells 1%2C p105 [Source:MGI Symbol;Acc:MGI:97312] Location: 3:135290416-135397308 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system Prlr Gene Information Basic Information Ensembl ID: ENSMUSG00000005268 Description: prolactin receptor [Source:MGI Symbol;Acc:MGI:97763] Location: 15:10177324-10349266 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stem cell stromal cell adrenal cortical cell pancreatic cell luminal cell Other: Cytokine Signaling in Immune system Ptk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000059456 Description: PTK2 protein tyrosine kinase 2 beta [Source:MGI Symbol;Acc:MGI:104908] Location: 14:66390706-66518501 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell Specialized T cell neuron Other: Cytokine Signaling in Immune system Signal regulatory protein family interactions Signaling by Receptor Tyrosine Kinases Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Rps6ka1 Gene Information Basic Information Ensembl ID: ENSMUSG00000003644 Description: ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:104558] Location: 4:133574601-133615108 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Innate Immune System Sla Gene Information Basic Information Ensembl ID: ENSMUSG00000022372 Description: src-like adaptor [Source:MGI Symbol;Acc:MGI:104295] Location: 15:66652668-66703678 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell dendritic cell Other: Cytokine Signaling in Immune system Snca Gene Information Basic Information Ensembl ID: ENSMUSG00000025889 Description: synuclein%2C alpha [Source:MGI Symbol;Acc:MGI:1277151] Location: 6:60708559-60806839 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Stat3 Gene Information Basic Information Ensembl ID: ENSMUSG00000004040 Description: signal transducer and activator of transcription 3 [Source:MGI Symbol;Acc:MGI:103038] Location: 11:100775924-100830366 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Signaling by Non-Receptor Tyrosine Kinases Signaling by Receptor Tyrosine Kinases Stx1a Gene Information Basic Information Ensembl ID: ENSMUSG00000007207 Description: syntaxin 1A (brain) [Source:MGI Symbol;Acc:MGI:109355] Location: 5:135052336-135079954 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system LGI-ADAM interactions Tnf Gene Information Basic Information Ensembl ID: ENSMUSG00000024401 Description: tumor necrosis factor [Source:MGI Symbol;Acc:MGI:104798] Location: 17:35418357-35420983 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macrophage leukocyte Other: Cytokine Signaling in Immune system Death Receptor Signaling
DNA Double-Strand Break Repair Pathway Hierarchies & Genes Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (2 genes) DNA Repair DNA Double-Strand Break Repair DNA Double Strand Break Response Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks 2 genes	Eya2 Gene Information Basic Information Ensembl ID: ENSMUSG00000017897 Description: EYA transcriptional coactivator and phosphatase 2 [Source:MGI Symbol;Acc:MGI:109341] Location: 2:165436952-165613647 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: DNA Double-Strand Break Repair Mapk8 Gene Information Basic Information Ensembl ID: ENSMUSG00000021936 Description: mitogen-activated protein kinase 8 [Source:MGI Symbol;Acc:MGI:1346861] Location: 14:33099855-33169115 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Cytokine Signaling in Immune system Innate Immune System
DNA Replication Pre-Initiation Pathway Hierarchies & Genes Activation of the pre-replicative complex (1 genes) DNA Replication DNA Replication Pre-Initiation Assembly of the pre-replicative complex Activation of the pre-replicative complex 1 genes	Mcm6 Gene Information Basic Information Ensembl ID: ENSMUSG00000026355 Description: minichromosome maintenance complex component 6 [Source:MGI Symbol;Acc:MGI:1298227] Location: 1:128259327-128287401 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: erythroblast Other: DNA Replication Pre-Initiation Synthesis of DNA Cell Cycle, Mitotic
Death Receptor Signaling Pathway Hierarchies & Genes Axonal growth inhibition (RHOA activation) (1 genes) Signal Transduction Death Receptor Signaling p75 NTR receptor-mediated signalling p75NTR regulates axonogenesis Axonal growth inhibition (RHOA activation) 1 genes NF-kB is activated and signals survival (1 genes) Signal Transduction Death Receptor Signaling p75 NTR receptor-mediated signalling p75NTR signals via NF-kB NF-kB is activated and signals survival 1 genes NRAGE signals death through JNK (3 genes) Signal Transduction Death Receptor Signaling p75 NTR receptor-mediated signalling Cell death signalling via NRAGE, NRIF and NADE NRAGE signals death through JNK 3 genes NRIF signals cell death from the nucleus (1 genes) Signal Transduction Death Receptor Signaling p75 NTR receptor-mediated signalling Cell death signalling via NRAGE, NRIF and NADE NRIF signals cell death from the nucleus 1 genes Regulation of TNFR1 signaling (1 genes) Signal Transduction Death Receptor Signaling TNF signaling Regulation of TNFR1 signaling 1 genes TNFR1-induced proapoptotic signaling (1 genes) Signal Transduction Death Receptor Signaling TNF signaling TNFR1-induced proapoptotic signaling 1 genes TNFR1-mediated ceramide production (1 genes) Signal Transduction Death Receptor Signaling TNF signaling TNFR1-mediated ceramide production 1 genes	Arhgef7 Gene Information Basic Information Ensembl ID: ENSMUSG00000031511 Description: Rho guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1860493] Location: 8:11777721-11885219 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell smooth muscle cell Other: Signaling by GPCR Death Receptor Signaling Signaling by Receptor Tyrosine Kinases Lingo1 Gene Information Basic Information Ensembl ID: ENSMUSG00000049556 Description: leucine rich repeat and Ig domain containing 1 [Source:MGI Symbol;Acc:MGI:1915522] Location: 9:56525759-56703752 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Death Receptor Signaling Mapk8 Gene Information Basic Information Ensembl ID: ENSMUSG00000021936 Description: mitogen-activated protein kinase 8 [Source:MGI Symbol;Acc:MGI:1346861] Location: 14:33099855-33169115 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Cytokine Signaling in Immune system Innate Immune System Nfkb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028163 Description: nuclear factor of kappa light polypeptide gene enhancer in B cells 1%2C p105 [Source:MGI Symbol;Acc:MGI:97312] Location: 3:135290416-135397308 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Ngef Gene Information Basic Information Ensembl ID: ENSMUSG00000026259 Description: neuronal guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1858414] Location: 1:87404556-87501592 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Death Receptor Signaling Nervous system development Optn Gene Information Basic Information Ensembl ID: ENSMUSG00000026672 Description: optineurin [Source:MGI Symbol;Acc:MGI:1918898] Location: 2:5025453-5068862 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Macroautophagy Innate Immune System Membrane Trafficking Psen1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019969 Description: presenilin 1 [Source:MGI Symbol;Acc:MGI:1202717] Location: 12:83734926-83781973 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by NOTCH Death Receptor Signaling Smpd3 Gene Information Basic Information Ensembl ID: ENSMUSG00000031906 Description: sphingomyelin phosphodiesterase 3%2C neutral [Source:MGI Symbol;Acc:MGI:1927578] Location: 8:106979180-107064620 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell fibroblast osteoblast Other: Metabolism of lipids Death Receptor Signaling Tnf Gene Information Basic Information Ensembl ID: ENSMUSG00000024401 Description: tumor necrosis factor [Source:MGI Symbol;Acc:MGI:104798] Location: 17:35418357-35420983 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macrophage leukocyte Other: Cytokine Signaling in Immune system Death Receptor Signaling
Degradation of the extracellular matrix Pathway Hierarchies & Genes Activation of Matrix Metalloproteinases (10 genes) Extracellular matrix organization Degradation of the extracellular matrix 5 genes Collagen degradation 4 genes Activation of Matrix Metalloproteinases 1 genes Activation of Matrix Metalloproteinases (2 genes) Extracellular matrix organization Degradation of the extracellular matrix Collagen degradation Activation of Matrix Metalloproteinases 2 genes	Cd44 Gene Information Basic Information Ensembl ID: ENSMUSG00000005087 Description: CD44 antigen [Source:MGI Symbol;Acc:MGI:88338] Location: 2:102641486-102732010 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell phagocyte monocyte granulocyte neutrophil macrophage progenitor cell Other: Cell surface interactions at the vascular wall Integrin cell surface interactions Innate Immune System Col11a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027966 Description: collagen%2C type XI%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88446] Location: 3:113824189-114014367 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell Other: Degradation of the extracellular matrix Collagen formation Non-integrin membrane-ECM interactions Col18a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001435 Description: collagen%2C type XVIII%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88451] Location: 10:76888012-77002382 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stellate cell glial cell smooth muscle cell neuron epithelial cell Other: Degradation of the extracellular matrix Collagen formation Integrin cell surface interactions Col5a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026837 Description: collagen%2C type V%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88457] Location: 2:27776437-27929526 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell epithelial cell Other: Integrin cell surface interactions Degradation of the extracellular matrix Collagen formation Col8a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000068196 Description: collagen%2C type VIII%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88463] Location: 16:57444621-57575100 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell fibroblast glial cell epithelial cell Other: Degradation of the extracellular matrix Collagen formation Integrin cell surface interactions Dcn Gene Information Basic Information Ensembl ID: ENSMUSG00000019929 Description: decorin [Source:MGI Symbol;Acc:MGI:94872] Location: 10:97315471-97354005 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell pericyte stem cell stromal cell epithelial cell dendritic cell Other: Degradation of the extracellular matrix ECM proteoglycans Metabolism of carbohydrates and carbohydrate derivatives Fbn2 Gene Information Basic Information Ensembl ID: ENSMUSG00000024598 Description: fibrillin 2 [Source:MGI Symbol;Acc:MGI:95490] Location: 18:58141695-58343559 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast embryonic cell stromal cell Other: Degradation of the extracellular matrix Elastic fibre formation Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Mmp14 Gene Information Basic Information Ensembl ID: ENSMUSG00000000957 Description: matrix metallopeptidase 14 (membrane-inserted) [Source:MGI Symbol;Acc:MGI:101900] Location: 14:54669069-54682821 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast bone cell smooth muscle cell epithelial cell Other: Degradation of the extracellular matrix Signaling by TGFB family members Mmp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031740 Description: matrix metallopeptidase 2 [Source:MGI Symbol;Acc:MGI:97009] Location: 8:93553919-93580048 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Degradation of the extracellular matrix Signaling by Nuclear Receptors Nervous system development Spock3 Gene Information Basic Information Ensembl ID: ENSMUSG00000054162 Description: sparc/osteonectin%2C cwcv and kazal-like domains proteoglycan 3 [Source:MGI Symbol;Acc:MGI:1920152] Location: 8:63404043-63810137 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron neuron epithelial cell Other: Degradation of the extracellular matrix Spp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029304 Description: secreted phosphoprotein 1 [Source:MGI Symbol;Acc:MGI:98389] Location: 5:104582984-104588916 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte glial cell epithelial cell fibroblast hepatocyte Other: Signaling by Receptor Tyrosine Kinases Degradation of the extracellular matrix Integrin cell surface interactions
Dissolution of Fibrin Clot Pathway Hierarchies & Genes Dissolution of Fibrin Clot (1 genes) Hemostasis Dissolution of Fibrin Clot 1 genes	Serpinb8 Gene Information Basic Information Ensembl ID: ENSMUSG00000026315 Description: serine (or cysteine) peptidase inhibitor%2C clade B%2C member 8 [Source:MGI Symbol;Acc:MGI:894657] Location: 1:107517736-107538214 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Dissolution of Fibrin Clot
ECM proteoglycans Pathway Hierarchies & Genes ECM proteoglycans (8 genes) Extracellular matrix organization ECM proteoglycans 8 genes	Col5a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026837 Description: collagen%2C type V%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88457] Location: 2:27776437-27929526 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell epithelial cell Other: Integrin cell surface interactions Degradation of the extracellular matrix Collagen formation Dcn Gene Information Basic Information Ensembl ID: ENSMUSG00000019929 Description: decorin [Source:MGI Symbol;Acc:MGI:94872] Location: 10:97315471-97354005 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell pericyte stem cell stromal cell epithelial cell dendritic cell Other: Degradation of the extracellular matrix ECM proteoglycans Metabolism of carbohydrates and carbohydrate derivatives Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Itga8 Gene Information Basic Information Ensembl ID: ENSMUSG00000026768 Description: integrin alpha 8 [Source:MGI Symbol;Acc:MGI:109442] Location: 2:12111443-12306733 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast smooth muscle cell epithelial cell mesenchymal stem cell Other: Elastic fibre formation Integrin cell surface interactions ECM proteoglycans Itgax Gene Information Basic Information Ensembl ID: ENSMUSG00000030789 Description: integrin alpha X [Source:MGI Symbol;Acc:MGI:96609] Location: 7:127728719-127749829 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell phagocyte macrophage dendritic cell Other: Innate Immune System Cell surface interactions at the vascular wall Integrin cell surface interactions Tnc Gene Information Basic Information Ensembl ID: ENSMUSG00000028364 Description: tenascin C [Source:MGI Symbol;Acc:MGI:101922] Location: 4:63878022-63965252 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell fibroblast epithelial cell glial cell smooth muscle cell Other: Integrin cell surface interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Tnr Gene Information Basic Information Ensembl ID: ENSMUSG00000015829 Description: tenascin R [Source:MGI Symbol;Acc:MGI:99516] Location: 1:159351339-159759299 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: oligodendrocyte precursor cell retina cell Other: ECM proteoglycans Vcan Gene Information Basic Information Ensembl ID: ENSMUSG00000021614 Description: versican [Source:MGI Symbol;Acc:MGI:102889] Location: 13:89803431-89890628 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast glial cell oligodendrocyte precursor cell epithelial cell monocyte pericyte mural cell Other: ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification
Elastic fibre formation Pathway Hierarchies & Genes Molecules associated with elastic fibres (7 genes) Extracellular matrix organization Elastic fibre formation Molecules associated with elastic fibres 7 genes	Bmp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000021835 Description: bone morphogenetic protein 4 [Source:MGI Symbol;Acc:MGI:88180] Location: 14:46620977-46628126 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stem cell fibroblast epithelial cell smooth muscle cell ectodermal cell endothelial cell mesodermal cell Other: Elastic fibre formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Fbln2 Gene Information Basic Information Ensembl ID: ENSMUSG00000064080 Description: fibulin 2 [Source:MGI Symbol;Acc:MGI:95488] Location: 6:91189437-91249522 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stem cell glial cell smooth muscle cell Other: Elastic fibre formation Fbn2 Gene Information Basic Information Ensembl ID: ENSMUSG00000024598 Description: fibrillin 2 [Source:MGI Symbol;Acc:MGI:95490] Location: 18:58141695-58343559 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast embryonic cell stromal cell Other: Degradation of the extracellular matrix Elastic fibre formation Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Itga8 Gene Information Basic Information Ensembl ID: ENSMUSG00000026768 Description: integrin alpha 8 [Source:MGI Symbol;Acc:MGI:109442] Location: 2:12111443-12306733 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast smooth muscle cell epithelial cell mesenchymal stem cell Other: Elastic fibre formation Integrin cell surface interactions ECM proteoglycans Ltbp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001870 Description: latent transforming growth factor beta binding protein 1 [Source:MGI Symbol;Acc:MGI:109151] Location: 17:75312563-75699507 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Elastic fibre formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Tgfb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000002603 Description: transforming growth factor%2C beta 1 [Source:MGI Symbol;Acc:MGI:98725] Location: 7:25386427-25404502 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell hematopoietic stem cell phagocyte monocyte leukocyte megakaryocyte Other: Cell surface interactions at the vascular wall Non-integrin membrane-ECM interactions Elastic fibre formation
Factors involved in megakaryocyte development and platelet production Pathway Hierarchies & Genes Kinesins (6 genes) Hemostasis Factors involved in megakaryocyte development and platelet production 3 genes Kinesins 3 genes	Cenpe Gene Information Basic Information Ensembl ID: ENSMUSG00000045328 Description: centromere protein E [Source:MGI Symbol;Acc:MGI:1098230] Location: 3:134918298-134979372 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Cell Cycle, Mitotic Dock5 Gene Information Basic Information Ensembl ID: ENSMUSG00000044447 Description: dedicator of cytokinesis 5 [Source:MGI Symbol;Acc:MGI:2652871] Location: 14:67989584-68170891 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell fibroblast stromal cell bone cell Other: Factors involved in megakaryocyte development and platelet production Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Gata3 Gene Information Basic Information Ensembl ID: ENSMUSG00000015619 Description: GATA binding protein 3 [Source:MGI Symbol;Acc:MGI:95663] Location: 2:9861889-9894845 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell epithelial cell stem cell CD4+ T cell innate lymphoid cell developing T cell mesangial cell Other: Post-translational protein modification RNA Polymerase II Transcription Signaling by Nuclear Receptors Kif11 Gene Information Basic Information Ensembl ID: ENSMUSG00000012443 Description: kinesin family member 11 [Source:MGI Symbol;Acc:MGI:1098231] Location: 19:37364851-37410307 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: hematopoietic cell Other: Adaptive Immune System Membrane Trafficking Factors involved in megakaryocyte development and platelet production Kif5a Gene Information Basic Information Ensembl ID: ENSMUSG00000074657 Description: kinesin family member 5A [Source:MGI Symbol;Acc:MGI:109564] Location: 10:127061565-127099217 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Zfpm2 Gene Information Basic Information Ensembl ID: ENSMUSG00000022306 Description: zinc finger protein%2C multitype 2 [Source:MGI Symbol;Acc:MGI:1334444] Location: 15:40518431-40967988 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell neuron epithelial cell retina cell Other: Factors involved in megakaryocyte development and platelet production
Fibronectin matrix formation Pathway Hierarchies & Genes Fibronectin matrix formation (2 genes) Extracellular matrix organization Fibronectin matrix formation 2 genes	Col5a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026837 Description: collagen%2C type V%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88457] Location: 2:27776437-27929526 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell epithelial cell Other: Integrin cell surface interactions Degradation of the extracellular matrix Collagen formation Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation
Gastrulation Pathway Hierarchies & Genes Specification of the neural plate border (1 genes) Developmental Biology Gastrulation Specification of the neural plate border 1 genes	Tfap2b Gene Information Basic Information Ensembl ID: ENSMUSG00000025927 Description: transcription factor AP-2 beta [Source:MGI Symbol;Acc:MGI:104672] Location: 1:19279138-19308800 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stem cell interneuron progenitor cell Other: RNA Polymerase II Transcription Gastrulation
Gene Silencing by RNA Pathway Hierarchies & Genes Transcriptional regulation by small RNAs (1 genes) Gene expression (Transcription) Gene Silencing by RNA Transcriptional regulation by small RNAs 1 genes	Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress
Glycosphingolipid transport Pathway Hierarchies & Genes Glycosphingolipid transport (1 genes) Transport of small molecules Glycosphingolipid transport 1 genes	Esyt3 Gene Information Basic Information Ensembl ID: ENSMUSG00000037681 Description: extended synaptotagmin-like protein 3 [Source:MGI Symbol;Acc:MGI:1098699] Location: 9:99192016-99240610 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Glycosphingolipid transport
Innate Immune System Pathway Hierarchies & Genes Neutrophil degranulation (1 genes) Immune System Innate Immune System Cytosolic sensors of pathogen-associated DNA ZBP1(DAI) mediated induction of type I IFNs RIP-mediated NFkB activation via ZBP1 Toll-like Receptor Cascades Toll Like Receptor 3 (TLR3) Cascade MAP kinase activation MAP3K8 (TPL2)-dependent MAPK1/3 activation DDX58/IFIH1-mediated induction of interferon-alpha/beta TRAF6 mediated NF-kB activation Fc epsilon receptor (FCERI) signaling FCERI mediated NF-kB activation C-type lectin receptors (CLRs) CLEC7A (Dectin-1) signaling Neutrophil degranulation 1 genes Neutrophil degranulation (4 genes) Immune System Innate Immune System Toll-like Receptor Cascades Toll Like Receptor 3 (TLR3) Cascade MAP kinase activation MAPK targets/ Nuclear events mediated by MAP kinases Activation of the AP-1 family of transcription factors Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation 1 genes Fc epsilon receptor (FCERI) signaling 1 genes FCERI mediated MAPK activation 1 genes Neutrophil degranulation 1 genes Dectin-2 family (2 genes) Immune System Innate Immune System Fcgamma receptor (FCGR) dependent phagocytosis FCGR activation 1 genes DAP12 interactions DAP12 signaling C-type lectin receptors (CLRs) Dectin-2 family 1 genes Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 (2 genes) Immune System Innate Immune System Toll-like Receptor Cascades Toll Like Receptor 4 (TLR4) Cascade MyD88-independent TLR4 cascade TRIF (TICAM1)-mediated TLR4 signaling Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 2 genes Role of LAT2/NTAL/LAB on calcium mobilization (4 genes) Immune System Innate Immune System Fcgamma receptor (FCGR) dependent phagocytosis Role of phospholipids in phagocytosis 2 genes DAP12 interactions DAP12 signaling Fc epsilon receptor (FCERI) signaling 1 genes Role of LAT2/NTAL/LAB on calcium mobilization 1 genes Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (1 genes) Immune System Innate Immune System Toll-like Receptor Cascades Toll Like Receptor 4 (TLR4) Cascade MyD88-independent TLR4 cascade TRIF (TICAM1)-mediated TLR4 signaling Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) 1 genes CLEC7A (Dectin-1) induces NFAT activation (1 genes) Immune System Innate Immune System Fc epsilon receptor (FCERI) signaling FCERI mediated Ca+2 mobilization C-type lectin receptors (CLRs) CLEC7A (Dectin-1) signaling CLEC7A (Dectin-1) induces NFAT activation 1 genes MAPK targets/ Nuclear events mediated by MAP kinases (1 genes) Immune System Innate Immune System Toll-like Receptor Cascades Toll Like Receptor 3 (TLR3) Cascade MAP kinase activation MAPK targets/ Nuclear events mediated by MAP kinases 1 genes Neutrophil degranulation (1 genes) Immune System Innate Immune System Complement cascade Initial triggering of complement Alternative complement activation Neutrophil degranulation 1 genes Beta defensins (1 genes) Immune System Innate Immune System Antimicrobial peptides Defensins Beta defensins 1 genes CLEC7A/inflammasome pathway (1 genes) Immune System Innate Immune System C-type lectin receptors (CLRs) CLEC7A (Dectin-1) signaling CLEC7A/inflammasome pathway 1 genes Neutrophil degranulation (1 genes) Immune System Innate Immune System Toll-like Receptor Cascades Regulation of TLR by endogenous ligand Neutrophil degranulation 1 genes Neutrophil degranulation (2 genes) Immune System Innate Immune System Complement cascade Regulation of Complement cascade Neutrophil degranulation 2 genes The NLRP1 inflammasome (2 genes) Immune System Innate Immune System Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Inflammasomes The NLRP1 inflammasome 2 genes FCERI mediated NF-kB activation (1 genes) Immune System Innate Immune System Fc epsilon receptor (FCERI) signaling FCERI mediated NF-kB activation 1 genes LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (1 genes) Immune System Innate Immune System Cytosolic sensors of pathogen-associated DNA LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production 1 genes NOD1/2 Signaling Pathway (1 genes) Immune System Innate Immune System Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways NOD1/2 Signaling Pathway 1 genes Neutrophil degranulation (3 genes) Immune System Innate Immune System ROS and RNS production in phagocytes 2 genes Neutrophil degranulation 1 genes Regulation of actin dynamics for phagocytic cup formation (1 genes) Immune System Innate Immune System Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation 1 genes Toll Like Receptor 4 (TLR4) Cascade (1 genes) Immune System Innate Immune System Toll-like Receptor Cascades Toll Like Receptor 4 (TLR4) Cascade 1 genes Trafficking and processing of endosomal TLR (1 genes) Immune System Innate Immune System Toll-like Receptor Cascades Trafficking and processing of endosomal TLR 1 genes Neutrophil degranulation (11 genes) Immune System Innate Immune System Neutrophil degranulation 11 genes	Atp6v0a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019302 Description: ATPase%2C H+ transporting%2C lysosomal V0 subunit A1 [Source:MGI Symbol;Acc:MGI:103286] Location: 11:100900278-100954545 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte eosinophil Other: Innate Immune System Signaling by Receptor Tyrosine Kinases Iron uptake and transport Atp6v1a Gene Information Basic Information Ensembl ID: ENSMUSG00000052459 Description: ATPase%2C H+ transporting%2C lysosomal V1 subunit A [Source:MGI Symbol;Acc:MGI:1201780] Location: 16:43905765-43960068 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Cellular responses to stress Signaling by Receptor Tyrosine Kinases Baiap2 Gene Information Basic Information Ensembl ID: ENSMUSG00000025372 Description: brain-specific angiogenesis inhibitor 1-associated protein 2 [Source:MGI Symbol;Acc:MGI:2137336] Location: 11:119833589-119897608 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Innate Immune System Signaling by Receptor Tyrosine Kinases Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Bcl2 Gene Information Basic Information Ensembl ID: ENSMUSG00000057329 Description: B cell leukemia/lymphoma 2 [Source:MGI Symbol;Acc:MGI:88138] Location: 1:106465908-106642004 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Innate Immune System Bcl2l1 Gene Information Basic Information Ensembl ID: ENSMUSG00000007659 Description: BCL2-like 1 [Source:MGI Symbol;Acc:MGI:88139] Location: 2:152622588-152673648 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Innate Immune System MAPK family signaling cascades C3 Gene Information Basic Information Ensembl ID: ENSMUSG00000024164 Description: complement component 3 [Source:MGI Symbol;Acc:MGI:88227] Location: 17:57510970-57535136 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell fibroblast stellate cell stem cell endothelial cell stromal cell epithelial cell hepatocyte Other: Adaptive Immune System Innate Immune System Signaling by GPCR C3ar1 Gene Information Basic Information Ensembl ID: ENSMUSG00000040552 Description: complement component 3a receptor 1 [Source:MGI Symbol;Acc:MGI:1097680] Location: 6:122824097-122833120 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte basophil T cell monocyte macrophage leukocyte microglia Other: Innate Immune System Signaling by GPCR C5ar1 Gene Information Basic Information Ensembl ID: ENSMUSG00000049130 Description: complement component 5a receptor 1 [Source:MGI Symbol;Acc:MGI:88232] Location: 7:15980668-15993465 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell phagocyte granulocyte myeloid cell T cell monocyte macrophage leukocyte Other: Innate Immune System Signaling by GPCR Ccr6 Gene Information Basic Information Ensembl ID: ENSMUSG00000040899 Description: C-C motif chemokine receptor 6 [Source:MGI Symbol;Acc:MGI:1333797] Location: 17:8454875-8475973 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: memory B cell innate lymphoid cell Other: Innate Immune System Signaling by GPCR Cd247 Gene Information Basic Information Ensembl ID: ENSMUSG00000005763 Description: CD247 antigen [Source:MGI Symbol;Acc:MGI:88334] Location: 1:165616250-165704846 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell CD4+ T cell T cell hematopoietic cell Other: Adaptive Immune System Innate Immune System Cd36 Gene Information Basic Information Ensembl ID: ENSMUSG00000002944 Description: CD36 molecule [Source:MGI Symbol;Acc:MGI:107899] Location: 5:17986688-18093799 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macrophage Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Cd44 Gene Information Basic Information Ensembl ID: ENSMUSG00000005087 Description: CD44 antigen [Source:MGI Symbol;Acc:MGI:88338] Location: 2:102641486-102732010 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell phagocyte monocyte granulocyte neutrophil macrophage progenitor cell Other: Cell surface interactions at the vascular wall Integrin cell surface interactions Innate Immune System Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Dnm1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026825 Description: dynamin 1 [Source:MGI Symbol;Acc:MGI:107384] Location: 2:32198483-32243350 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Innate Immune System Membrane Trafficking Fpr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000045551 Description: formyl peptide receptor 1 [Source:MGI Symbol;Acc:MGI:107443] Location: 17:18096733-18104202 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell mast cell neutrophil Other: Innate Immune System Signaling by GPCR Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Il1b Gene Information Basic Information Ensembl ID: ENSMUSG00000027398 Description: interleukin 1 beta [Source:MGI Symbol;Acc:MGI:96543] Location: 2:129206490-129213059 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell dendritic cell phagocyte granulocyte myeloid cell erythroid lineage cell T cell leukocyte macrophage Other: Cytokine Signaling in Immune system Innate Immune System Regulated Necrosis Itch Gene Information Basic Information Ensembl ID: ENSMUSG00000027598 Description: itchy%2C E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1202301] Location: 2:154975429-155068775 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Signaling by NOTCH Innate Immune System Itgax Gene Information Basic Information Ensembl ID: ENSMUSG00000030789 Description: integrin alpha X [Source:MGI Symbol;Acc:MGI:96609] Location: 7:127728719-127749829 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell phagocyte macrophage dendritic cell Other: Innate Immune System Cell surface interactions at the vascular wall Integrin cell surface interactions Lgmn Gene Information Basic Information Ensembl ID: ENSMUSG00000021190 Description: legumain [Source:MGI Symbol;Acc:MGI:1330838] Location: 12:102360343-102406072 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell phagocyte monocyte erythroid progenitor cell antigen presenting cell T cell macrophage leukocyte epithelial cell Other: Adaptive Immune System Innate Immune System Lilra5 Gene Information Basic Information Ensembl ID: ENSMUSG00000070873 Description: leukocyte immunoglobulin-like receptor%2C subfamily A (with TM domain)%2C member 5 [Source:MGI Symbol;Acc:MGI:3647196] Location: 7:4240753-4246462 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte Other: Innate Immune System Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk8 Gene Information Basic Information Ensembl ID: ENSMUSG00000021936 Description: mitogen-activated protein kinase 8 [Source:MGI Symbol;Acc:MGI:1346861] Location: 14:33099855-33169115 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Cytokine Signaling in Immune system Innate Immune System Nfasc Gene Information Basic Information Ensembl ID: ENSMUSG00000026442 Description: neurofascin [Source:MGI Symbol;Acc:MGI:104753] Location: 1:132492428-132669535 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron bipolar cell astrocyte Other: Innate Immune System Nervous system development Nfatc2 Gene Information Basic Information Ensembl ID: ENSMUSG00000027544 Description: nuclear factor of activated T cells%2C cytoplasmic%2C calcineurin dependent 2 [Source:MGI Symbol;Acc:MGI:102463] Location: 2:168318330-168443577 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: astrocyte Other: Adaptive Immune System Innate Immune System Nfkb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028163 Description: nuclear factor of kappa light polypeptide gene enhancer in B cells 1%2C p105 [Source:MGI Symbol;Acc:MGI:97312] Location: 3:135290416-135397308 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Nos1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029361 Description: nitric oxide synthase 1%2C neuronal [Source:MGI Symbol;Acc:MGI:97360] Location: 5:117919097-118096905 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macula densa cell Other: Innate Immune System Platelet homeostasis Cardiac conduction Optn Gene Information Basic Information Ensembl ID: ENSMUSG00000026672 Description: optineurin [Source:MGI Symbol;Acc:MGI:1918898] Location: 2:5025453-5068862 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Macroautophagy Innate Immune System Membrane Trafficking Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Plpp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000070366 Description: phospholipid phosphatase 4 [Source:MGI Symbol;Acc:MGI:2685936] Location: 7:128858755-128993136 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: oligodendrocyte precursor cell Other: Innate Immune System Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system Prkce Gene Information Basic Information Ensembl ID: ENSMUSG00000045038 Description: protein kinase C%2C epsilon [Source:MGI Symbol;Acc:MGI:97599] Location: 17:86475213-86965347 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by GPCR Platelet activation, signaling and aggregation Prkcq Gene Information Basic Information Ensembl ID: ENSMUSG00000026778 Description: protein kinase C%2C theta [Source:MGI Symbol;Acc:MGI:97601] Location: 2:11176919-11306033 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell CD8+ T cell Specialized T cell Other: Apoptosis Adaptive Immune System Innate Immune System Psen1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019969 Description: presenilin 1 [Source:MGI Symbol;Acc:MGI:1202717] Location: 12:83734926-83781973 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by NOTCH Death Receptor Signaling Ptafr Gene Information Basic Information Ensembl ID: ENSMUSG00000056529 Description: platelet-activating factor receptor [Source:MGI Symbol;Acc:MGI:106066] Location: 4:132291378-132309994 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell granulocyte T cell Other: Innate Immune System Signaling by GPCR Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Ptprc Gene Information Basic Information Ensembl ID: ENSMUSG00000026395 Description: protein tyrosine phosphatase receptor type C [Source:MGI Symbol;Acc:MGI:97810] Location: 1:137990599-138103446 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell phagocyte monocyte CD8+ T cell T cell Specialized T cell leukocyte lymphocyte hematopoietic cell myeloid cell immune cell Naive B cell epithelial cell Follicular B cell hematopoietic stem cell memory B cell Other: Innate Immune System Adaptive Immune System Nervous system development Qpct Gene Information Basic Information Ensembl ID: ENSMUSG00000024084 Description: glutaminyl-peptide cyclotransferase (glutaminyl cyclase) [Source:MGI Symbol;Acc:MGI:1917786] Location: 17:79359335-79397807 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron oligodendrocyte precursor cell dendritic cell Other: Innate Immune System Rab3a Gene Information Basic Information Ensembl ID: ENSMUSG00000031840 Description: RAB3A%2C member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97843] Location: 8:71207328-71211323 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Innate Immune System Membrane Trafficking Rap1a Gene Information Basic Information Ensembl ID: ENSMUSG00000068798 Description: RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852] Location: 3:105634583-105708652 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell monocyte muscle cell dendritic cell plasma cell megakaryocyte Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Rps6ka1 Gene Information Basic Information Ensembl ID: ENSMUSG00000003644 Description: ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:104558] Location: 4:133574601-133615108 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Innate Immune System Tlr4 Gene Information Basic Information Ensembl ID: ENSMUSG00000039005 Description: toll-like receptor 4 [Source:MGI Symbol;Acc:MGI:96824] Location: 4:66745821-66848521 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte Other: Apoptosis Innate Immune System Cellular responses to stress
Inositol phosphate metabolism Pathway Hierarchies & Genes Synthesis of IP3 and IP4 in the cytosol (4 genes) Metabolism Inositol phosphate metabolism Synthesis of IP3 and IP4 in the cytosol 4 genes	Itpka Gene Information Basic Information Ensembl ID: ENSMUSG00000027296 Description: inositol 1%2C4%2C5-trisphosphate 3-kinase A [Source:MGI Symbol;Acc:MGI:1333822] Location: 2:119572818-119581744 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Inositol phosphate metabolism Plcb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000051177 Description: phospholipase C%2C beta 1 [Source:MGI Symbol;Acc:MGI:97613] Location: 2:134627987-135317178 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell epithelial cell endothelial cell adipocyte Other: Transmission across Chemical Synapses Inositol phosphate metabolism Integration of energy metabolism Plcb4 Gene Information Basic Information Ensembl ID: ENSMUSG00000039943 Description: phospholipase C%2C beta 4 [Source:MGI Symbol;Acc:MGI:107464] Location: 2:135500931-135856513 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell neuron epithelial cell Other: Inositol phosphate metabolism Signaling by GPCR Pten Gene Information Basic Information Ensembl ID: ENSMUSG00000013663 Description: phosphatase and tensin homolog [Source:MGI Symbol;Acc:MGI:109583] Location: 19:32734897-32803560 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Inositol phosphate metabolism Metabolism of lipids
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Pathway Hierarchies & Genes Insertion of tail-anchored proteins into the endoplasmic reticulum membrane (1 genes) Protein localization Insertion of tail-anchored proteins into the endoplasmic reticulum membrane 1 genes	Stx1a Gene Information Basic Information Ensembl ID: ENSMUSG00000007207 Description: syntaxin 1A (brain) [Source:MGI Symbol;Acc:MGI:109355] Location: 5:135052336-135079954 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system LGI-ADAM interactions
Integration of energy metabolism Pathway Hierarchies & Genes Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (1 genes) Metabolism Integration of energy metabolism Regulation of insulin secretion Free fatty acids regulate insulin secretion Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion 1 genes Intracellular metabolism of fatty acids regulates insulin secretion (1 genes) Metabolism Integration of energy metabolism Regulation of insulin secretion Free fatty acids regulate insulin secretion Intracellular metabolism of fatty acids regulates insulin secretion 1 genes Adrenaline,noradrenaline inhibits insulin secretion (2 genes) Metabolism Integration of energy metabolism Regulation of insulin secretion Adrenaline,noradrenaline inhibits insulin secretion 2 genes Glucagon-like Peptide-1 (GLP1) regulates insulin secretion (7 genes) Metabolism Integration of energy metabolism Regulation of insulin secretion Glucagon-like Peptide-1 (GLP1) regulates insulin secretion 7 genes AMPK inhibits chREBP transcriptional activation activity (1 genes) Metabolism Integration of energy metabolism AMPK inhibits chREBP transcriptional activation activity 1 genes Glucagon signaling in metabolic regulation (1 genes) Metabolism Integration of energy metabolism Glucagon signaling in metabolic regulation 1 genes Regulation of insulin secretion (5 genes) Metabolism Integration of energy metabolism Regulation of insulin secretion 5 genes	Adcy5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022840 Description: adenylate cyclase 5 [Source:MGI Symbol;Acc:MGI:99673] Location: 16:34975247-35126108 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell projection neuron Other: Transmission across Chemical Synapses Integration of energy metabolism Signaling by GPCR Adra2c Gene Information Basic Information Ensembl ID: ENSMUSG00000045318 Description: adrenergic receptor%2C alpha 2c [Source:MGI Symbol;Acc:MGI:87936] Location: 5:35435663-35439107 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Integration of energy metabolism Signaling by GPCR Surfactant metabolism Cacna1a Gene Information Basic Information Ensembl ID: ENSMUSG00000034656 Description: calcium channel%2C voltage-dependent%2C P/Q type%2C alpha 1A subunit [Source:MGI Symbol;Acc:MGI:109482] Location: 8:85065268-85366875 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron endocrine cell interneuron Other: Transmission across Chemical Synapses Integration of energy metabolism Cacna1c Gene Information Basic Information Ensembl ID: ENSMUSG00000051331 Description: calcium channel%2C voltage-dependent%2C L type%2C alpha 1C subunit [Source:MGI Symbol;Acc:MGI:103013] Location: 6:118564201-119173851 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte fibroblast adrenal cortical cell theca cell Other: Integration of energy metabolism Cardiac conduction Cacna1d Gene Information Basic Information Ensembl ID: ENSMUSG00000015968 Description: calcium channel%2C voltage-dependent%2C L type%2C alpha 1D subunit [Source:MGI Symbol;Acc:MGI:88293] Location: 14:29761896-30213412 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte epithelial cell interneuron Other: Integration of energy metabolism Cacna1e Gene Information Basic Information Ensembl ID: ENSMUSG00000004110 Description: calcium channel%2C voltage-dependent%2C R type%2C alpha 1E subunit [Source:MGI Symbol;Acc:MGI:106217] Location: 1:154266477-154760247 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell excitatory neuron Other: Transmission across Chemical Synapses Integration of energy metabolism Cd36 Gene Information Basic Information Ensembl ID: ENSMUSG00000002944 Description: CD36 molecule [Source:MGI Symbol;Acc:MGI:107899] Location: 5:17986688-18093799 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macrophage Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Gcgr Gene Information Basic Information Ensembl ID: ENSMUSG00000025127 Description: glucagon receptor [Source:MGI Symbol;Acc:MGI:99572] Location: 11:120421525-120429812 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Integration of energy metabolism Signaling by GPCR Glp1r Gene Information Basic Information Ensembl ID: ENSMUSG00000024027 Description: glucagon-like peptide 1 receptor [Source:MGI Symbol;Acc:MGI:99571] Location: 17:31120791-31159765 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Integration of energy metabolism Signaling by GPCR Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Kcnc2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035681 Description: potassium voltage gated channel%2C Shaw-related subfamily%2C member 2 [Source:MGI Symbol;Acc:MGI:96668] Location: 10:112107026-112302929 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron neuron epithelial cell Other: Potassium Channels Integration of energy metabolism Kcng2 Gene Information Basic Information Ensembl ID: ENSMUSG00000059852 Description: potassium voltage-gated channel%2C subfamily G%2C member 2 [Source:MGI Symbol;Acc:MGI:3694646] Location: 18:80337761-80407469 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Potassium Channels Integration of energy metabolism Kcns3 Gene Information Basic Information Ensembl ID: ENSMUSG00000043673 Description: potassium voltage-gated channel%2C delayed-rectifier%2C subfamily S%2C member 3 [Source:MGI Symbol;Acc:MGI:1098804] Location: 12:11140203-11201057 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Integration of energy metabolism Plcb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000051177 Description: phospholipase C%2C beta 1 [Source:MGI Symbol;Acc:MGI:97613] Location: 2:134627987-135317178 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell epithelial cell endothelial cell adipocyte Other: Transmission across Chemical Synapses Inositol phosphate metabolism Integration of energy metabolism Prkaa2 Gene Information Basic Information Ensembl ID: ENSMUSG00000028518 Description: protein kinase%2C AMP-activated%2C alpha 2 catalytic subunit [Source:MGI Symbol;Acc:MGI:1336173] Location: 4:104887071-104967087 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Macroautophagy Integration of energy metabolism MTOR signalling Rap1a Gene Information Basic Information Ensembl ID: ENSMUSG00000068798 Description: RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852] Location: 3:105634583-105708652 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell monocyte muscle cell dendritic cell plasma cell megakaryocyte Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Rapgef4 Gene Information Basic Information Ensembl ID: ENSMUSG00000049044 Description: Rap guanine nucleotide exchange factor (GEF) 4 [Source:MGI Symbol;Acc:MGI:1917723] Location: 2:71811584-72087818 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell neuron adrenal cortical cell Other: Adaptive Immune System Integration of energy metabolism Integrin signaling Slc2a2 Gene Information Basic Information Ensembl ID: ENSMUSG00000027690 Description: solute carrier family 2 (facilitated glucose transporter)%2C member 2 [Source:MGI Symbol;Acc:MGI:1095438] Location: 3:28752052-28785508 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Integration of energy metabolism SLC-mediated transmembrane transport Intestinal absorption
Integrin cell surface interactions Pathway Hierarchies & Genes Integrin cell surface interactions (11 genes) Extracellular matrix organization Integrin cell surface interactions 11 genes	Cd44 Gene Information Basic Information Ensembl ID: ENSMUSG00000005087 Description: CD44 antigen [Source:MGI Symbol;Acc:MGI:88338] Location: 2:102641486-102732010 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell phagocyte monocyte granulocyte neutrophil macrophage progenitor cell Other: Cell surface interactions at the vascular wall Integrin cell surface interactions Innate Immune System Col18a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001435 Description: collagen%2C type XVIII%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88451] Location: 10:76888012-77002382 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stellate cell glial cell smooth muscle cell neuron epithelial cell Other: Degradation of the extracellular matrix Collagen formation Integrin cell surface interactions Col5a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026837 Description: collagen%2C type V%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88457] Location: 2:27776437-27929526 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell epithelial cell Other: Integrin cell surface interactions Degradation of the extracellular matrix Collagen formation Col8a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000068196 Description: collagen%2C type VIII%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88463] Location: 16:57444621-57575100 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell fibroblast glial cell epithelial cell Other: Degradation of the extracellular matrix Collagen formation Integrin cell surface interactions Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Icam5 Gene Information Basic Information Ensembl ID: ENSMUSG00000032174 Description: intercellular adhesion molecule 5%2C telencephalin [Source:MGI Symbol;Acc:MGI:109430] Location: 9:20943369-20950332 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Integrin cell surface interactions Itga8 Gene Information Basic Information Ensembl ID: ENSMUSG00000026768 Description: integrin alpha 8 [Source:MGI Symbol;Acc:MGI:109442] Location: 2:12111443-12306733 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast smooth muscle cell epithelial cell mesenchymal stem cell Other: Elastic fibre formation Integrin cell surface interactions ECM proteoglycans Itgax Gene Information Basic Information Ensembl ID: ENSMUSG00000030789 Description: integrin alpha X [Source:MGI Symbol;Acc:MGI:96609] Location: 7:127728719-127749829 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell phagocyte macrophage dendritic cell Other: Innate Immune System Cell surface interactions at the vascular wall Integrin cell surface interactions Jam3 Gene Information Basic Information Ensembl ID: ENSMUSG00000031990 Description: junction adhesion molecule 3 [Source:MGI Symbol;Acc:MGI:1933825] Location: 9:27008680-27066717 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell glial cell muscle cell schwann cell dendritic cell Other: Cell surface interactions at the vascular wall Integrin cell surface interactions Spp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029304 Description: secreted phosphoprotein 1 [Source:MGI Symbol;Acc:MGI:98389] Location: 5:104582984-104588916 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte glial cell epithelial cell fibroblast hepatocyte Other: Signaling by Receptor Tyrosine Kinases Degradation of the extracellular matrix Integrin cell surface interactions Tnc Gene Information Basic Information Ensembl ID: ENSMUSG00000028364 Description: tenascin C [Source:MGI Symbol;Acc:MGI:101922] Location: 4:63878022-63965252 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell fibroblast epithelial cell glial cell smooth muscle cell Other: Integrin cell surface interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Integrin signaling Pathway Hierarchies & Genes p130Cas linkage to MAPK signaling for integrins (6 genes) Signal Transduction Integrin signaling 3 genes GRB2:SOS provides linkage to MAPK signaling for Integrins p130Cas linkage to MAPK signaling for integrins 3 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Apbb1ip Gene Information Basic Information Ensembl ID: ENSMUSG00000026786 Description: amyloid beta precursor protein binding family B member 1 interacting protein [Source:MGI Symbol;Acc:MGI:1861354] Location: 2:22664106-22765665 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte monocyte granulocyte microglia Other: Integrin signaling MAPK family signaling cascades Platelet activation, signaling and aggregation Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Rap1a Gene Information Basic Information Ensembl ID: ENSMUSG00000068798 Description: RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852] Location: 3:105634583-105708652 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell monocyte muscle cell dendritic cell plasma cell megakaryocyte Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Rapgef4 Gene Information Basic Information Ensembl ID: ENSMUSG00000049044 Description: Rap guanine nucleotide exchange factor (GEF) 4 [Source:MGI Symbol;Acc:MGI:1917723] Location: 2:71811584-72087818 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell neuron adrenal cortical cell Other: Adaptive Immune System Integration of energy metabolism Integrin signaling Rasgrp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027347 Description: RAS guanyl releasing protein 1 [Source:MGI Symbol;Acc:MGI:1314635] Location: 2:117110474-117173482 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell Specialized T cell CD4+ T cell neuron Other: Adaptive Immune System Integrin signaling MAPK family signaling cascades
Intestinal absorption Pathway Hierarchies & Genes Intestinal hexose absorption (1 genes) Digestion and absorption Intestinal absorption Intestinal hexose absorption 1 genes	Slc2a2 Gene Information Basic Information Ensembl ID: ENSMUSG00000027690 Description: solute carrier family 2 (facilitated glucose transporter)%2C member 2 [Source:MGI Symbol;Acc:MGI:1095438] Location: 3:28752052-28785508 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Integration of energy metabolism SLC-mediated transmembrane transport Intestinal absorption
Intracellular oxygen transport Pathway Hierarchies & Genes Intracellular oxygen transport (1 genes) Transport of small molecules Intracellular oxygen transport 1 genes	Ngb Gene Information Basic Information Ensembl ID: ENSMUSG00000021032 Description: neuroglobin [Source:MGI Symbol;Acc:MGI:2151886] Location: 12:87144305-87149313 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular oxygen transport
Intracellular signaling by second messengers Pathway Hierarchies & Genes PKA activation (3 genes) Signal Transduction Intracellular signaling by second messengers DAG and IP3 signaling CaM pathway Calmodulin induced events PKA-mediated phosphorylation of CREB PKA activation 3 genes Cam-PDE 1 activation (2 genes) Signal Transduction Intracellular signaling by second messengers DAG and IP3 signaling CaM pathway Calmodulin induced events Cam-PDE 1 activation 2 genes Calmodulin induced events (2 genes) Signal Transduction Intracellular signaling by second messengers DAG and IP3 signaling CaM pathway Calmodulin induced events 2 genes PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (24 genes) Signal Transduction Intracellular signaling by second messengers PIP3 activates AKT signaling Negative regulation of the PI3K/AKT network PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling 24 genes Regulation of PTEN localization (1 genes) Signal Transduction Intracellular signaling by second messengers PIP3 activates AKT signaling PTEN Regulation Regulation of PTEN localization 1 genes AKT phosphorylates targets in the cytosol (1 genes) Signal Transduction Intracellular signaling by second messengers PIP3 activates AKT signaling AKT phosphorylates targets in the cytosol 1 genes AKT phosphorylates targets in the nucleus (1 genes) Signal Transduction Intracellular signaling by second messengers PIP3 activates AKT signaling AKT phosphorylates targets in the nucleus 1 genes Negative regulation of the PI3K/AKT network (1 genes) Signal Transduction Intracellular signaling by second messengers PIP3 activates AKT signaling Negative regulation of the PI3K/AKT network 1 genes DAG and IP3 signaling (1 genes) Signal Transduction Intracellular signaling by second messengers DAG and IP3 signaling 1 genes	Adcy1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020431 Description: adenylate cyclase 1 [Source:MGI Symbol;Acc:MGI:99677] Location: 11:7013489-7128506 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Transmission across Chemical Synapses Signaling by GPCR Signaling by Hedgehog Adcy2 Gene Information Basic Information Ensembl ID: ENSMUSG00000021536 Description: adenylate cyclase 2 [Source:MGI Symbol;Acc:MGI:99676] Location: 13:68768162-69147660 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell skeletal muscle cell excitatory neuron Other: Transmission across Chemical Synapses Signaling by GPCR Signaling by Hedgehog Adcy5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022840 Description: adenylate cyclase 5 [Source:MGI Symbol;Acc:MGI:99673] Location: 16:34975247-35126108 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell projection neuron Other: Transmission across Chemical Synapses Integration of energy metabolism Signaling by GPCR Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Bdnf Gene Information Basic Information Ensembl ID: ENSMUSG00000048482 Description: brain derived neurotrophic factor [Source:MGI Symbol;Acc:MGI:88145] Location: 2:109505045-109557352 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Cdkn1a Gene Information Basic Information Ensembl ID: ENSMUSG00000023067 Description: cyclin dependent kinase inhibitor 1A [Source:MGI Symbol;Acc:MGI:104556] Location: 17:29309950-29319701 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast muscle cell smooth muscle cell schwann cell monocyte epithelial cell Other: Cellular responses to stress Cell Cycle, Mitotic Cell Cycle Checkpoints Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Erbb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000062312 Description: erb-b2 receptor tyrosine kinase 2 [Source:MGI Symbol;Acc:MGI:95410] Location: 11:98303296-98328542 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Erbb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000018166 Description: erb-b2 receptor tyrosine kinase 3 [Source:MGI Symbol;Acc:MGI:95411] Location: 10:128403392-128425521 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell schwann cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Erbb4 Gene Information Basic Information Ensembl ID: ENSMUSG00000062209 Description: erb-b2 receptor tyrosine kinase 4 [Source:MGI Symbol;Acc:MGI:104771] Location: 1:68071345-69147218 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: inhibitory neuron Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Fgf10 Gene Information Basic Information Ensembl ID: ENSMUSG00000021732 Description: fibroblast growth factor 10 [Source:MGI Symbol;Acc:MGI:1099809] Location: 13:118806327-118928651 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cochleovestibular ganglion cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Fgfr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000054252 Description: fibroblast growth factor receptor 3 [Source:MGI Symbol;Acc:MGI:95524] Location: 5:33879018-33894412 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell astrocyte supporting cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Foxo1 Gene Information Basic Information Ensembl ID: ENSMUSG00000044167 Description: forkhead box O1 [Source:MGI Symbol;Acc:MGI:1890077] Location: 3:52175757-52260642 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell epithelial cell Other: Regulation of beta-cell development MAPK family signaling cascades RNA Polymerase II Transcription Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Hgf Gene Information Basic Information Ensembl ID: ENSMUSG00000028864 Description: hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079] Location: 5:16758493-16825150 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell stellate cell eosinophil Other: MAPK family signaling cascades Platelet activation, signaling and aggregation Intracellular signaling by second messengers Il1rap Gene Information Basic Information Ensembl ID: ENSMUSG00000022514 Description: interleukin 1 receptor accessory protein [Source:MGI Symbol;Acc:MGI:104975] Location: 16:26400454-26548867 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell bipolar cell neuron Other: Cytokine Signaling in Immune system Protein-protein interactions at synapses Intracellular signaling by second messengers Insr Gene Information Basic Information Ensembl ID: ENSMUSG00000005534 Description: insulin receptor [Source:MGI Symbol;Acc:MGI:96575] Location: 8:3172061-3329617 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell adrenal cortical cell adipocyte Other: Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Irs2 Gene Information Basic Information Ensembl ID: ENSMUSG00000038894 Description: insulin receptor substrate 2 [Source:MGI Symbol;Acc:MGI:109334] Location: 8:11034681-11058458 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mural cell Other: Cytokine Signaling in Immune system MAPK family signaling cascades Signaling by Erythropoietin Kit Gene Information Basic Information Ensembl ID: ENSMUSG00000005672 Description: KIT proto-oncogene receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:96677] Location: 5:75735576-75817382 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell natural killer cell interneuron epithelial cell intercalated cell tuft cell mast cell innate lymphoid cell hematopoietic stem cell progenitor cell dendritic cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Kitl Gene Information Basic Information Ensembl ID: ENSMUSG00000019966 Description: kit ligand [Source:MGI Symbol;Acc:MGI:96974] Location: 10:99851492-99936278 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stromal cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Kl Gene Information Basic Information Ensembl ID: ENSMUSG00000058488 Description: klotho [Source:MGI Symbol;Acc:MGI:1101771] Location: 5:150876072-150917282 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Met Gene Information Basic Information Ensembl ID: ENSMUSG00000009376 Description: met proto-oncogene [Source:MGI Symbol;Acc:MGI:96969] Location: 6:17463799-17573979 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell intercalated cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Ntrk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000059146 Description: neurotrophic tyrosine kinase%2C receptor%2C type 3 [Source:MGI Symbol;Acc:MGI:97385] Location: 7:77825707-78387760 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Protein-protein interactions at synapses Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Pde1a Gene Information Basic Information Ensembl ID: ENSMUSG00000059173 Description: phosphodiesterase 1A%2C calmodulin-dependent [Source:MGI Symbol;Acc:MGI:1201792] Location: 2:79664797-79959802 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell preadipocyte stellate cell smooth muscle cell neuron Other: Signaling by GPCR Platelet homeostasis Intracellular signaling by second messengers Pde1b Gene Information Basic Information Ensembl ID: ENSMUSG00000022489 Description: phosphodiesterase 1B%2C Ca2+-calmodulin dependent [Source:MGI Symbol;Acc:MGI:97523] Location: 15:103411461-103438479 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet homeostasis Intracellular signaling by second messengers Pdgfra Gene Information Basic Information Ensembl ID: ENSMUSG00000029231 Description: platelet derived growth factor receptor%2C alpha polypeptide [Source:MGI Symbol;Acc:MGI:97530] Location: 5:75312953-75358876 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell embryonic cell stromal cell astrocyte oligodendrocyte precursor cell oligodendrocyte mesenchymal cell telocyte extracellular matrix producing cell progenitor cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Pdgfrb Gene Information Basic Information Ensembl ID: ENSMUSG00000024620 Description: platelet derived growth factor receptor%2C beta polypeptide [Source:MGI Symbol;Acc:MGI:97531] Location: 18:61178222-61218133 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stellate cell mural cell mesenchymal cell mesangial cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Phlpp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000044340 Description: PH domain and leucine rich repeat protein phosphatase 1 [Source:MGI Symbol;Acc:MGI:2138327] Location: 1:106099482-106321980 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell glial cell astrocyte Other: Intracellular signaling by second messengers Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system Prkce Gene Information Basic Information Ensembl ID: ENSMUSG00000045038 Description: protein kinase C%2C epsilon [Source:MGI Symbol;Acc:MGI:97599] Location: 17:86475213-86965347 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by GPCR Platelet activation, signaling and aggregation Prkcg Gene Information Basic Information Ensembl ID: ENSMUSG00000078816 Description: protein kinase C%2C gamma [Source:MGI Symbol;Acc:MGI:97597] Location: 7:3337704-3379615 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Signaling by WNT Signaling by GPCR Pten Gene Information Basic Information Ensembl ID: ENSMUSG00000013663 Description: phosphatase and tensin homolog [Source:MGI Symbol;Acc:MGI:109583] Location: 19:32734897-32803560 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Inositol phosphate metabolism Metabolism of lipids Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System
Ion channel transport Pathway Hierarchies & Genes TRP channels (13 genes) Transport of small molecules Ion channel transport 2 genes Stimuli-sensing channels 10 genes TRP channels 1 genes	Ano3 Gene Information Basic Information Ensembl ID: ENSMUSG00000074968 Description: anoctamin 3 [Source:MGI Symbol;Acc:MGI:3613666] Location: 2:110485546-110781268 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bipolar cell excitatory neuron Other: Ion channel transport Atp2b4 Gene Information Basic Information Ensembl ID: ENSMUSG00000026463 Description: ATPase%2C Ca++ transporting%2C plasma membrane 4 [Source:MGI Symbol;Acc:MGI:88111] Location: 1:133627195-133728779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell hematopoietic progenitor cell Other: Platelet homeostasis Cardiac conduction Ion channel transport Atp6v0a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019302 Description: ATPase%2C H+ transporting%2C lysosomal V0 subunit A1 [Source:MGI Symbol;Acc:MGI:103286] Location: 11:100900278-100954545 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte eosinophil Other: Innate Immune System Signaling by Receptor Tyrosine Kinases Iron uptake and transport Atp6v1a Gene Information Basic Information Ensembl ID: ENSMUSG00000052459 Description: ATPase%2C H+ transporting%2C lysosomal V1 subunit A [Source:MGI Symbol;Acc:MGI:1201780] Location: 16:43905765-43960068 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Cellular responses to stress Signaling by Receptor Tyrosine Kinases Camk2a Gene Information Basic Information Ensembl ID: ENSMUSG00000024617 Description: calcium/calmodulin-dependent protein kinase II alpha [Source:MGI Symbol;Acc:MGI:88256] Location: 18:61058690-61121224 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Signaling by WNT Camk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000057897 Description: calcium/calmodulin-dependent protein kinase II%2C beta [Source:MGI Symbol;Acc:MGI:88257] Location: 11:5919644-6016362 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: kidney cell neuron enteroendocrine cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2d Gene Information Basic Information Ensembl ID: ENSMUSG00000053819 Description: calcium/calmodulin-dependent protein kinase II%2C delta [Source:MGI Symbol;Acc:MGI:1341265] Location: 3:126389951-126639975 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2g Gene Information Basic Information Ensembl ID: ENSMUSG00000021820 Description: calcium/calmodulin-dependent protein kinase II gamma [Source:MGI Symbol;Acc:MGI:88259] Location: 14:20784943-20844156 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Fxyd6 Gene Information Basic Information Ensembl ID: ENSMUSG00000066705 Description: FXYD domain-containing ion transport regulator 6 [Source:MGI Symbol;Acc:MGI:1890226] Location: 9:45281483-45307457 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell interneuron glial cell enteroendocrine cell dendritic cell Other: Cardiac conduction Ion channel transport Nedd4l Gene Information Basic Information Ensembl ID: ENSMUSG00000024589 Description: neural precursor cell expressed%2C developmentally down-regulated gene 4-like [Source:MGI Symbol;Acc:MGI:1933754] Location: 18:65020776-65350899 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Adaptive Immune System RNA Polymerase II Transcription Signaling by TGFB family members Ryr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000021313 Description: ryanodine receptor 2%2C cardiac [Source:MGI Symbol;Acc:MGI:99685] Location: 13:11567988-12121831 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron endocrine cell cardiomyocyte smooth muscle cell theca cell Other: Ion channel transport Cardiac conduction Ryr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000057378 Description: ryanodine receptor 3 [Source:MGI Symbol;Acc:MGI:99684] Location: 2:112461700-113047441 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron skeletal muscle cell Other: Cardiac conduction Ion channel transport Trpc7 Gene Information Basic Information Ensembl ID: ENSMUSG00000021541 Description: transient receptor potential cation channel%2C subfamily C%2C member 7 [Source:MGI Symbol;Acc:MGI:1349470] Location: 13:56920926-57043806 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet homeostasis Platelet activation, signaling and aggregation
Iron uptake and transport Pathway Hierarchies & Genes Transferrin endocytosis and recycling (2 genes) Transport of small molecules Iron uptake and transport Transferrin endocytosis and recycling 2 genes	Atp6v0a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019302 Description: ATPase%2C H+ transporting%2C lysosomal V0 subunit A1 [Source:MGI Symbol;Acc:MGI:103286] Location: 11:100900278-100954545 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte eosinophil Other: Innate Immune System Signaling by Receptor Tyrosine Kinases Iron uptake and transport Atp6v1a Gene Information Basic Information Ensembl ID: ENSMUSG00000052459 Description: ATPase%2C H+ transporting%2C lysosomal V1 subunit A [Source:MGI Symbol;Acc:MGI:1201780] Location: 16:43905765-43960068 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Cellular responses to stress Signaling by Receptor Tyrosine Kinases
Keratinization Pathway Hierarchies & Genes Formation of the cornified envelope (1 genes) Developmental Biology Keratinization Formation of the cornified envelope 1 genes	Dsg2 Gene Information Basic Information Ensembl ID: ENSMUSG00000044393 Description: desmoglein 2 [Source:MGI Symbol;Acc:MGI:1196466] Location: 18:20691131-20737578 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell tuft cell epithelial cell Other: Apoptosis Keratinization Signaling by Rho GTPases, Miro GTPases and RHOBTB3
LGI-ADAM interactions Pathway Hierarchies & Genes LGI-ADAM interactions (5 genes) Developmental Biology LGI-ADAM interactions 5 genes	Adam22 Gene Information Basic Information Ensembl ID: ENSMUSG00000040537 Description: a disintegrin and metallopeptidase domain 22 [Source:MGI Symbol;Acc:MGI:1340046] Location: 5:8122352-8418160 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: LGI-ADAM interactions Cacng3 Gene Information Basic Information Ensembl ID: ENSMUSG00000066189 Description: calcium channel%2C voltage-dependent%2C gamma subunit 3 [Source:MGI Symbol;Acc:MGI:1859165] Location: 7:122269715-122368616 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron retina cell Other: Transmission across Chemical Synapses LGI-ADAM interactions Dlg4 Gene Information Basic Information Ensembl ID: ENSMUSG00000020886 Description: discs large MAGUK scaffold protein 4 [Source:MGI Symbol;Acc:MGI:1277959] Location: 11:69907768-69938348 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Transmission across Chemical Synapses LGI-ADAM interactions MAPK family signaling cascades Lgi2 Gene Information Basic Information Ensembl ID: ENSMUSG00000039252 Description: leucine-rich repeat LGI family%2C member 2 [Source:MGI Symbol;Acc:MGI:2180196] Location: 5:52690859-52723804 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell interneuron Other: LGI-ADAM interactions Stx1a Gene Information Basic Information Ensembl ID: ENSMUSG00000007207 Description: syntaxin 1A (brain) [Source:MGI Symbol;Acc:MGI:109355] Location: 5:135052336-135079954 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system LGI-ADAM interactions
MAPK family signaling cascades Pathway Hierarchies & Genes Negative feedback regulation of MAPK pathway (2 genes) Signal Transduction MAPK family signaling cascades MAPK1/MAPK3 signaling RAF/MAP kinase cascade Negative regulation of MAPK pathway Negative feedback regulation of MAPK pathway 2 genes MAP2K and MAPK activation (3 genes) Signal Transduction MAPK family signaling cascades MAPK1/MAPK3 signaling RAF/MAP kinase cascade MAP2K and MAPK activation 3 genes MAPK3 (ERK1) activation (1 genes) Signal Transduction MAPK family signaling cascades MAPK1/MAPK3 signaling RAF-independent MAPK1/3 activation MAPK3 (ERK1) activation 1 genes RAF activation (4 genes) Signal Transduction MAPK family signaling cascades MAPK1/MAPK3 signaling RAF/MAP kinase cascade RAF activation 4 genes RAS processing (2 genes) Signal Transduction MAPK family signaling cascades MAPK1/MAPK3 signaling RAF/MAP kinase cascade RAS processing 2 genes Regulation of RAS by GAPs (3 genes) Signal Transduction MAPK family signaling cascades MAPK1/MAPK3 signaling RAF/MAP kinase cascade Regulation of RAS by GAPs 3 genes RAF/MAP kinase cascade (24 genes) Signal Transduction MAPK family signaling cascades MAPK1/MAPK3 signaling RAF/MAP kinase cascade 24 genes MAPK6/MAPK4 signaling (1 genes) Signal Transduction MAPK family signaling cascades MAPK6/MAPK4 signaling 1 genes	Angpt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000022309 Description: angiopoietin 1 [Source:MGI Symbol;Acc:MGI:108448] Location: 15:42288119-42540373 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast preadipocyte cardiomyocyte astrocyte Other: Cell surface interactions at the vascular wall MAPK family signaling cascades Apbb1ip Gene Information Basic Information Ensembl ID: ENSMUSG00000026786 Description: amyloid beta precursor protein binding family B member 1 interacting protein [Source:MGI Symbol;Acc:MGI:1861354] Location: 2:22664106-22765665 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte monocyte granulocyte microglia Other: Integrin signaling MAPK family signaling cascades Platelet activation, signaling and aggregation Bcl2l1 Gene Information Basic Information Ensembl ID: ENSMUSG00000007659 Description: BCL2-like 1 [Source:MGI Symbol;Acc:MGI:88139] Location: 2:152622588-152673648 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Innate Immune System MAPK family signaling cascades Camk2a Gene Information Basic Information Ensembl ID: ENSMUSG00000024617 Description: calcium/calmodulin-dependent protein kinase II alpha [Source:MGI Symbol;Acc:MGI:88256] Location: 18:61058690-61121224 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Signaling by WNT Camk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000057897 Description: calcium/calmodulin-dependent protein kinase II%2C beta [Source:MGI Symbol;Acc:MGI:88257] Location: 11:5919644-6016362 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: kidney cell neuron enteroendocrine cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2d Gene Information Basic Information Ensembl ID: ENSMUSG00000053819 Description: calcium/calmodulin-dependent protein kinase II%2C delta [Source:MGI Symbol;Acc:MGI:1341265] Location: 3:126389951-126639975 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2g Gene Information Basic Information Ensembl ID: ENSMUSG00000021820 Description: calcium/calmodulin-dependent protein kinase II gamma [Source:MGI Symbol;Acc:MGI:88259] Location: 14:20784943-20844156 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Dlg4 Gene Information Basic Information Ensembl ID: ENSMUSG00000020886 Description: discs large MAGUK scaffold protein 4 [Source:MGI Symbol;Acc:MGI:1277959] Location: 11:69907768-69938348 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Transmission across Chemical Synapses LGI-ADAM interactions MAPK family signaling cascades Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Erbb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000062312 Description: erb-b2 receptor tyrosine kinase 2 [Source:MGI Symbol;Acc:MGI:95410] Location: 11:98303296-98328542 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Erbb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000018166 Description: erb-b2 receptor tyrosine kinase 3 [Source:MGI Symbol;Acc:MGI:95411] Location: 10:128403392-128425521 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell schwann cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Erbb4 Gene Information Basic Information Ensembl ID: ENSMUSG00000062209 Description: erb-b2 receptor tyrosine kinase 4 [Source:MGI Symbol;Acc:MGI:104771] Location: 1:68071345-69147218 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: inhibitory neuron Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Fgf10 Gene Information Basic Information Ensembl ID: ENSMUSG00000021732 Description: fibroblast growth factor 10 [Source:MGI Symbol;Acc:MGI:1099809] Location: 13:118806327-118928651 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cochleovestibular ganglion cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Fgfr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000054252 Description: fibroblast growth factor receptor 3 [Source:MGI Symbol;Acc:MGI:95524] Location: 5:33879018-33894412 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell astrocyte supporting cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Foxo1 Gene Information Basic Information Ensembl ID: ENSMUSG00000044167 Description: forkhead box O1 [Source:MGI Symbol;Acc:MGI:1890077] Location: 3:52175757-52260642 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell epithelial cell Other: Regulation of beta-cell development MAPK family signaling cascades RNA Polymerase II Transcription Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Gdnf Gene Information Basic Information Ensembl ID: ENSMUSG00000022144 Description: glial cell line derived neurotrophic factor [Source:MGI Symbol;Acc:MGI:107430] Location: 15:7840327-7867056 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades Nervous system development Gfra1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025089 Description: glial cell line derived neurotrophic factor family receptor alpha 1 [Source:MGI Symbol;Acc:MGI:1100842] Location: 19:58224036-58444341 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell stem cell Other: MAPK family signaling cascades Nervous system development Grin1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026959 Description: glutamate receptor%2C ionotropic%2C NMDA1 (zeta 1) [Source:MGI Symbol;Acc:MGI:95819] Location: 2:25181193-25209199 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses MAPK family signaling cascades Protein-protein interactions at synapses Hgf Gene Information Basic Information Ensembl ID: ENSMUSG00000028864 Description: hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079] Location: 5:16758493-16825150 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell stellate cell eosinophil Other: MAPK family signaling cascades Platelet activation, signaling and aggregation Intracellular signaling by second messengers Irs2 Gene Information Basic Information Ensembl ID: ENSMUSG00000038894 Description: insulin receptor substrate 2 [Source:MGI Symbol;Acc:MGI:109334] Location: 8:11034681-11058458 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mural cell Other: Cytokine Signaling in Immune system MAPK family signaling cascades Signaling by Erythropoietin Kit Gene Information Basic Information Ensembl ID: ENSMUSG00000005672 Description: KIT proto-oncogene receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:96677] Location: 5:75735576-75817382 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell natural killer cell interneuron epithelial cell intercalated cell tuft cell mast cell innate lymphoid cell hematopoietic stem cell progenitor cell dendritic cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Kitl Gene Information Basic Information Ensembl ID: ENSMUSG00000019966 Description: kit ligand [Source:MGI Symbol;Acc:MGI:96974] Location: 10:99851492-99936278 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stromal cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Kl Gene Information Basic Information Ensembl ID: ENSMUSG00000058488 Description: klotho [Source:MGI Symbol;Acc:MGI:1101771] Location: 5:150876072-150917282 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Met Gene Information Basic Information Ensembl ID: ENSMUSG00000009376 Description: met proto-oncogene [Source:MGI Symbol;Acc:MGI:96969] Location: 6:17463799-17573979 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell intercalated cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Pdgfra Gene Information Basic Information Ensembl ID: ENSMUSG00000029231 Description: platelet derived growth factor receptor%2C alpha polypeptide [Source:MGI Symbol;Acc:MGI:97530] Location: 5:75312953-75358876 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell embryonic cell stromal cell astrocyte oligodendrocyte precursor cell oligodendrocyte mesenchymal cell telocyte extracellular matrix producing cell progenitor cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Pdgfrb Gene Information Basic Information Ensembl ID: ENSMUSG00000024620 Description: platelet derived growth factor receptor%2C beta polypeptide [Source:MGI Symbol;Acc:MGI:97531] Location: 18:61178222-61218133 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stellate cell mural cell mesenchymal cell mesangial cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Prkcq Gene Information Basic Information Ensembl ID: ENSMUSG00000026778 Description: protein kinase C%2C theta [Source:MGI Symbol;Acc:MGI:97601] Location: 2:11176919-11306033 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell CD8+ T cell Specialized T cell Other: Apoptosis Adaptive Immune System Innate Immune System Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Rap1a Gene Information Basic Information Ensembl ID: ENSMUSG00000068798 Description: RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852] Location: 3:105634583-105708652 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell monocyte muscle cell dendritic cell plasma cell megakaryocyte Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Rapgef2 Gene Information Basic Information Ensembl ID: ENSMUSG00000062232 Description: Rap guanine nucleotide exchange factor (GEF) 2 [Source:MGI Symbol;Acc:MGI:2659071] Location: 3:78969823-79193824 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte endothelial cell mast cell Other: MAPK family signaling cascades Rasal1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029602 Description: RAS protein activator like 1 (GAP1 like) [Source:MGI Symbol;Acc:MGI:1330842] Location: 5:120786877-120817662 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades Rasal2 Gene Information Basic Information Ensembl ID: ENSMUSG00000070565 Description: RAS protein activator like 2 [Source:MGI Symbol;Acc:MGI:2443881] Location: 1:156962752-157240165 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell glial cell smooth muscle cell neuron Other: MAPK family signaling cascades Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Rasgrp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027347 Description: RAS guanyl releasing protein 1 [Source:MGI Symbol;Acc:MGI:1314635] Location: 2:117110474-117173482 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell Specialized T cell CD4+ T cell neuron Other: Adaptive Immune System Integrin signaling MAPK family signaling cascades Ret Gene Information Basic Information Ensembl ID: ENSMUSG00000030110 Description: ret proto-oncogene [Source:MGI Symbol;Acc:MGI:97902] Location: 6:118128706-118174679 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron autonomic neuron Other: MAPK family signaling cascades Nervous system development Syngap1 Gene Information Basic Information Ensembl ID: ENSMUSG00000067629 Description: synaptic Ras GTPase activating protein 1 homolog (rat) [Source:MGI Symbol;Acc:MGI:3039785] Location: 17:27160227-27191408 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades
MITF-M-regulated melanocyte development Pathway Hierarchies & Genes Regulation of MITF-M-dependent genes involved in cell cycle and proliferation (3 genes) Developmental Biology MITF-M-regulated melanocyte development MITF-M-dependent gene expression Regulation of MITF-M-dependent genes involved in cell cycle and proliferation 3 genes Regulation of MITF-M-dependent genes involved in pigmentation (1 genes) Developmental Biology MITF-M-regulated melanocyte development MITF-M-dependent gene expression Regulation of MITF-M-dependent genes involved in pigmentation 1 genes Transcriptional and post-translational regulation of MITF-M expression and activity (8 genes) Developmental Biology MITF-M-regulated melanocyte development Transcriptional and post-translational regulation of MITF-M expression and activity 8 genes	Csf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000014599 Description: colony stimulating factor 1 (macrophage) [Source:MGI Symbol;Acc:MGI:1339753] Location: 3:107648364-107667785 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell basophil eosinophil Other: Cytokine Signaling in Immune system Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Kit Gene Information Basic Information Ensembl ID: ENSMUSG00000005672 Description: KIT proto-oncogene receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:96677] Location: 5:75735576-75817382 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell natural killer cell interneuron epithelial cell intercalated cell tuft cell mast cell innate lymphoid cell hematopoietic stem cell progenitor cell dendritic cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Kitl Gene Information Basic Information Ensembl ID: ENSMUSG00000019966 Description: kit ligand [Source:MGI Symbol;Acc:MGI:96974] Location: 10:99851492-99936278 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stromal cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Lef1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027985 Description: lymphoid enhancer binding factor 1 [Source:MGI Symbol;Acc:MGI:96770] Location: 3:130904120-131018005 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell developing T cell lymphoid progenitor cell Specialized T cell melanocyte CD8+ T cell memory T cell Other: Signaling by WNT RNA Polymerase II Transcription MITF-M-regulated melanocyte development Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Rps6ka1 Gene Information Basic Information Ensembl ID: ENSMUSG00000003644 Description: ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:104558] Location: 4:133574601-133615108 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Innate Immune System Sox10 Gene Information Basic Information Ensembl ID: ENSMUSG00000033006 Description: SRY (sex determining region Y)-box 10 [Source:MGI Symbol;Acc:MGI:98358] Location: 15:79039108-79049440 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neural crest cell oligodendrocyte oligodendrocyte precursor cell glial cell schwann cell autonomic neuron progenitor cell Other: MITF-M-regulated melanocyte development Tbx3 Gene Information Basic Information Ensembl ID: ENSMUSG00000018604 Description: T-box 3 [Source:MGI Symbol;Acc:MGI:98495] Location: 5:119808734-119822789 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stellate cell epithelial cell Other: MITF-M-regulated melanocyte development Tcf7l2 Gene Information Basic Information Ensembl ID: ENSMUSG00000024985 Description: transcription factor 7 like 2%2C T cell specific%2C HMG box [Source:MGI Symbol;Acc:MGI:1202879] Location: 19:55730252-55922086 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell fibroblast macrophage excitatory neuron mesenchymal cell oligodendrocyte Other: Signaling by WNT RNA Polymerase II Transcription MITF-M-regulated melanocyte development
MTOR signalling Pathway Hierarchies & Genes Energy dependent regulation of mTOR by LKB1-AMPK (2 genes) Signal Transduction MTOR signalling 1 genes Energy dependent regulation of mTOR by LKB1-AMPK 1 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Prkaa2 Gene Information Basic Information Ensembl ID: ENSMUSG00000028518 Description: protein kinase%2C AMP-activated%2C alpha 2 catalytic subunit [Source:MGI Symbol;Acc:MGI:1336173] Location: 4:104887071-104967087 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Macroautophagy Integration of energy metabolism MTOR signalling
Macroautophagy Pathway Hierarchies & Genes PINK1-PRKN Mediated Mitophagy (6 genes) Autophagy Macroautophagy 1 genes Selective autophagy Mitophagy 2 genes PINK1-PRKN Mediated Mitophagy 3 genes	Cftr Gene Information Basic Information Ensembl ID: ENSMUSG00000041301 Description: cystic fibrosis transmembrane conductance regulator [Source:MGI Symbol;Acc:MGI:88388] Location: 6:18170686-18322767 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pneumocyte ionocyte Other: Macroautophagy Membrane Trafficking ABC-family proteins mediated transport Dync1li2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035770 Description: dynein%2C cytoplasmic 1 light intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107738] Location: 8:105144312-105169679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Membrane Trafficking Optn Gene Information Basic Information Ensembl ID: ENSMUSG00000026672 Description: optineurin [Source:MGI Symbol;Acc:MGI:1918898] Location: 2:5025453-5068862 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Macroautophagy Innate Immune System Membrane Trafficking Pink1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028756 Description: PTEN induced putative kinase 1 [Source:MGI Symbol;Acc:MGI:1916193] Location: 4:138040720-138053618 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Macroautophagy Prkaa2 Gene Information Basic Information Ensembl ID: ENSMUSG00000028518 Description: protein kinase%2C AMP-activated%2C alpha 2 catalytic subunit [Source:MGI Symbol;Acc:MGI:1336173] Location: 4:104887071-104967087 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Macroautophagy Integration of energy metabolism MTOR signalling Prkn Gene Information Basic Information Ensembl ID: ENSMUSG00000023826 Description: parkin RBR E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1355296] Location: 17:11059271-12282248 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Regulated Necrosis
Membrane Trafficking Pathway Hierarchies & Genes COPI-independent Golgi-to-ER retrograde traffic (1 genes) Vesicle-mediated transport Membrane Trafficking ER to Golgi Anterograde Transport COPI-mediated anterograde transport Intra-Golgi and retrograde Golgi-to-ER traffic Golgi-to-ER retrograde transport COPI-independent Golgi-to-ER retrograde traffic 1 genes Clathrin-mediated endocytosis (1 genes) Vesicle-mediated transport Membrane Trafficking Gap junction trafficking and regulation Gap junction trafficking Gap junction degradation Formation of annular gap junctions Clathrin-mediated endocytosis 1 genes Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane (1 genes) Vesicle-mediated transport Membrane Trafficking Gap junction trafficking and regulation Gap junction trafficking Gap junction assembly Transport of connexons to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane 1 genes Oligomerization of connexins into connexons (1 genes) Vesicle-mediated transport Membrane Trafficking Gap junction trafficking and regulation Gap junction trafficking Gap junction assembly Oligomerization of connexins into connexons 1 genes COPI-dependent Golgi-to-ER retrograde traffic (3 genes) Vesicle-mediated transport Membrane Trafficking Intra-Golgi and retrograde Golgi-to-ER traffic Golgi-to-ER retrograde transport COPI-dependent Golgi-to-ER retrograde traffic 3 genes Gap junction assembly (1 genes) Vesicle-mediated transport Membrane Trafficking Gap junction trafficking and regulation Gap junction trafficking Gap junction assembly 1 genes Gap junction degradation (1 genes) Vesicle-mediated transport Membrane Trafficking Gap junction trafficking and regulation Gap junction trafficking Gap junction degradation 1 genes COPII-mediated vesicle transport (1 genes) Vesicle-mediated transport Membrane Trafficking ER to Golgi Anterograde Transport COPII-mediated vesicle transport 1 genes Cargo recognition for clathrin-mediated endocytosis (10 genes) Vesicle-mediated transport Membrane Trafficking Clathrin-mediated endocytosis Cargo recognition for clathrin-mediated endocytosis 10 genes RAB GEFs exchange GTP for GDP on RABs (2 genes) Vesicle-mediated transport Membrane Trafficking Rab regulation of trafficking RAB GEFs exchange GTP for GDP on RABs 2 genes TBC/RABGAPs (1 genes) Vesicle-mediated transport Membrane Trafficking Rab regulation of trafficking TBC/RABGAPs 1 genes	Adrb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000045730 Description: adrenergic receptor%2C beta 2 [Source:MGI Symbol;Acc:MGI:87938] Location: 18:62310887-62313030 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell erythroblast Other: Membrane Trafficking Signaling by GPCR Post-translational protein modification Agtr1a Gene Information Basic Information Ensembl ID: ENSMUSG00000049115 Description: angiotensin II receptor%2C type 1a [Source:MGI Symbol;Acc:MGI:87964] Location: 13:30520424-30566850 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell pericyte stellate cell fibroblast adrenal cortical cell Other: Membrane Trafficking Signaling by GPCR Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Avpr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031390 Description: arginine vasopressin receptor 2 [Source:MGI Symbol;Acc:MGI:88123] Location: X:72935708-72939108 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Membrane Trafficking Signaling by GPCR Aquaporin-mediated transport Cenpe Gene Information Basic Information Ensembl ID: ENSMUSG00000045328 Description: centromere protein E [Source:MGI Symbol;Acc:MGI:1098230] Location: 3:134918298-134979372 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Cell Cycle, Mitotic Cftr Gene Information Basic Information Ensembl ID: ENSMUSG00000041301 Description: cystic fibrosis transmembrane conductance regulator [Source:MGI Symbol;Acc:MGI:88388] Location: 6:18170686-18322767 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pneumocyte ionocyte Other: Macroautophagy Membrane Trafficking ABC-family proteins mediated transport Chrm2 Gene Information Basic Information Ensembl ID: ENSMUSG00000045613 Description: cholinergic receptor%2C muscarinic 2%2C cardiac [Source:MGI Symbol;Acc:MGI:88397] Location: 6:36365019-36505349 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte excitatory neuron Other: Membrane Trafficking Signaling by GPCR Dnm1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026825 Description: dynamin 1 [Source:MGI Symbol;Acc:MGI:107384] Location: 2:32198483-32243350 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Innate Immune System Membrane Trafficking Dync1li2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035770 Description: dynein%2C cytoplasmic 1 light intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107738] Location: 8:105144312-105169679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Membrane Trafficking Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Epn2 Gene Information Basic Information Ensembl ID: ENSMUSG00000001036 Description: epsin 2 [Source:MGI Symbol;Acc:MGI:1333766] Location: 11:61408075-61470513 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell oligodendrocyte precursor cell Other: Membrane Trafficking Gja1 Gene Information Basic Information Ensembl ID: ENSMUSG00000050953 Description: gap junction protein%2C alpha 1 [Source:MGI Symbol;Acc:MGI:95713] Location: 10:56253426-56278609 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: astrocyte Other: Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Gja5 Gene Information Basic Information Ensembl ID: ENSMUSG00000057123 Description: gap junction protein%2C alpha 5 [Source:MGI Symbol;Acc:MGI:95716] Location: 3:96812009-96984732 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell smooth muscle cell Other: Membrane Trafficking Gjb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000047797 Description: gap junction protein%2C beta 1 [Source:MGI Symbol;Acc:MGI:95719] Location: X:100419984-100429235 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Membrane Trafficking Gria1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020524 Description: glutamate receptor%2C ionotropic%2C AMPA1 (alpha 1) [Source:MGI Symbol;Acc:MGI:95808] Location: 11:56902213-57221070 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell neuron Other: Transmission across Chemical Synapses Membrane Trafficking Post-translational protein modification Grk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000042249 Description: G protein-coupled receptor kinase 3 [Source:MGI Symbol;Acc:MGI:87941] Location: 5:113058348-113163657 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bone cell monocyte dendritic cell Other: Membrane Trafficking Signaling by GPCR Kif11 Gene Information Basic Information Ensembl ID: ENSMUSG00000012443 Description: kinesin family member 11 [Source:MGI Symbol;Acc:MGI:1098231] Location: 19:37364851-37410307 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: hematopoietic cell Other: Adaptive Immune System Membrane Trafficking Factors involved in megakaryocyte development and platelet production Kif5a Gene Information Basic Information Ensembl ID: ENSMUSG00000074657 Description: kinesin family member 5A [Source:MGI Symbol;Acc:MGI:109564] Location: 10:127061565-127099217 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Myo6 Gene Information Basic Information Ensembl ID: ENSMUSG00000033577 Description: myosin VI [Source:MGI Symbol;Acc:MGI:104785] Location: 9:80072313-80219011 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell enteroendocrine cell glial cell astrocyte hair cell Other: Transmission across Chemical Synapses Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Optn Gene Information Basic Information Ensembl ID: ENSMUSG00000026672 Description: optineurin [Source:MGI Symbol;Acc:MGI:1918898] Location: 2:5025453-5068862 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Macroautophagy Innate Immune System Membrane Trafficking Rab3a Gene Information Basic Information Ensembl ID: ENSMUSG00000031840 Description: RAB3A%2C member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97843] Location: 8:71207328-71211323 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Innate Immune System Membrane Trafficking Syt2 Gene Information Basic Information Ensembl ID: ENSMUSG00000026452 Description: synaptotagmin II [Source:MGI Symbol;Acc:MGI:99666] Location: 1:134574415-134690331 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: retina cell neuron Other: Membrane Trafficking Tacr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000030043 Description: tachykinin receptor 1 [Source:MGI Symbol;Acc:MGI:98475] Location: 6:82379315-82537085 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Membrane Trafficking Signaling by GPCR
Metabolism of amino acids and derivatives Pathway Hierarchies & Genes Regulation of thyroid hormone activity (1 genes) Metabolism Metabolism of amino acids and derivatives Metabolism of amine-derived hormones Thyroxine biosynthesis Regulation of thyroid hormone activity 1 genes Sulfide oxidation to sulfate (1 genes) Metabolism Metabolism of amino acids and derivatives Sulfur amino acid metabolism Degradation of cysteine and homocysteine Sulfide oxidation to sulfate 1 genes Catecholamine biosynthesis (3 genes) Metabolism Metabolism of amino acids and derivatives Metabolism of amine-derived hormones Catecholamine biosynthesis 3 genes Serotonin and melatonin biosynthesis (1 genes) Metabolism Metabolism of amino acids and derivatives Metabolism of amine-derived hormones Serotonin and melatonin biosynthesis 1 genes Aspartate and asparagine metabolism (2 genes) Metabolism Metabolism of amino acids and derivatives Aspartate and asparagine metabolism 2 genes Choline catabolism (1 genes) Metabolism Metabolism of amino acids and derivatives Choline catabolism 1 genes Creatine metabolism (1 genes) Metabolism Metabolism of amino acids and derivatives Creatine metabolism 1 genes Glutamate and glutamine metabolism (2 genes) Metabolism Metabolism of amino acids and derivatives Glutamate and glutamine metabolism 2 genes Histidine catabolism (1 genes) Metabolism Metabolism of amino acids and derivatives Histidine catabolism 1 genes Lysine catabolism (1 genes) Metabolism Metabolism of amino acids and derivatives Lysine catabolism 1 genes Serine metabolism (1 genes) Metabolism Metabolism of amino acids and derivatives Serine metabolism 1 genes	Aspa Gene Information Basic Information Ensembl ID: ENSMUSG00000020774 Description: aspartoacylase [Source:MGI Symbol;Acc:MGI:87914] Location: 11:73195818-73220422 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron glial cell schwann cell Other: Metabolism of amino acids and derivatives Crym Gene Information Basic Information Ensembl ID: ENSMUSG00000030905 Description: crystallin%2C mu [Source:MGI Symbol;Acc:MGI:102675] Location: 7:119785603-119801334 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Metabolism of amino acids and derivatives Dbh Gene Information Basic Information Ensembl ID: ENSMUSG00000000889 Description: dopamine beta hydroxylase [Source:MGI Symbol;Acc:MGI:94864] Location: 2:27055245-27073212 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron autonomic neuron Other: Metabolism of amino acids and derivatives Ddc Gene Information Basic Information Ensembl ID: ENSMUSG00000020182 Description: dopa decarboxylase [Source:MGI Symbol;Acc:MGI:94876] Location: 11:11764101-11848144 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell enteroendocrine cell Other: Metabolism of amino acids and derivatives Dio3 Gene Information Basic Information Ensembl ID: ENSMUSG00000075707 Description: deiodinase%2C iodothyronine type III [Source:MGI Symbol;Acc:MGI:1306782] Location: 12:110245502-110247531 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of amino acids and derivatives Ethe1 Gene Information Basic Information Ensembl ID: ENSMUSG00000064254 Description: ethylmalonic encephalopathy 1 [Source:MGI Symbol;Acc:MGI:1913321] Location: 7:24286968-24308350 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of amino acids and derivatives Gls Gene Information Basic Information Ensembl ID: ENSMUSG00000026103 Description: glutaminase [Source:MGI Symbol;Acc:MGI:95752] Location: 1:52202607-52272391 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Metabolism of amino acids and derivatives RNA Polymerase II Transcription Gls2 Gene Information Basic Information Ensembl ID: ENSMUSG00000044005 Description: glutaminase 2 (liver%2C mitochondrial) [Source:MGI Symbol;Acc:MGI:2143539] Location: 10:128030326-128045873 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Metabolism of amino acids and derivatives RNA Polymerase II Transcription Hdc Gene Information Basic Information Ensembl ID: ENSMUSG00000027360 Description: histidine decarboxylase [Source:MGI Symbol;Acc:MGI:96062] Location: 2:126435587-126461219 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell natural killer cell epithelial cell mast cell granulocyte eosinophil myeloid cell modulatory neuron Other: Metabolism of amino acids and derivatives Serinc5 Gene Information Basic Information Ensembl ID: ENSMUSG00000021703 Description: serine incorporator 5 [Source:MGI Symbol;Acc:MGI:2444223] Location: 13:92747599-92848455 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell Other: Metabolism of amino acids and derivatives Slc25a12 Gene Information Basic Information Ensembl ID: ENSMUSG00000027010 Description: solute carrier family 25 (mitochondrial carrier%2C Aralar)%2C member 12 [Source:MGI Symbol;Acc:MGI:1926080] Location: 2:71101407-71198093 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Aerobic respiration and respiratory electron transport Metabolism of amino acids and derivatives Slc44a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028412 Description: solute carrier family 44%2C member 1 [Source:MGI Symbol;Acc:MGI:2140592] Location: 4:53440413-53622478 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: SLC-mediated transmembrane transport Metabolism of lipids Metabolism of amino acids and derivatives Slc6a11 Gene Information Basic Information Ensembl ID: ENSMUSG00000030307 Description: solute carrier family 6 (neurotransmitter transporter%2C GABA)%2C member 11 [Source:MGI Symbol;Acc:MGI:95630] Location: 6:114108202-114226913 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell astrocyte Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Metabolism of amino acids and derivatives Th Gene Information Basic Information Ensembl ID: ENSMUSG00000000214 Description: tyrosine hydroxylase [Source:MGI Symbol;Acc:MGI:98735] Location: 7:142446489-142484865 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: chemoreceptor cell Other: Metabolism of amino acids and derivatives Tph2 Gene Information Basic Information Ensembl ID: ENSMUSG00000006764 Description: tryptophan hydroxylase 2 [Source:MGI Symbol;Acc:MGI:2651811] Location: 10:114914546-115020927 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: rostromedial tegmental nucleu Other: Metabolism of amino acids and derivatives
Metabolism of carbohydrates and carbohydrate derivatives Pathway Hierarchies & Genes CS-GAG biosynthesis (5 genes) Metabolism Metabolism of carbohydrates and carbohydrate derivatives Glycosaminoglycan metabolism Chondroitin sulfate/dermatan sulfate metabolism CS-GAG biosynthesis 5 genes HS-GAG biosynthesis (6 genes) Metabolism Metabolism of carbohydrates and carbohydrate derivatives Glycosaminoglycan metabolism Heparan sulfate/heparin (HS-GAG) metabolism HS-GAG biosynthesis 6 genes Hyaluronan degradation (1 genes) Metabolism Metabolism of carbohydrates and carbohydrate derivatives Glycosaminoglycan metabolism Hyaluronan metabolism Hyaluronan degradation 1 genes Keratan sulfate biosynthesis (1 genes) Metabolism Metabolism of carbohydrates and carbohydrate derivatives Glycosaminoglycan metabolism Keratan sulfate/keratin metabolism Keratan sulfate biosynthesis 1 genes Regulation of Glucokinase by Glucokinase Regulatory Protein (1 genes) Metabolism Metabolism of carbohydrates and carbohydrate derivatives Glucose metabolism Glycolysis Regulation of Glucokinase by Glucokinase Regulatory Protein 1 genes Glycolysis (1 genes) Metabolism Metabolism of carbohydrates and carbohydrate derivatives Glucose metabolism Glycolysis 1 genes	Cd44 Gene Information Basic Information Ensembl ID: ENSMUSG00000005087 Description: CD44 antigen [Source:MGI Symbol;Acc:MGI:88338] Location: 2:102641486-102732010 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell phagocyte monocyte granulocyte neutrophil macrophage progenitor cell Other: Cell surface interactions at the vascular wall Integrin cell surface interactions Innate Immune System Chst9 Gene Information Basic Information Ensembl ID: ENSMUSG00000047161 Description: carbohydrate sulfotransferase 9 [Source:MGI Symbol;Acc:MGI:1918617] Location: 18:15584981-15893214 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell bipolar cell neuron Other: Metabolism of carbohydrates and carbohydrate derivatives Cspg5 Gene Information Basic Information Ensembl ID: ENSMUSG00000032482 Description: chondroitin sulfate proteoglycan 5 [Source:MGI Symbol;Acc:MGI:1352747] Location: 9:110072851-110091644 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell oligodendrocyte precursor cell Other: Metabolism of carbohydrates and carbohydrate derivatives Dcn Gene Information Basic Information Ensembl ID: ENSMUSG00000019929 Description: decorin [Source:MGI Symbol;Acc:MGI:94872] Location: 10:97315471-97354005 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell pericyte stem cell stromal cell epithelial cell dendritic cell Other: Degradation of the extracellular matrix ECM proteoglycans Metabolism of carbohydrates and carbohydrate derivatives Gpc3 Gene Information Basic Information Ensembl ID: ENSMUSG00000055653 Description: glypican 3 [Source:MGI Symbol;Acc:MGI:104903] Location: X:51361303-51702827 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell stromal cell embryonic cell fibroblast epithelial cell Other: Metabolism of vitamins and cofactors Visual phototransduction Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Gpc5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022112 Description: glypican 5 [Source:MGI Symbol;Acc:MGI:1194894] Location: 14:115329647-116762591 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell oligodendrocyte precursor cell Other: Metabolism of vitamins and cofactors Visual phototransduction Signaling by Hedgehog Hs3st2 Gene Information Basic Information Ensembl ID: ENSMUSG00000046321 Description: heparan sulfate (glucosamine) 3-O-sulfotransferase 2 [Source:MGI Symbol;Acc:MGI:1333802] Location: 7:120991082-121100993 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of carbohydrates and carbohydrate derivatives Hs3st3b1 Gene Information Basic Information Ensembl ID: ENSMUSG00000070407 Description: heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 [Source:MGI Symbol;Acc:MGI:1333853] Location: 11:63776618-63813116 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stellate cell Other: Metabolism of carbohydrates and carbohydrate derivatives Hs3st4 Gene Information Basic Information Ensembl ID: ENSMUSG00000078591 Description: heparan sulfate (glucosamine) 3-O-sulfotransferase 4 [Source:MGI Symbol;Acc:MGI:1333792] Location: 7:123582092-123998212 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stem cell excitatory neuron Other: Metabolism of carbohydrates and carbohydrate derivatives Ndst4 Gene Information Basic Information Ensembl ID: ENSMUSG00000027971 Description: N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4 [Source:MGI Symbol;Acc:MGI:1932545] Location: 3:125197725-125522548 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cajal-retzius cell Other: Metabolism of carbohydrates and carbohydrate derivatives Pfkm Gene Information Basic Information Ensembl ID: ENSMUSG00000033065 Description: phosphofructokinase%2C muscle [Source:MGI Symbol;Acc:MGI:97548] Location: 15:97990470-98030332 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: skeletal muscle cell Other: Metabolism of carbohydrates and carbohydrate derivatives Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress St3gal1 Gene Information Basic Information Ensembl ID: ENSMUSG00000013846 Description: ST3 beta-galactoside alpha-2%2C3-sialyltransferase 1 [Source:MGI Symbol;Acc:MGI:98304] Location: 15:66974724-67048679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Post-translational protein modification Metabolism of carbohydrates and carbohydrate derivatives Ust Gene Information Basic Information Ensembl ID: ENSMUSG00000047712 Description: uronyl-2-sulfotransferase [Source:MGI Symbol;Acc:MGI:2442406] Location: 10:8080520-8394589 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell epithelial cell fibroblast glial cell mesenchymal cell Other: Metabolism of carbohydrates and carbohydrate derivatives Vcan Gene Information Basic Information Ensembl ID: ENSMUSG00000021614 Description: versican [Source:MGI Symbol;Acc:MGI:102889] Location: 13:89803431-89890628 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast glial cell oligodendrocyte precursor cell epithelial cell monocyte pericyte mural cell Other: ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification
Metabolism of lipids Pathway Hierarchies & Genes Biosynthesis of DPAn-3 SPMs (1 genes) Metabolism Metabolism of lipids Fatty acid metabolism Arachidonate metabolism Synthesis of 15-eicosatetraenoic acid derivatives Biosynthesis of specialized proresolving mediators (SPMs) Biosynthesis of DPA-derived SPMs Biosynthesis of DPAn-3 SPMs 1 genes Biosynthesis of Lipoxins (LX) (1 genes) Metabolism Metabolism of lipids Fatty acid metabolism Arachidonate metabolism Synthesis of 5-eicosatetraenoic acids Biosynthesis of specialized proresolving mediators (SPMs) Biosynthesis of Lipoxins (LX) 1 genes Androgen biosynthesis (1 genes) Metabolism Metabolism of lipids Metabolism of steroids Metabolism of steroid hormones Androgen biosynthesis 1 genes Glycerophospholipid catabolism (1 genes) Metabolism Metabolism of lipids Phospholipid metabolism PI Metabolism Glycerophospholipid catabolism 1 genes Glycosphingolipid biosynthesis (2 genes) Metabolism Metabolism of lipids Sphingolipid metabolism Glycosphingolipid metabolism Glycosphingolipid biosynthesis 2 genes Glycosphingolipid catabolism (1 genes) Metabolism Metabolism of lipids Sphingolipid metabolism Glycosphingolipid metabolism Glycosphingolipid catabolism 1 genes Synthesis of PC (2 genes) Metabolism Metabolism of lipids Phospholipid metabolism Glycerophospholipid biosynthesis Synthesis of PC 2 genes Synthesis of PIPs at the plasma membrane (2 genes) Metabolism Metabolism of lipids Phospholipid metabolism PI Metabolism Synthesis of PIPs at the plasma membrane 2 genes Synthesis of bile acids and bile salts (1 genes) Metabolism Metabolism of lipids Metabolism of steroids Bile acid and bile salt metabolism Synthesis of bile acids and bile salts 1 genes Carnitine shuttle (1 genes) Metabolism Metabolism of lipids Fatty acid metabolism Carnitine shuttle 1 genes Sphingolipid de novo biosynthesis (1 genes) Metabolism Metabolism of lipids Sphingolipid metabolism Sphingolipid de novo biosynthesis 1 genes Lipid particle organization (1 genes) Metabolism Metabolism of lipids Lipid particle organization 1 genes	Alox5ap Gene Information Basic Information Ensembl ID: ENSMUSG00000060063 Description: arachidonate 5-lipoxygenase activating protein [Source:MGI Symbol;Acc:MGI:107505] Location: 5:149201577-149224963 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell dendritic cell phagocyte tuft cell granulocyte eosinophil monocyte myeloid cell T cell macrophage leukocyte Other: Metabolism of lipids Chat Gene Information Basic Information Ensembl ID: ENSMUSG00000021919 Description: choline O-acetyltransferase [Source:MGI Symbol;Acc:MGI:88392] Location: 14:32130160-32187946 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: tuft cell motor neuron Other: Transmission across Chemical Synapses Metabolism of lipids Cidea Gene Information Basic Information Ensembl ID: ENSMUSG00000024526 Description: cell death-inducing DNA fragmentation factor%2C alpha subunit-like effector A [Source:MGI Symbol;Acc:MGI:1270845] Location: 18:67476674-67500855 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of lipids Enpp6 Gene Information Basic Information Ensembl ID: ENSMUSG00000038173 Description: ectonucleotide pyrophosphatase/phosphodiesterase 6 [Source:MGI Symbol;Acc:MGI:2445171] Location: 8:47439922-47549797 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocardial cell oligodendrocyte precursor cell Other: Metabolism of lipids Fa2h Gene Information Basic Information Ensembl ID: ENSMUSG00000033579 Description: fatty acid 2-hydroxylase [Source:MGI Symbol;Acc:MGI:2443327] Location: 8:112071767-112120456 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell glial cell Other: Metabolism of lipids Osbpl3 Gene Information Basic Information Ensembl ID: ENSMUSG00000029822 Description: oxysterol binding protein-like 3 [Source:MGI Symbol;Acc:MGI:1918970] Location: 6:50270310-50433181 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell Specialized T cell Other: Metabolism of lipids Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Pomc Gene Information Basic Information Ensembl ID: ENSMUSG00000020660 Description: pro-opiomelanocortin-alpha [Source:MGI Symbol;Acc:MGI:97742] Location: 12:4004951-4010642 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Biological oxidations Peptide hormone metabolism Signaling by GPCR Prkaa2 Gene Information Basic Information Ensembl ID: ENSMUSG00000028518 Description: protein kinase%2C AMP-activated%2C alpha 2 catalytic subunit [Source:MGI Symbol;Acc:MGI:1336173] Location: 4:104887071-104967087 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Macroautophagy Integration of energy metabolism MTOR signalling Pten Gene Information Basic Information Ensembl ID: ENSMUSG00000013663 Description: phosphatase and tensin homolog [Source:MGI Symbol;Acc:MGI:109583] Location: 19:32734897-32803560 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Inositol phosphate metabolism Metabolism of lipids Ptgs2 Gene Information Basic Information Ensembl ID: ENSMUSG00000032487 Description: prostaglandin-endoperoxide synthase 2 [Source:MGI Symbol;Acc:MGI:97798] Location: 1:149975782-149983978 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell granulocyte tuft cell Other: Metabolism of lipids Slc44a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028412 Description: solute carrier family 44%2C member 1 [Source:MGI Symbol;Acc:MGI:2140592] Location: 4:53440413-53622478 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: SLC-mediated transmembrane transport Metabolism of lipids Metabolism of amino acids and derivatives Smpd3 Gene Information Basic Information Ensembl ID: ENSMUSG00000031906 Description: sphingomyelin phosphodiesterase 3%2C neutral [Source:MGI Symbol;Acc:MGI:1927578] Location: 8:106979180-107064620 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell fibroblast osteoblast Other: Metabolism of lipids Death Receptor Signaling St6galnac5 Gene Information Basic Information Ensembl ID: ENSMUSG00000039037 Description: ST6 (alpha-N-acetyl-neuraminyl-2%2C3-beta-galactosyl-1%2C3)-N-acetylgalactosaminide alpha-2%2C6-sialyltransferase 5 [Source:MGI Symbol;Acc:MGI:1349471] Location: 3:152522718-152687883 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron motor neuron adipocyte Other: Metabolism of lipids Post-translational protein modification Ugt8a Gene Information Basic Information Ensembl ID: ENSMUSG00000032854 Description: UDP galactosyltransferase 8A [Source:MGI Symbol;Acc:MGI:109522] Location: 3:125658920-125732268 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell schwann cell oligodendrocyte precursor cell Other: Metabolism of lipids
Metabolism of nitric oxide: NOS3 activation and regulation Pathway Hierarchies & Genes eNOS activation (1 genes) Metabolism Metabolism of nitric oxide: NOS3 activation and regulation eNOS activation 1 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH
Metabolism of non-coding RNA Pathway Hierarchies & Genes snRNP Assembly (1 genes) Metabolism of RNA Metabolism of non-coding RNA snRNP Assembly 1 genes	Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress
Metabolism of nucleotides Pathway Hierarchies & Genes Purine catabolism (1 genes) Metabolism Metabolism of nucleotides Nucleotide catabolism Purine catabolism 1 genes Purine ribonucleoside monophosphate biosynthesis (1 genes) Metabolism Metabolism of nucleotides Nucleotide biosynthesis Purine ribonucleoside monophosphate biosynthesis 1 genes Interconversion of nucleotide di- and triphosphates (1 genes) Metabolism Metabolism of nucleotides Interconversion of nucleotide di- and triphosphates 1 genes Nucleotide catabolism (1 genes) Metabolism Metabolism of nucleotides Nucleotide catabolism 1 genes	Adss1 Gene Information Basic Information Ensembl ID: ENSMUSG00000011148 Description: adenylosuccinate synthase 1 [Source:MGI Symbol;Acc:MGI:87947] Location: 12:112586479-112607794 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bone cell monocyte Other: Metabolism of nucleotides Ak5 Gene Information Basic Information Ensembl ID: ENSMUSG00000039058 Description: adenylate kinase 5 [Source:MGI Symbol;Acc:MGI:2677491] Location: 3:152168452-152373997 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron retinal pigment epithelial cell Other: Metabolism of nucleotides Gda Gene Information Basic Information Ensembl ID: ENSMUSG00000058624 Description: guanine deaminase [Source:MGI Symbol;Acc:MGI:95678] Location: 19:21368671-21450809 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell epithelial cell hematopoietic stem cell phagocyte neuron granulocyte erythroid lineage cell monocyte macrophage Other: Metabolism of nucleotides Samhd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027639 Description: SAM domain and HD domain%2C 1 [Source:MGI Symbol;Acc:MGI:1927468] Location: 2:156939453-156977185 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell phagocyte monocyte Other: Metabolism of nucleotides
Metabolism of vitamins and cofactors Pathway Hierarchies & Genes Metabolism of folate and pterines (1 genes) Metabolism Metabolism of vitamins and cofactors Metabolism of water-soluble vitamins and cofactors Metabolism of folate and pterines 1 genes Molybdenum cofactor biosynthesis (1 genes) Metabolism Metabolism of vitamins and cofactors Metabolism of water-soluble vitamins and cofactors Molybdenum cofactor biosynthesis 1 genes Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (1 genes) Metabolism Metabolism of vitamins and cofactors Metabolism of cofactors Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation 1 genes Metabolism of fat-soluble vitamins (4 genes) Metabolism Metabolism of vitamins and cofactors Metabolism of fat-soluble vitamins 4 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Aldh1l1 Gene Information Basic Information Ensembl ID: ENSMUSG00000030088 Description: aldehyde dehydrogenase 1 family%2C member L1 [Source:MGI Symbol;Acc:MGI:1340024] Location: 6:90463409-90577185 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: astrocyte Other: Metabolism of vitamins and cofactors Gpc3 Gene Information Basic Information Ensembl ID: ENSMUSG00000055653 Description: glypican 3 [Source:MGI Symbol;Acc:MGI:104903] Location: X:51361303-51702827 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell stromal cell embryonic cell fibroblast epithelial cell Other: Metabolism of vitamins and cofactors Visual phototransduction Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Gpc5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022112 Description: glypican 5 [Source:MGI Symbol;Acc:MGI:1194894] Location: 14:115329647-116762591 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell oligodendrocyte precursor cell Other: Metabolism of vitamins and cofactors Visual phototransduction Signaling by Hedgehog Gphn Gene Information Basic Information Ensembl ID: ENSMUSG00000047454 Description: gephyrin [Source:MGI Symbol;Acc:MGI:109602] Location: 12:78273153-78731546 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell epithelial cell Other: Metabolism of vitamins and cofactors Lpl Gene Information Basic Information Ensembl ID: ENSMUSG00000015568 Description: lipoprotein lipase [Source:MGI Symbol;Acc:MGI:96820] Location: 8:69333143-69360100 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: preadipocyte phagocyte fibroblast epithelial cell stromal cell erythrocyte dendritic cell macrophage endothelial cell antigen presenting cell adipocyte Other: Plasma lipoprotein assembly, remodeling, and clearance Metabolism of vitamins and cofactors Visual phototransduction Rbp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000024990 Description: retinol binding protein 4%2C plasma [Source:MGI Symbol;Acc:MGI:97879] Location: 19:38105077-38113729 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell stromal cell epithelial cell enteroendocrine cell hepatocyte Other: Metabolism of vitamins and cofactors Visual phototransduction
Myogenesis Pathway Hierarchies & Genes Myogenesis (2 genes) Developmental Biology Myogenesis 2 genes	Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress
Nephrin family interactions Pathway Hierarchies & Genes Nephrin family interactions (1 genes) Cell-Cell communication Nephrin family interactions 1 genes	Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system
Nervous system development Pathway Hierarchies & Genes Sema4D induced cell migration and growth-cone collapse (1 genes) Developmental Biology Nervous system development Axon guidance Semaphorin interactions Sema4D in semaphorin signaling Sema4D induced cell migration and growth-cone collapse 1 genes Sema4D mediated inhibition of cell attachment and migration (2 genes) Developmental Biology Nervous system development Axon guidance Semaphorin interactions Sema4D in semaphorin signaling Sema4D mediated inhibition of cell attachment and migration 2 genes DSCAM interactions (1 genes) Developmental Biology Nervous system development Axon guidance Netrin-1 signaling DSCAM interactions 1 genes EPH-ephrin mediated repulsion of cells (2 genes) Developmental Biology Nervous system development Axon guidance EPH-Ephrin signaling EPH-ephrin mediated repulsion of cells 2 genes EPHA-mediated growth cone collapse (4 genes) Developmental Biology Nervous system development Axon guidance EPH-Ephrin signaling EPHA-mediated growth cone collapse 4 genes EPHB-mediated forward signaling (6 genes) Developmental Biology Nervous system development Axon guidance EPH-Ephrin signaling EPHB-mediated forward signaling 6 genes Ephrin signaling (1 genes) Developmental Biology Nervous system development Axon guidance EPH-Ephrin signaling Ephrin signaling 1 genes NCAM1 interactions (1 genes) Developmental Biology Nervous system development Axon guidance NCAM signaling for neurite out-growth NCAM1 interactions 1 genes Neurofascin interactions (1 genes) Developmental Biology Nervous system development Axon guidance L1CAM interactions Neurofascin interactions 1 genes Other semaphorin interactions (5 genes) Developmental Biology Nervous system development Axon guidance Semaphorin interactions Other semaphorin interactions 5 genes Recycling pathway of L1 (2 genes) Developmental Biology Nervous system development Axon guidance L1CAM interactions Recycling pathway of L1 2 genes Role of ABL in ROBO-SLIT signaling (1 genes) Developmental Biology Nervous system development Axon guidance Signaling by ROBO receptors Role of ABL in ROBO-SLIT signaling 1 genes Sema3A PAK dependent Axon repulsion (1 genes) Developmental Biology Nervous system development Axon guidance Semaphorin interactions Sema3A PAK dependent Axon repulsion 1 genes Signal transduction by L1 (2 genes) Developmental Biology Nervous system development Axon guidance L1CAM interactions Signal transduction by L1 2 genes Netrin-1 signaling (1 genes) Developmental Biology Nervous system development Axon guidance Netrin-1 signaling 1 genes RET signaling (7 genes) Developmental Biology Nervous system development Axon guidance RET signaling 7 genes Reelin signalling pathway (2 genes) Developmental Biology Nervous system development Axon guidance Reelin signalling pathway 2 genes Signaling by ROBO receptors (3 genes) Developmental Biology Nervous system development Axon guidance Signaling by ROBO receptors 3 genes	Arhgef7 Gene Information Basic Information Ensembl ID: ENSMUSG00000031511 Description: Rho guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1860493] Location: 8:11777721-11885219 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell smooth muscle cell Other: Signaling by GPCR Death Receptor Signaling Signaling by Receptor Tyrosine Kinases Col5a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026837 Description: collagen%2C type V%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88457] Location: 2:27776437-27929526 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell epithelial cell Other: Integrin cell surface interactions Degradation of the extracellular matrix Collagen formation Cxcl12 Gene Information Basic Information Ensembl ID: ENSMUSG00000061353 Description: C-X-C motif chemokine ligand 12 [Source:MGI Symbol;Acc:MGI:103556] Location: 6:117145496-117158328 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stellate cell epithelial cell fibroblast stromal cell smooth muscle cell Other: Signaling by GPCR Nervous system development Cxcr4 Gene Information Basic Information Ensembl ID: ENSMUSG00000045382 Description: C-X-C motif chemokine receptor 4 [Source:MGI Symbol;Acc:MGI:109563] Location: 1:128515936-128520030 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell mast cell monocyte eosinophil progenitor cell Other: Signaling by GPCR Nervous system development Dab1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028519 Description: disabled 1 [Source:MGI Symbol;Acc:MGI:108554] Location: 4:103476556-104602041 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron bipolar cell Other: Nervous system development Dnm1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026825 Description: dynamin 1 [Source:MGI Symbol;Acc:MGI:107384] Location: 2:32198483-32243350 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Innate Immune System Membrane Trafficking Dscaml1 Gene Information Basic Information Ensembl ID: ENSMUSG00000032087 Description: DS cell adhesion molecule like 1 [Source:MGI Symbol;Acc:MGI:2150309] Location: 9:45337926-45665010 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron projection neuron Other: Nervous system development Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Epha4 Gene Information Basic Information Ensembl ID: ENSMUSG00000026235 Description: Eph receptor A4 [Source:MGI Symbol;Acc:MGI:98277] Location: 1:77343822-77491725 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Nervous system development Epha6 Gene Information Basic Information Ensembl ID: ENSMUSG00000055540 Description: Eph receptor A6 [Source:MGI Symbol;Acc:MGI:108034] Location: 16:59473846-60425894 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron retina cell projection neuron Other: Nervous system development Epha7 Gene Information Basic Information Ensembl ID: ENSMUSG00000028289 Description: Eph receptor A7 [Source:MGI Symbol;Acc:MGI:95276] Location: 4:28813131-28967499 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Ephb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000032537 Description: Eph receptor B1 [Source:MGI Symbol;Acc:MGI:1096337] Location: 9:101799327-102231892 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron Other: Nervous system development Ephb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000028664 Description: Eph receptor B2 [Source:MGI Symbol;Acc:MGI:99611] Location: 4:136374850-136563299 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Nervous system development Ephb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000005958 Description: Eph receptor B3 [Source:MGI Symbol;Acc:MGI:104770] Location: 16:21023505-21042055 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Nervous system development Ephb6 Gene Information Basic Information Ensembl ID: ENSMUSG00000029869 Description: Eph receptor B6 [Source:MGI Symbol;Acc:MGI:1096338] Location: 6:41582416-41597443 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stem cell Other: Nervous system development Erbb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000062312 Description: erb-b2 receptor tyrosine kinase 2 [Source:MGI Symbol;Acc:MGI:95410] Location: 11:98303296-98328542 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Gdnf Gene Information Basic Information Ensembl ID: ENSMUSG00000022144 Description: glial cell line derived neurotrophic factor [Source:MGI Symbol;Acc:MGI:107430] Location: 15:7840327-7867056 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades Nervous system development Gfra1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025089 Description: glial cell line derived neurotrophic factor family receptor alpha 1 [Source:MGI Symbol;Acc:MGI:1100842] Location: 19:58224036-58444341 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell stem cell Other: MAPK family signaling cascades Nervous system development Grin1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026959 Description: glutamate receptor%2C ionotropic%2C NMDA1 (zeta 1) [Source:MGI Symbol;Acc:MGI:95819] Location: 2:25181193-25209199 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses MAPK family signaling cascades Protein-protein interactions at synapses Irs2 Gene Information Basic Information Ensembl ID: ENSMUSG00000038894 Description: insulin receptor substrate 2 [Source:MGI Symbol;Acc:MGI:109334] Location: 8:11034681-11058458 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mural cell Other: Cytokine Signaling in Immune system MAPK family signaling cascades Signaling by Erythropoietin Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Met Gene Information Basic Information Ensembl ID: ENSMUSG00000009376 Description: met proto-oncogene [Source:MGI Symbol;Acc:MGI:96969] Location: 6:17463799-17573979 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell intercalated cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Mmp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031740 Description: matrix metallopeptidase 2 [Source:MGI Symbol;Acc:MGI:97009] Location: 8:93553919-93580048 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Degradation of the extracellular matrix Signaling by Nuclear Receptors Nervous system development Nfasc Gene Information Basic Information Ensembl ID: ENSMUSG00000026442 Description: neurofascin [Source:MGI Symbol;Acc:MGI:104753] Location: 1:132492428-132669535 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron bipolar cell astrocyte Other: Innate Immune System Nervous system development Ngef Gene Information Basic Information Ensembl ID: ENSMUSG00000026259 Description: neuronal guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1858414] Location: 1:87404556-87501592 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Death Receptor Signaling Nervous system development Nrp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025810 Description: neuropilin 1 [Source:MGI Symbol;Acc:MGI:106206] Location: 8:129085085-129229844 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell Other: Signaling by Receptor Tyrosine Kinases Nervous system development Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Plxnb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000031385 Description: plexin B3 [Source:MGI Symbol;Acc:MGI:2154240] Location: X:72800696-72816120 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: oligodendrocyte precursor cell Other: Nervous system development Prkcq Gene Information Basic Information Ensembl ID: ENSMUSG00000026778 Description: protein kinase C%2C theta [Source:MGI Symbol;Acc:MGI:97601] Location: 2:11176919-11306033 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell CD8+ T cell Specialized T cell Other: Apoptosis Adaptive Immune System Innate Immune System Psen1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019969 Description: presenilin 1 [Source:MGI Symbol;Acc:MGI:1202717] Location: 12:83734926-83781973 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by NOTCH Death Receptor Signaling Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Ptprc Gene Information Basic Information Ensembl ID: ENSMUSG00000026395 Description: protein tyrosine phosphatase receptor type C [Source:MGI Symbol;Acc:MGI:97810] Location: 1:137990599-138103446 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell phagocyte monocyte CD8+ T cell T cell Specialized T cell leukocyte lymphocyte hematopoietic cell myeloid cell immune cell Naive B cell epithelial cell Follicular B cell hematopoietic stem cell memory B cell Other: Innate Immune System Adaptive Immune System Nervous system development Rap1gap Gene Information Basic Information Ensembl ID: ENSMUSG00000041351 Description: Rap1 GTPase-activating protein [Source:MGI Symbol;Acc:MGI:109338] Location: 4:137392037-137457172 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pancreatic cell oligodendrocyte precursor cell Other: Adaptive Immune System Nervous system development Reln Gene Information Basic Information Ensembl ID: ENSMUSG00000042453 Description: reelin [Source:MGI Symbol;Acc:MGI:103022] Location: 5:22089452-22549700 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stellate cell neuron glial cell sensory neuron inhibitory neuron cajal-retzius cell Other: Nervous system development Ret Gene Information Basic Information Ensembl ID: ENSMUSG00000030110 Description: ret proto-oncogene [Source:MGI Symbol;Acc:MGI:97902] Location: 6:118128706-118174679 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron autonomic neuron Other: MAPK family signaling cascades Nervous system development Sema3e Gene Information Basic Information Ensembl ID: ENSMUSG00000063531 Description: sema domain%2C immunoglobulin domain (Ig)%2C short basic domain%2C secreted%2C (semaphorin) 3E [Source:MGI Symbol;Acc:MGI:1340034] Location: 5:14075290-14306703 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell pneumocyte Other: Nervous system development Sema4d Gene Information Basic Information Ensembl ID: ENSMUSG00000021451 Description: sema domain%2C immunoglobulin domain (Ig)%2C transmembrane domain (TM) and short cytoplasmic domain%2C (semaphorin) 4D [Source:MGI Symbol;Acc:MGI:109244] Location: 13:51839565-51947783 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell Other: Nervous system development Sema5a Gene Information Basic Information Ensembl ID: ENSMUSG00000022231 Description: sema domain%2C seven thrombospondin repeats (type 1 and type 1-like)%2C transmembrane domain (TM) and short cytoplasmic domain%2C (semaphorin) 5A [Source:MGI Symbol;Acc:MGI:107556] Location: 15:32244956-32696487 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell fibroblast neuron Other: Post-translational protein modification Nervous system development Sema6d Gene Information Basic Information Ensembl ID: ENSMUSG00000027200 Description: sema domain%2C transmembrane domain (TM)%2C and cytoplasmic domain%2C (semaphorin) 6D [Source:MGI Symbol;Acc:MGI:2387661] Location: 2:123931889-124509690 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell pericyte stellate cell oligodendrocyte precursor cell Other: Nervous system development Slit2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031558 Description: slit guidance ligand 2 [Source:MGI Symbol;Acc:MGI:1315205] Location: 5:48140480-48465075 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell fibroblast motor neuron Other: Nervous system development Slit3 Gene Information Basic Information Ensembl ID: ENSMUSG00000056427 Description: slit guidance ligand 3 [Source:MGI Symbol;Acc:MGI:1315202] Location: 11:35012051-35599334 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: modulatory neuron Other: Nervous system development
Non-integrin membrane-ECM interactions Pathway Hierarchies & Genes Syndecan interactions (7 genes) Extracellular matrix organization Non-integrin membrane-ECM interactions 3 genes Syndecan interactions 4 genes	Acta2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035783 Description: actin alpha 2%2C smooth muscle%2C aorta [Source:MGI Symbol;Acc:MGI:87909] Location: 19:34218490-34232990 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stellate cell endothelial cell stem cell smooth muscle cell fibroblast mural cell mesangial cell progenitor cell muscle cell mesenchymal cell Other: Non-integrin membrane-ECM interactions Smooth Muscle Contraction Cell junction organization Col11a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027966 Description: collagen%2C type XI%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88446] Location: 3:113824189-114014367 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell Other: Degradation of the extracellular matrix Collagen formation Non-integrin membrane-ECM interactions Col5a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026837 Description: collagen%2C type V%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88457] Location: 2:27776437-27929526 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell epithelial cell Other: Integrin cell surface interactions Degradation of the extracellular matrix Collagen formation Ddr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000003534 Description: discoidin domain receptor family%2C member 1 [Source:MGI Symbol;Acc:MGI:99216] Location: 17:35992459-36015513 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Non-integrin membrane-ECM interactions Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Sntg2 Gene Information Basic Information Ensembl ID: ENSMUSG00000020672 Description: syntrophin%2C gamma 2 [Source:MGI Symbol;Acc:MGI:1919541] Location: 12:30224481-30423374 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Non-integrin membrane-ECM interactions Tgfb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000002603 Description: transforming growth factor%2C beta 1 [Source:MGI Symbol;Acc:MGI:98725] Location: 7:25386427-25404502 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell hematopoietic stem cell phagocyte monocyte leukocyte megakaryocyte Other: Cell surface interactions at the vascular wall Non-integrin membrane-ECM interactions Elastic fibre formation
Nonsense-Mediated Decay (NMD) Pathway Hierarchies & Genes Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (1 genes) Metabolism of RNA Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) 1 genes	Ppp2r2a Gene Information Basic Information Ensembl ID: ENSMUSG00000022052 Description: protein phosphatase 2%2C regulatory subunit B%2C alpha [Source:MGI Symbol;Acc:MGI:1919228] Location: 14:67251505-67309893 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: adrenal cortical cell Other: Cell Cycle, Mitotic Nonsense-Mediated Decay (NMD) Cellular responses to mechanical stimuli
O2/CO2 exchange in erythrocytes Pathway Hierarchies & Genes Erythrocytes take up oxygen and release carbon dioxide (2 genes) Transport of small molecules O2/CO2 exchange in erythrocytes Erythrocytes take up carbon dioxide and release oxygen Erythrocytes take up oxygen and release carbon dioxide 2 genes	Aqp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000004655 Description: aquaporin 1 [Source:MGI Symbol;Acc:MGI:103201] Location: 6:55313417-55325540 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell hematopoietic progenitor cell erythroblast podocyte Other: O2/CO2 exchange in erythrocytes Aquaporin-mediated transport Car4 Gene Information Basic Information Ensembl ID: ENSMUSG00000000805 Description: carbonic anhydrase 4 [Source:MGI Symbol;Acc:MGI:1096574] Location: 11:84848612-84856870 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell epithelial cell smooth muscle cell eosinophil Other: Reversible hydration of carbon dioxide O2/CO2 exchange in erythrocytes
Olfactory Signaling Pathway Pathway Hierarchies & Genes Olfactory Signaling Pathway (1 genes) Sensory Perception Olfactory Signaling Pathway 1 genes	Gnal Gene Information Basic Information Ensembl ID: ENSMUSG00000024524 Description: guanine nucleotide binding protein%2C alpha stimulating%2C olfactory type [Source:MGI Symbol;Acc:MGI:95774] Location: 18:67221287-67359863 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Signaling by GPCR Olfactory Signaling Pathway
Peptide hormone metabolism Pathway Hierarchies & Genes Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (1 genes) Metabolism of proteins Peptide hormone metabolism Incretin synthesis, secretion, and inactivation Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) 1 genes Peptide hormone biosynthesis (1 genes) Metabolism of proteins Peptide hormone metabolism Peptide hormone biosynthesis 1 genes Synthesis, secretion, and deacylation of Ghrelin (2 genes) Metabolism of proteins Peptide hormone metabolism Synthesis, secretion, and deacylation of Ghrelin 2 genes	Bche Gene Information Basic Information Ensembl ID: ENSMUSG00000027792 Description: butyrylcholinesterase [Source:MGI Symbol;Acc:MGI:894278] Location: 3:73543141-73615748 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Peptide hormone metabolism Aspirin ADME Grp Gene Information Basic Information Ensembl ID: ENSMUSG00000024517 Description: gastrin releasing peptide [Source:MGI Symbol;Acc:MGI:95833] Location: 18:66005891-66019667 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: basal cell Other: Peptide hormone metabolism Signaling by GPCR Igf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020053 Description: insulin-like growth factor 1 [Source:MGI Symbol;Acc:MGI:96432] Location: 10:87694127-87772904 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell interneuron phagocyte smooth muscle cell epithelial cell stromal cell macrophage dendritic cell Other: Peptide hormone metabolism Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Platelet activation, signaling and aggregation Pomc Gene Information Basic Information Ensembl ID: ENSMUSG00000020660 Description: pro-opiomelanocortin-alpha [Source:MGI Symbol;Acc:MGI:97742] Location: 12:4004951-4010642 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Biological oxidations Peptide hormone metabolism Signaling by GPCR
Plasma lipoprotein assembly, remodeling, and clearance Pathway Hierarchies & Genes Assembly of active LPL and LIPC lipase complexes (2 genes) Transport of small molecules Plasma lipoprotein assembly, remodeling, and clearance Plasma lipoprotein remodeling Assembly of active LPL and LIPC lipase complexes 2 genes HDL remodeling (1 genes) Transport of small molecules Plasma lipoprotein assembly, remodeling, and clearance Plasma lipoprotein remodeling HDL remodeling 1 genes	Lcat Gene Information Basic Information Ensembl ID: ENSMUSG00000035237 Description: lecithin cholesterol acyltransferase [Source:MGI Symbol;Acc:MGI:96755] Location: 8:106666183-106670014 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: astrocyte Other: Plasma lipoprotein assembly, remodeling, and clearance Lpl Gene Information Basic Information Ensembl ID: ENSMUSG00000015568 Description: lipoprotein lipase [Source:MGI Symbol;Acc:MGI:96820] Location: 8:69333143-69360100 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: preadipocyte phagocyte fibroblast epithelial cell stromal cell erythrocyte dendritic cell macrophage endothelial cell antigen presenting cell adipocyte Other: Plasma lipoprotein assembly, remodeling, and clearance Metabolism of vitamins and cofactors Visual phototransduction Pcsk6 Gene Information Basic Information Ensembl ID: ENSMUSG00000030513 Description: proprotein convertase subtilisin/kexin type 6 [Source:MGI Symbol;Acc:MGI:102897] Location: 7:65511482-65700134 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell epithelial cell fibroblast neuron retina cell mesenchymal cell Other: Plasma lipoprotein assembly, remodeling, and clearance Cell junction organization Signaling by Receptor Tyrosine Kinases
Platelet Adhesion to exposed collagen Pathway Hierarchies & Genes Platelet Adhesion to exposed collagen (1 genes) Hemostasis Platelet Adhesion to exposed collagen 1 genes	Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system
Platelet activation, signaling and aggregation Pathway Hierarchies & Genes Platelet Aggregation (Plug Formation) (10 genes) Hemostasis Platelet activation, signaling and aggregation Response to elevated platelet cytosolic Ca2+ Platelet degranulation 9 genes Platelet Aggregation (Plug Formation) 1 genes Thrombin signalling through proteinase activated receptors (PARs) (1 genes) Hemostasis Platelet activation, signaling and aggregation Signal amplification ADP signalling through P2Y purinoceptor 12 Thrombin signalling through proteinase activated receptors (PARs) 1 genes ADP signalling through P2Y purinoceptor 1 (2 genes) Hemostasis Platelet activation, signaling and aggregation Signal amplification ADP signalling through P2Y purinoceptor 1 2 genes Adrenaline signalling through Alpha-2 adrenergic receptor (1 genes) Hemostasis Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) Adrenaline signalling through Alpha-2 adrenergic receptor 1 genes Disinhibition of SNARE formation (2 genes) Hemostasis Platelet activation, signaling and aggregation Response to elevated platelet cytosolic Ca2+ Disinhibition of SNARE formation 2 genes Effects of PIP2 hydrolysis (6 genes) Hemostasis Platelet activation, signaling and aggregation Effects of PIP2 hydrolysis 6 genes GPVI-mediated activation cascade (4 genes) Hemostasis Platelet activation, signaling and aggregation GPVI-mediated activation cascade 4 genes Platelet Aggregation (Plug Formation) (5 genes) Hemostasis Platelet activation, signaling and aggregation Platelet Aggregation (Plug Formation) 5 genes Thrombin signalling through proteinase activated receptors (PARs) (2 genes) Hemostasis Platelet activation, signaling and aggregation Thrombin signalling through proteinase activated receptors (PARs) 2 genes	Adra2c Gene Information Basic Information Ensembl ID: ENSMUSG00000045318 Description: adrenergic receptor%2C alpha 2c [Source:MGI Symbol;Acc:MGI:87936] Location: 5:35435663-35439107 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Integration of energy metabolism Signaling by GPCR Surfactant metabolism Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Anxa5 Gene Information Basic Information Ensembl ID: ENSMUSG00000027712 Description: annexin A5 [Source:MGI Symbol;Acc:MGI:106008] Location: 3:36503072-36530043 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast endocrine cell pericyte stem cell macrophage epithelial cell Other: Platelet activation, signaling and aggregation Apbb1ip Gene Information Basic Information Ensembl ID: ENSMUSG00000026786 Description: amyloid beta precursor protein binding family B member 1 interacting protein [Source:MGI Symbol;Acc:MGI:1861354] Location: 2:22664106-22765665 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte monocyte granulocyte microglia Other: Integrin signaling MAPK family signaling cascades Platelet activation, signaling and aggregation Cd36 Gene Information Basic Information Ensembl ID: ENSMUSG00000002944 Description: CD36 molecule [Source:MGI Symbol;Acc:MGI:107899] Location: 5:17986688-18093799 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macrophage Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Dgkb Gene Information Basic Information Ensembl ID: ENSMUSG00000036095 Description: diacylglycerol kinase%2C beta [Source:MGI Symbol;Acc:MGI:2442474] Location: 12:37867725-38684238 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte glial cell smooth muscle cell Other: Signaling by GPCR Platelet activation, signaling and aggregation Dgkk Gene Information Basic Information Ensembl ID: ENSMUSG00000062393 Description: diacylglycerol kinase kappa [Source:MGI Symbol;Acc:MGI:3580254] Location: X:6690410-6814602 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet activation, signaling and aggregation Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Hgf Gene Information Basic Information Ensembl ID: ENSMUSG00000028864 Description: hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079] Location: 5:16758493-16825150 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell stellate cell eosinophil Other: MAPK family signaling cascades Platelet activation, signaling and aggregation Intracellular signaling by second messengers Igf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020053 Description: insulin-like growth factor 1 [Source:MGI Symbol;Acc:MGI:96432] Location: 10:87694127-87772904 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell interneuron phagocyte smooth muscle cell epithelial cell stromal cell macrophage dendritic cell Other: Peptide hormone metabolism Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Platelet activation, signaling and aggregation Igf2 Gene Information Basic Information Ensembl ID: ENSMUSG00000048583 Description: insulin-like growth factor 2 [Source:MGI Symbol;Acc:MGI:96434] Location: 7:142204503-142220553 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stromal cell fibroblast endothelial cell mesothelial cell endocardial cell Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Platelet activation, signaling and aggregation Signaling by Receptor Tyrosine Kinases Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system P2ry1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027765 Description: purinergic receptor P2Y%2C G-protein coupled 1 [Source:MGI Symbol;Acc:MGI:105049] Location: 3:60910216-60916403 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet activation, signaling and aggregation Pdpn Gene Information Basic Information Ensembl ID: ENSMUSG00000028583 Description: podoplanin [Source:MGI Symbol;Acc:MGI:103098] Location: 4:142994001-143026134 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mesothelial cell pneumocyte lymphocyte pericyte Other: Platelet activation, signaling and aggregation Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Prkcb Gene Information Basic Information Ensembl ID: ENSMUSG00000052889 Description: protein kinase C%2C beta [Source:MGI Symbol;Acc:MGI:97596] Location: 7:121887974-122233625 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron dendritic cell developing T cell Naive B cell monocyte mast cell Other: Transmission across Chemical Synapses Adaptive Immune System Signaling by WNT Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system Prkce Gene Information Basic Information Ensembl ID: ENSMUSG00000045038 Description: protein kinase C%2C epsilon [Source:MGI Symbol;Acc:MGI:97599] Location: 17:86475213-86965347 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by GPCR Platelet activation, signaling and aggregation Prkcg Gene Information Basic Information Ensembl ID: ENSMUSG00000078816 Description: protein kinase C%2C gamma [Source:MGI Symbol;Acc:MGI:97597] Location: 7:3337704-3379615 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Signaling by WNT Signaling by GPCR Prkcq Gene Information Basic Information Ensembl ID: ENSMUSG00000026778 Description: protein kinase C%2C theta [Source:MGI Symbol;Acc:MGI:97601] Location: 2:11176919-11306033 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell CD8+ T cell Specialized T cell Other: Apoptosis Adaptive Immune System Innate Immune System Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Rap1a Gene Information Basic Information Ensembl ID: ENSMUSG00000068798 Description: RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852] Location: 3:105634583-105708652 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell monocyte muscle cell dendritic cell plasma cell megakaryocyte Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Rapgef4 Gene Information Basic Information Ensembl ID: ENSMUSG00000049044 Description: Rap guanine nucleotide exchange factor (GEF) 4 [Source:MGI Symbol;Acc:MGI:1917723] Location: 2:71811584-72087818 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell neuron adrenal cortical cell Other: Adaptive Immune System Integration of energy metabolism Integrin signaling Rasgrp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027347 Description: RAS guanyl releasing protein 1 [Source:MGI Symbol;Acc:MGI:1314635] Location: 2:117110474-117173482 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell Specialized T cell CD4+ T cell neuron Other: Adaptive Immune System Integrin signaling MAPK family signaling cascades Srgn Gene Information Basic Information Ensembl ID: ENSMUSG00000020077 Description: serglycin [Source:MGI Symbol;Acc:MGI:97756] Location: 10:62329612-62363230 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell natural killer cell dendritic cell Regulatory T cell Naive B cell hematopoietic stem cell microglia leukocyte monocyte granulocyte eosinophil lymphocyte immune cell Other: Platelet activation, signaling and aggregation Tgfb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000002603 Description: transforming growth factor%2C beta 1 [Source:MGI Symbol;Acc:MGI:98725] Location: 7:25386427-25404502 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell hematopoietic stem cell phagocyte monocyte leukocyte megakaryocyte Other: Cell surface interactions at the vascular wall Non-integrin membrane-ECM interactions Elastic fibre formation Trpc7 Gene Information Basic Information Ensembl ID: ENSMUSG00000021541 Description: transient receptor potential cation channel%2C subfamily C%2C member 7 [Source:MGI Symbol;Acc:MGI:1349470] Location: 13:56920926-57043806 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet homeostasis Platelet activation, signaling and aggregation Vegfa Gene Information Basic Information Ensembl ID: ENSMUSG00000023951 Description: vascular endothelial growth factor A [Source:MGI Symbol;Acc:MGI:103178] Location: 17:46327919-46343295 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stellate cell mast cell stromal cell Other: Platelet activation, signaling and aggregation Signaling by Receptor Tyrosine Kinases Vegfc Gene Information Basic Information Ensembl ID: ENSMUSG00000031520 Description: vascular endothelial growth factor C [Source:MGI Symbol;Acc:MGI:109124] Location: 8:54530641-54640131 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Platelet activation, signaling and aggregation Signaling by Receptor Tyrosine Kinases
Platelet homeostasis Pathway Hierarchies & Genes Elevation of cytosolic Ca2+ levels (1 genes) Hemostasis Platelet homeostasis Platelet calcium homeostasis Elevation of cytosolic Ca2+ levels 1 genes Reduction of cytosolic Ca++ levels (1 genes) Hemostasis Platelet homeostasis Platelet calcium homeostasis Reduction of cytosolic Ca++ levels 1 genes cGMP effects (3 genes) Hemostasis Platelet homeostasis Nitric oxide stimulates guanylate cyclase cGMP effects 3 genes cGMP effects (5 genes) Hemostasis Platelet homeostasis Nitric oxide stimulates guanylate cyclase 3 genes cGMP effects 2 genes Nitric oxide stimulates guanylate cyclase (1 genes) Hemostasis Platelet homeostasis Nitric oxide stimulates guanylate cyclase 1 genes	Atp2b4 Gene Information Basic Information Ensembl ID: ENSMUSG00000026463 Description: ATPase%2C Ca++ transporting%2C plasma membrane 4 [Source:MGI Symbol;Acc:MGI:88111] Location: 1:133627195-133728779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell hematopoietic progenitor cell Other: Platelet homeostasis Cardiac conduction Ion channel transport Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Irag1 Gene Information Basic Information Ensembl ID: ENSMUSG00000005611 Description: inositol 1%2C4%2C5-triphosphate receptor associated 1 [Source:MGI Symbol;Acc:MGI:1338023] Location: 7:110467473-110581668 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell muscle cell mural cell mesangial cell megakaryocyte Other: Platelet homeostasis Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Nos1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029361 Description: nitric oxide synthase 1%2C neuronal [Source:MGI Symbol;Acc:MGI:97360] Location: 5:117919097-118096905 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: macula densa cell Other: Innate Immune System Platelet homeostasis Cardiac conduction Pde10a Gene Information Basic Information Ensembl ID: ENSMUSG00000023868 Description: phosphodiesterase 10A [Source:MGI Symbol;Acc:MGI:1345143] Location: 17:8744204-9205480 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron stem cell epithelial cell Other: Signaling by GPCR Platelet homeostasis Pde11a Gene Information Basic Information Ensembl ID: ENSMUSG00000075270 Description: phosphodiesterase 11A [Source:MGI Symbol;Acc:MGI:3036251] Location: 2:75819485-76169118 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron enteroendocrine cell Other: Signaling by GPCR Platelet homeostasis Pde1a Gene Information Basic Information Ensembl ID: ENSMUSG00000059173 Description: phosphodiesterase 1A%2C calmodulin-dependent [Source:MGI Symbol;Acc:MGI:1201792] Location: 2:79664797-79959802 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell preadipocyte stellate cell smooth muscle cell neuron Other: Signaling by GPCR Platelet homeostasis Intracellular signaling by second messengers Pde1b Gene Information Basic Information Ensembl ID: ENSMUSG00000022489 Description: phosphodiesterase 1B%2C Ca2+-calmodulin dependent [Source:MGI Symbol;Acc:MGI:97523] Location: 15:103411461-103438479 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet homeostasis Intracellular signaling by second messengers Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Trpc7 Gene Information Basic Information Ensembl ID: ENSMUSG00000021541 Description: transient receptor potential cation channel%2C subfamily C%2C member 7 [Source:MGI Symbol;Acc:MGI:1349470] Location: 13:56920926-57043806 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet homeostasis Platelet activation, signaling and aggregation
Post-translational protein modification Pathway Hierarchies & Genes Termination of O-glycan biosynthesis (2 genes) Metabolism of proteins Post-translational protein modification Asparagine N-linked glycosylation Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Synthesis of substrates in N-glycan biosythesis Sialic acid metabolism 1 genes O-linked glycosylation O-linked glycosylation of mucins Termination of O-glycan biosynthesis 1 genes Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 (1 genes) Metabolism of proteins Post-translational protein modification Asparagine N-linked glycosylation Transport to the Golgi and subsequent modification N-glycan trimming and elongation in the cis-Golgi Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 1 genes Neddylation (5 genes) Metabolism of proteins Post-translational protein modification Deubiquitination Ub-specific processing proteases 4 genes Neddylation 1 genes SUMOylation of DNA damage response and repair proteins (1 genes) Metabolism of proteins Post-translational protein modification SUMOylation SUMO E3 ligases SUMOylate target proteins SUMOylation of DNA damage response and repair proteins 1 genes SUMOylation of DNA replication proteins (1 genes) Metabolism of proteins Post-translational protein modification SUMOylation SUMO E3 ligases SUMOylate target proteins SUMOylation of DNA replication proteins 1 genes SUMOylation of chromatin organization proteins (1 genes) Metabolism of proteins Post-translational protein modification SUMOylation SUMO E3 ligases SUMOylate target proteins SUMOylation of chromatin organization proteins 1 genes SUMOylation of intracellular receptors (1 genes) Metabolism of proteins Post-translational protein modification SUMOylation SUMO E3 ligases SUMOylate target proteins SUMOylation of intracellular receptors 1 genes Josephin domain DUBs (1 genes) Metabolism of proteins Post-translational protein modification Deubiquitination Josephin domain DUBs 1 genes O-glycosylation of TSR domain-containing proteins (6 genes) Metabolism of proteins Post-translational protein modification O-linked glycosylation O-glycosylation of TSR domain-containing proteins 6 genes O-linked glycosylation of mucins (2 genes) Metabolism of proteins Post-translational protein modification O-linked glycosylation O-linked glycosylation of mucins 2 genes Ovarian tumor domain proteases (1 genes) Metabolism of proteins Post-translational protein modification Deubiquitination Ovarian tumor domain proteases 1 genes Transport to the Golgi and subsequent modification (2 genes) Metabolism of proteins Post-translational protein modification Asparagine N-linked glycosylation Transport to the Golgi and subsequent modification 2 genes Neddylation (2 genes) Metabolism of proteins Post-translational protein modification Neddylation 2 genes Post-translational modification: synthesis of GPI-anchored proteins (4 genes) Metabolism of proteins Post-translational protein modification Post-translational modification: synthesis of GPI-anchored proteins 4 genes Post-translational protein phosphorylation (12 genes) Metabolism of proteins Post-translational protein modification Post-translational protein phosphorylation 12 genes Proteasome assembly (1 genes) Metabolism of proteins Post-translational protein modification Proteasome assembly 1 genes RAB geranylgeranylation (2 genes) Metabolism of proteins Post-translational protein modification RAB geranylgeranylation 2 genes	Adamts19 Gene Information Basic Information Ensembl ID: ENSMUSG00000053441 Description: ADAM metallopeptidase with thrombospondin type 1 motif 19 [Source:MGI Symbol;Acc:MGI:2442875] Location: 18:58969739-59187132 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast Other: Post-translational protein modification Adamts2 Gene Information Basic Information Ensembl ID: ENSMUSG00000036545 Description: ADAM metallopeptidase with thrombospondin type 1 motif 2 [Source:MGI Symbol;Acc:MGI:1347356] Location: 11:50492911-50698400 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast epithelial cell osteoblast Other: Collagen formation Post-translational protein modification Adamts9 Gene Information Basic Information Ensembl ID: ENSMUSG00000030022 Description: ADAM metallopeptidase with thrombospondin type 1 motif 9 [Source:MGI Symbol;Acc:MGI:1916320] Location: 6:92749680-92920473 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell pancreatic cell Other: Post-translational protein modification Adamtsl1 Gene Information Basic Information Ensembl ID: ENSMUSG00000066113 Description: ADAMTS-like 1 [Source:MGI Symbol;Acc:MGI:1924989] Location: 4:85432409-86346622 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast epithelial cell pneumocyte glial cell mesenchymal cell Other: Post-translational protein modification Adrb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000045730 Description: adrenergic receptor%2C beta 2 [Source:MGI Symbol;Acc:MGI:87938] Location: 18:62310887-62313030 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell erythroblast Other: Membrane Trafficking Signaling by GPCR Post-translational protein modification Bmp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000021835 Description: bone morphogenetic protein 4 [Source:MGI Symbol;Acc:MGI:88180] Location: 14:46620977-46628126 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stem cell fibroblast epithelial cell smooth muscle cell ectodermal cell endothelial cell mesodermal cell Other: Elastic fibre formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification C3 Gene Information Basic Information Ensembl ID: ENSMUSG00000024164 Description: complement component 3 [Source:MGI Symbol;Acc:MGI:88227] Location: 17:57510970-57535136 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell fibroblast stellate cell stem cell endothelial cell stromal cell epithelial cell hepatocyte Other: Adaptive Immune System Innate Immune System Signaling by GPCR Cftr Gene Information Basic Information Ensembl ID: ENSMUSG00000041301 Description: cystic fibrosis transmembrane conductance regulator [Source:MGI Symbol;Acc:MGI:88388] Location: 6:18170686-18322767 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pneumocyte ionocyte Other: Macroautophagy Membrane Trafficking ABC-family proteins mediated transport Cntn5 Gene Information Basic Information Ensembl ID: ENSMUSG00000039488 Description: contactin 5 [Source:MGI Symbol;Acc:MGI:3042287] Location: 9:9660896-10904780 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron sensory neuron neuron epithelial cell Other: Post-translational protein modification Csf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000014599 Description: colony stimulating factor 1 (macrophage) [Source:MGI Symbol;Acc:MGI:1339753] Location: 3:107648364-107667785 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell basophil eosinophil Other: Cytokine Signaling in Immune system Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Dync1li2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035770 Description: dynein%2C cytoplasmic 1 light intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107738] Location: 8:105144312-105169679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Membrane Trafficking Fbxl16 Gene Information Basic Information Ensembl ID: ENSMUSG00000025738 Description: F-box and leucine-rich repeat protein 16 [Source:MGI Symbol;Acc:MGI:2448488] Location: 17:26028059-26040229 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Post-translational protein modification Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Galnt14 Gene Information Basic Information Ensembl ID: ENSMUSG00000024064 Description: polypeptide N-acetylgalactosaminyltransferase 14 [Source:MGI Symbol;Acc:MGI:1918935] Location: 17:73800223-74017448 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Post-translational protein modification Galnt18 Gene Information Basic Information Ensembl ID: ENSMUSG00000038296 Description: polypeptide N-acetylgalactosaminyltransferase 18 [Source:MGI Symbol;Acc:MGI:2446239] Location: 7:111070868-111379184 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell retina cell astrocyte Other: Post-translational protein modification Gata3 Gene Information Basic Information Ensembl ID: ENSMUSG00000015619 Description: GATA binding protein 3 [Source:MGI Symbol;Acc:MGI:95663] Location: 2:9861889-9894845 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell epithelial cell stem cell CD4+ T cell innate lymphoid cell developing T cell mesangial cell Other: Post-translational protein modification RNA Polymerase II Transcription Signaling by Nuclear Receptors Gpc3 Gene Information Basic Information Ensembl ID: ENSMUSG00000055653 Description: glypican 3 [Source:MGI Symbol;Acc:MGI:104903] Location: X:51361303-51702827 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell stromal cell embryonic cell fibroblast epithelial cell Other: Metabolism of vitamins and cofactors Visual phototransduction Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Gria1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020524 Description: glutamate receptor%2C ionotropic%2C AMPA1 (alpha 1) [Source:MGI Symbol;Acc:MGI:95808] Location: 11:56902213-57221070 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell neuron Other: Transmission across Chemical Synapses Membrane Trafficking Post-translational protein modification Hif1a Gene Information Basic Information Ensembl ID: ENSMUSG00000021109 Description: hypoxia inducible factor 1%2C alpha subunit [Source:MGI Symbol;Acc:MGI:106918] Location: 12:73948149-73994304 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell Regulatory T cell epithelial cell retinal pigment epithelial cell dendritic cell Other: Cellular responses to stress Post-translational protein modification Signaling by Non-Receptor Tyrosine Kinases Igfbp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000017493 Description: insulin-like growth factor binding protein 4 [Source:MGI Symbol;Acc:MGI:96439] Location: 11:98932070-98945218 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell stromal cell stem cell CD4+ T cell bone cell Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Lmo7 Gene Information Basic Information Ensembl ID: ENSMUSG00000033060 Description: LIM domain only 7 [Source:MGI Symbol;Acc:MGI:1353586] Location: 14:101967386-102172146 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell cardiomyocyte pneumocyte Other: Adaptive Immune System Post-translational protein modification Ltbp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001870 Description: latent transforming growth factor beta binding protein 1 [Source:MGI Symbol;Acc:MGI:109151] Location: 17:75312563-75699507 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Elastic fibre formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Lypd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026344 Description: Ly6/Plaur domain containing 1 [Source:MGI Symbol;Acc:MGI:1919835] Location: 1:125795359-125840838 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Post-translational protein modification Man1a Gene Information Basic Information Ensembl ID: ENSMUSG00000003746 Description: mannosidase 1%2C alpha [Source:MGI Symbol;Acc:MGI:104677] Location: 10:53780881-53952705 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Naive B cell fibroblast mesenchymal cell plasma cell Other: Post-translational protein modification Mdga1 Gene Information Basic Information Ensembl ID: ENSMUSG00000043557 Description: MAM domain containing glycosylphosphatidylinositol anchor 1 [Source:MGI Symbol;Acc:MGI:1922012] Location: 17:30046923-30189061 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Post-translational protein modification Ntm Gene Information Basic Information Ensembl ID: ENSMUSG00000059974 Description: neurotrimin [Source:MGI Symbol;Acc:MGI:2446259] Location: 9:28906046-29874437 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron pericyte sensory neuron sinoatrial node cell Other: Post-translational protein modification Penk Gene Information Basic Information Ensembl ID: ENSMUSG00000045573 Description: preproenkephalin [Source:MGI Symbol;Acc:MGI:104629] Location: 4:4133531-4138819 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell epithelial cell Other: Signaling by GPCR Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Prkn Gene Information Basic Information Ensembl ID: ENSMUSG00000023826 Description: parkin RBR E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1355296] Location: 17:11059271-12282248 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Regulated Necrosis Psmb8 Gene Information Basic Information Ensembl ID: ENSMUSG00000024338 Description: proteasome (prosome%2C macropain) subunit%2C beta type 8 (large multifunctional peptidase 7) [Source:MGI Symbol;Acc:MGI:1346527] Location: 17:34416695-34420428 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell dendritic cell developing T cell Regulatory T cell Naive B cell monocyte endothelial cell CD8+ T cell macrophage lymphocyte T cell Other: Adaptive Immune System Post-translational protein modification Pten Gene Information Basic Information Ensembl ID: ENSMUSG00000013663 Description: phosphatase and tensin homolog [Source:MGI Symbol;Acc:MGI:109583] Location: 19:32734897-32803560 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Inositol phosphate metabolism Metabolism of lipids Rab3a Gene Information Basic Information Ensembl ID: ENSMUSG00000031840 Description: RAB3A%2C member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97843] Location: 8:71207328-71211323 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Innate Immune System Membrane Trafficking Rab3b Gene Information Basic Information Ensembl ID: ENSMUSG00000003411 Description: RAB3B%2C member RAS oncogene family [Source:MGI Symbol;Acc:MGI:1917158] Location: 4:108736260-108800521 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron epithelial cell Other: Post-translational protein modification Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress Satb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000038331 Description: special AT-rich sequence binding protein 2 [Source:MGI Symbol;Acc:MGI:2679336] Location: 1:56833140-57017809 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: ectodermal cell osteoblast excitatory neuron Other: Post-translational protein modification Sema5a Gene Information Basic Information Ensembl ID: ENSMUSG00000022231 Description: sema domain%2C seven thrombospondin repeats (type 1 and type 1-like)%2C transmembrane domain (TM) and short cytoplasmic domain%2C (semaphorin) 5A [Source:MGI Symbol;Acc:MGI:107556] Location: 15:32244956-32696487 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell fibroblast neuron Other: Post-translational protein modification Nervous system development Spon1 Gene Information Basic Information Ensembl ID: ENSMUSG00000038156 Description: spondin 1%2C (f-spondin) extracellular matrix protein [Source:MGI Symbol;Acc:MGI:2385287] Location: 7:113365235-113642605 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast pericyte glial cell oligodendrocyte precursor cell Other: Post-translational protein modification Spp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029304 Description: secreted phosphoprotein 1 [Source:MGI Symbol;Acc:MGI:98389] Location: 5:104582984-104588916 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte glial cell epithelial cell fibroblast hepatocyte Other: Signaling by Receptor Tyrosine Kinases Degradation of the extracellular matrix Integrin cell surface interactions St3gal1 Gene Information Basic Information Ensembl ID: ENSMUSG00000013846 Description: ST3 beta-galactoside alpha-2%2C3-sialyltransferase 1 [Source:MGI Symbol;Acc:MGI:98304] Location: 15:66974724-67048679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Post-translational protein modification Metabolism of carbohydrates and carbohydrate derivatives St6galnac5 Gene Information Basic Information Ensembl ID: ENSMUSG00000039037 Description: ST6 (alpha-N-acetyl-neuraminyl-2%2C3-beta-galactosyl-1%2C3)-N-acetylgalactosaminide alpha-2%2C6-sialyltransferase 5 [Source:MGI Symbol;Acc:MGI:1349471] Location: 3:152522718-152687883 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron motor neuron adipocyte Other: Metabolism of lipids Post-translational protein modification Thrb Gene Information Basic Information Ensembl ID: ENSMUSG00000021779 Description: thyroid hormone receptor beta [Source:MGI Symbol;Acc:MGI:98743] Location: 14:4431611-4809435 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell skeletal muscle cell photoreceptor cell adipocyte Other: RNA Polymerase II Transcription Post-translational protein modification Tnc Gene Information Basic Information Ensembl ID: ENSMUSG00000028364 Description: tenascin C [Source:MGI Symbol;Acc:MGI:101922] Location: 4:63878022-63965252 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell fibroblast epithelial cell glial cell smooth muscle cell Other: Integrin cell surface interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Tnip1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020400 Description: TNFAIP3 interacting protein 1 [Source:MGI Symbol;Acc:MGI:1926194] Location: 11:54801611-54853743 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Post-translational protein modification Top2a Gene Information Basic Information Ensembl ID: ENSMUSG00000020914 Description: topoisomerase (DNA) II alpha [Source:MGI Symbol;Acc:MGI:98790] Location: 11:98883769-98915015 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stromal cell neuron T cell endothelial cell progenitor cell proliferative cell Other: Post-translational protein modification Vcan Gene Information Basic Information Ensembl ID: ENSMUSG00000021614 Description: versican [Source:MGI Symbol;Acc:MGI:102889] Location: 13:89803431-89890628 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast glial cell oligodendrocyte precursor cell epithelial cell monocyte pericyte mural cell Other: ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Wfs1 Gene Information Basic Information Ensembl ID: ENSMUSG00000039474 Description: wolframin ER transmembrane glycoprotein [Source:MGI Symbol;Acc:MGI:1328355] Location: 5:37123448-37146549 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification
Potassium Channels Pathway Hierarchies & Genes Activation of G protein gated Potassium channels (7 genes) Neuronal System Potassium Channels Inwardly rectifying K+ channels G protein gated Potassium channels Activation of G protein gated Potassium channels 7 genes ATP sensitive Potassium channels (2 genes) Neuronal System Potassium Channels Inwardly rectifying K+ channels ATP sensitive Potassium channels 2 genes TWIK-releated acid-sensitive K+ channel (TASK) (1 genes) Neuronal System Potassium Channels Tandem pore domain potassium channels TWIK-releated acid-sensitive K+ channel (TASK) 1 genes Ca2+ activated K+ channels (2 genes) Neuronal System Potassium Channels Ca2+ activated K+ channels 2 genes HCN channels (1 genes) Neuronal System Potassium Channels HCN channels 1 genes Voltage gated Potassium channels (11 genes) Neuronal System Potassium Channels Voltage gated Potassium channels 11 genes	Abcc9 Gene Information Basic Information Ensembl ID: ENSMUSG00000030249 Description: ATP-binding cassette%2C sub-family C member 9 [Source:MGI Symbol;Acc:MGI:1352630] Location: 6:142533588-142648041 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell pericyte Other: Potassium Channels ABC-family proteins mediated transport Cardiac conduction Gabbr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000039809 Description: gamma-aminobutyric acid type B receptor subunit 2 [Source:MGI Symbol;Acc:MGI:2386030] Location: 4:46662305-46991873 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron sensory neuron Other: Transmission across Chemical Synapses Potassium Channels Signaling by GPCR Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Hcn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000021730 Description: hyperpolarization activated cyclic nucleotide gated potassium channel 1 [Source:MGI Symbol;Acc:MGI:1096392] Location: 13:117738856-118123954 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron interneuron photoreceptor cell Other: Potassium Channels Kcna3 Gene Information Basic Information Ensembl ID: ENSMUSG00000047959 Description: potassium voltage-gated channel%2C shaker-related subfamily%2C member 3 [Source:MGI Symbol;Acc:MGI:96660] Location: 3:106943485-106945386 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Kcnab3 Gene Information Basic Information Ensembl ID: ENSMUSG00000018470 Description: potassium voltage-gated channel%2C shaker-related subfamily%2C beta member 3 [Source:MGI Symbol;Acc:MGI:1336208] Location: 11:69217084-69223868 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Kcnc1 Gene Information Basic Information Ensembl ID: ENSMUSG00000058975 Description: potassium voltage gated channel%2C Shaw-related subfamily%2C member 1 [Source:MGI Symbol;Acc:MGI:96667] Location: 7:46045921-46088128 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron Other: Potassium Channels Kcnc2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035681 Description: potassium voltage gated channel%2C Shaw-related subfamily%2C member 2 [Source:MGI Symbol;Acc:MGI:96668] Location: 10:112107026-112302929 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron neuron epithelial cell Other: Potassium Channels Integration of energy metabolism Kcnf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000051726 Description: potassium voltage-gated channel%2C subfamily F%2C member 1 [Source:MGI Symbol;Acc:MGI:2687399] Location: 12:17222101-17226889 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Kcng1 Gene Information Basic Information Ensembl ID: ENSMUSG00000074575 Description: potassium voltage-gated channel%2C subfamily G%2C member 1 [Source:MGI Symbol;Acc:MGI:3616086] Location: 2:168102037-168123656 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Kcng2 Gene Information Basic Information Ensembl ID: ENSMUSG00000059852 Description: potassium voltage-gated channel%2C subfamily G%2C member 2 [Source:MGI Symbol;Acc:MGI:3694646] Location: 18:80337761-80407469 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Potassium Channels Integration of energy metabolism Kcnh3 Gene Information Basic Information Ensembl ID: ENSMUSG00000037579 Description: potassium voltage-gated channel%2C subfamily H (eag-related)%2C member 3 [Source:MGI Symbol;Acc:MGI:1341723] Location: 15:99122742-99140698 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Kcnh8 Gene Information Basic Information Ensembl ID: ENSMUSG00000035580 Description: potassium voltage-gated channel%2C subfamily H (eag-related)%2C member 8 [Source:MGI Symbol;Acc:MGI:2445160] Location: 17:52909737-53286222 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: sensory neuron glial cell Other: Potassium Channels Kcnj10 Gene Information Basic Information Ensembl ID: ENSMUSG00000044708 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 10 [Source:MGI Symbol;Acc:MGI:1194504] Location: 1:172168777-172201652 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell glial cell Other: Transmission across Chemical Synapses Potassium Channels Kcnj2 Gene Information Basic Information Ensembl ID: ENSMUSG00000041695 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 2 [Source:MGI Symbol;Acc:MGI:104744] Location: 11:110956990-110967647 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Potassium Channels Cardiac conduction Kcnj3 Gene Information Basic Information Ensembl ID: ENSMUSG00000026824 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 3 [Source:MGI Symbol;Acc:MGI:104742] Location: 2:55325982-55488157 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell neuron cardiomyocyte retina cell Other: Transmission across Chemical Synapses Potassium Channels Kcnj4 Gene Information Basic Information Ensembl ID: ENSMUSG00000044216 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 4 [Source:MGI Symbol;Acc:MGI:104743] Location: 15:79367915-79389442 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Potassium Channels Cardiac conduction Kcnj5 Gene Information Basic Information Ensembl ID: ENSMUSG00000032034 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 5 [Source:MGI Symbol;Acc:MGI:104755] Location: 9:32226003-32255646 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Potassium Channels Kcnj8 Gene Information Basic Information Ensembl ID: ENSMUSG00000030247 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 8 [Source:MGI Symbol;Acc:MGI:1100508] Location: 6:142510563-142517340 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte Other: Potassium Channels Kcnk9 Gene Information Basic Information Ensembl ID: ENSMUSG00000036760 Description: potassium channel%2C subfamily K%2C member 9 [Source:MGI Symbol;Acc:MGI:3521816] Location: 15:72372938-72418189 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Cardiac conduction Kcnmb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000037610 Description: potassium large conductance calcium-activated channel%2C subfamily M%2C beta member 2 [Source:MGI Symbol;Acc:MGI:1919663] Location: 3:31956656-32254329 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron sensory neuron bipolar cell Other: Potassium Channels Kcnn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000002908 Description: potassium intermediate/small conductance calcium-activated channel%2C subfamily N%2C member 1 [Source:MGI Symbol;Acc:MGI:1933993] Location: 8:71294693-71315902 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Kcnq5 Gene Information Basic Information Ensembl ID: ENSMUSG00000028033 Description: potassium voltage-gated channel%2C subfamily Q%2C member 5 [Source:MGI Symbol;Acc:MGI:1924937] Location: 1:21468627-22032166 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell pericyte neuron epithelial cell astrocyte Other: Potassium Channels Kcns3 Gene Information Basic Information Ensembl ID: ENSMUSG00000043673 Description: potassium voltage-gated channel%2C delayed-rectifier%2C subfamily S%2C member 3 [Source:MGI Symbol;Acc:MGI:1098804] Location: 12:11140203-11201057 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Potassium Channels Integration of energy metabolism
Processing of Capped Intron-Containing Pre-mRNA Pathway Hierarchies & Genes Transport of the SLBP independent Mature mRNA (1 genes) Metabolism of RNA Processing of Capped Intron-Containing Pre-mRNA Transport of Mature Transcript to Cytoplasm Transport of Mature mRNAs Derived from Intronless Transcripts Transport of the SLBP independent Mature mRNA 1 genes mRNA Splicing - Major Pathway (1 genes) Metabolism of RNA Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway 1 genes	Fus Gene Information Basic Information Ensembl ID: ENSMUSG00000030795 Description: fused in sarcoma [Source:MGI Symbol;Acc:MGI:1353633] Location: 7:127566629-127584873 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Processing of Capped Intron-Containing Pre-mRNA Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress
Protein folding Pathway Hierarchies & Genes Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (4 genes) Metabolism of proteins Protein folding Chaperonin-mediated protein folding Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding 4 genes	Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Rgs6 Gene Information Basic Information Ensembl ID: ENSMUSG00000021219 Description: regulator of G-protein signaling 6 [Source:MGI Symbol;Acc:MGI:1354730] Location: 12:82635066-83208830 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell intercalated cell smooth muscle cell glial cell excitatory neuron Other: Signaling by GPCR Protein folding Rgs7 Gene Information Basic Information Ensembl ID: ENSMUSG00000026527 Description: regulator of G protein signaling 7 [Source:MGI Symbol;Acc:MGI:1346089] Location: 1:174886653-175320066 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron motor neuron adipocyte Other: Signaling by GPCR Protein folding Rgs9 Gene Information Basic Information Ensembl ID: ENSMUSG00000020599 Description: regulator of G-protein signaling 9 [Source:MGI Symbol;Acc:MGI:1338824] Location: 11:109116181-109188955 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell photoreceptor cell projection neuron Other: Visual phototransduction Signaling by GPCR Protein folding
Protein-protein interactions at synapses Pathway Hierarchies & Genes Synaptic adhesion-like molecules (6 genes) Neuronal System Protein-protein interactions at synapses Neurexins and neuroligins 5 genes Synaptic adhesion-like molecules 1 genes Receptor-type tyrosine-protein phosphatases (5 genes) Neuronal System Protein-protein interactions at synapses Receptor-type tyrosine-protein phosphatases 5 genes Synaptic adhesion-like molecules (6 genes) Neuronal System Protein-protein interactions at synapses Synaptic adhesion-like molecules 6 genes	Dlg4 Gene Information Basic Information Ensembl ID: ENSMUSG00000020886 Description: discs large MAGUK scaffold protein 4 [Source:MGI Symbol;Acc:MGI:1277959] Location: 11:69907768-69938348 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Transmission across Chemical Synapses LGI-ADAM interactions MAPK family signaling cascades Dlgap2 Gene Information Basic Information Ensembl ID: ENSMUSG00000047495 Description: DLG associated protein 2 [Source:MGI Symbol;Acc:MGI:2443181] Location: 8:14145865-14897680 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron interneuron Other: Protein-protein interactions at synapses Gria1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020524 Description: glutamate receptor%2C ionotropic%2C AMPA1 (alpha 1) [Source:MGI Symbol;Acc:MGI:95808] Location: 11:56902213-57221070 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell neuron Other: Transmission across Chemical Synapses Membrane Trafficking Post-translational protein modification Gria3 Gene Information Basic Information Ensembl ID: ENSMUSG00000001986 Description: glutamate receptor%2C ionotropic%2C AMPA3 (alpha 3) [Source:MGI Symbol;Acc:MGI:95810] Location: X:40489731-40767478 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell epithelial cell inhibitory neuron projection neuron Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Gria4 Gene Information Basic Information Ensembl ID: ENSMUSG00000025892 Description: glutamate receptor%2C ionotropic%2C AMPA4 (alpha 4) [Source:MGI Symbol;Acc:MGI:95811] Location: 9:4417896-4796234 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell neuron interneuron Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Grin1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026959 Description: glutamate receptor%2C ionotropic%2C NMDA1 (zeta 1) [Source:MGI Symbol;Acc:MGI:95819] Location: 2:25181193-25209199 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses MAPK family signaling cascades Protein-protein interactions at synapses Grin2a Gene Information Basic Information Ensembl ID: ENSMUSG00000059003 Description: glutamate receptor%2C ionotropic%2C NMDA2A (epsilon 1) [Source:MGI Symbol;Acc:MGI:95820] Location: 16:9385762-9813424 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Grin2c Gene Information Basic Information Ensembl ID: ENSMUSG00000020734 Description: glutamate receptor%2C ionotropic%2C NMDA2C (epsilon 3) [Source:MGI Symbol;Acc:MGI:95822] Location: 11:115139995-115158069 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Grm1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019828 Description: glutamate receptor%2C metabotropic 1 [Source:MGI Symbol;Acc:MGI:1351338] Location: 10:10561803-10958100 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron interneuron cajal-retzius cell Other: Signaling by GPCR Protein-protein interactions at synapses Grm5 Gene Information Basic Information Ensembl ID: ENSMUSG00000049583 Description: glutamate receptor%2C metabotropic 5 [Source:MGI Symbol;Acc:MGI:1351342] Location: 7:87233376-87784115 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Signaling by GPCR Protein-protein interactions at synapses Homer1 Gene Information Basic Information Ensembl ID: ENSMUSG00000007617 Description: homer scaffolding protein 1 [Source:MGI Symbol;Acc:MGI:1347345] Location: 13:93436143-93541637 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Protein-protein interactions at synapses Homer3 Gene Information Basic Information Ensembl ID: ENSMUSG00000003573 Description: homer scaffolding protein 3 [Source:MGI Symbol;Acc:MGI:1347359] Location: 8:70735477-70747011 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Protein-protein interactions at synapses Il1rap Gene Information Basic Information Ensembl ID: ENSMUSG00000022514 Description: interleukin 1 receptor accessory protein [Source:MGI Symbol;Acc:MGI:104975] Location: 16:26400454-26548867 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell bipolar cell neuron Other: Cytokine Signaling in Immune system Protein-protein interactions at synapses Intracellular signaling by second messengers Il1rapl2 Gene Information Basic Information Ensembl ID: ENSMUSG00000059203 Description: interleukin 1 receptor accessory protein-like 2 [Source:MGI Symbol;Acc:MGI:1913106] Location: X:136471357-137747695 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Protein-protein interactions at synapses Ntrk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000059146 Description: neurotrophic tyrosine kinase%2C receptor%2C type 3 [Source:MGI Symbol;Acc:MGI:97385] Location: 7:77825707-78387760 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Protein-protein interactions at synapses Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Ppfia2 Gene Information Basic Information Ensembl ID: ENSMUSG00000053825 Description: protein tyrosine phosphatase%2C receptor type%2C f polypeptide (PTPRF)%2C interacting protein (liprin)%2C alpha 2 [Source:MGI Symbol;Acc:MGI:2443834] Location: 10:106306200-106771813 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron pericyte Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Ppfia4 Gene Information Basic Information Ensembl ID: ENSMUSG00000026458 Description: protein tyrosine phosphatase%2C receptor type%2C f polypeptide (PTPRF)%2C interacting protein (liprin)%2C alpha 4 [Source:MGI Symbol;Acc:MGI:1915757] Location: 1:134224521-134260666 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Protein-protein interactions at synapses
RNA Polymerase I Transcription Pathway Hierarchies & Genes RNA Polymerase I Promoter Opening (1 genes) Gene expression (Transcription) RNA Polymerase I Transcription RNA Polymerase I Promoter Clearance RNA Polymerase I Promoter Opening 1 genes	Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system
RNA Polymerase II Transcription Pathway Hierarchies & Genes Regulation of TP53 Degradation (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional Regulation by TP53 Regulation of TP53 Activity Regulation of TP53 Expression and Degradation Regulation of TP53 Degradation 1 genes Regulation of TP53 Activity through Association with Co-factors (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional Regulation by TP53 Regulation of TP53 Activity Regulation of TP53 Activity through Association with Co-factors 1 genes Regulation of TP53 Activity through Phosphorylation (2 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional Regulation by TP53 Regulation of TP53 Activity Regulation of TP53 Activity through Phosphorylation 2 genes TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional Regulation by TP53 TP53 Regulates Transcription of Cell Cycle Genes TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest 1 genes TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional Regulation by TP53 TP53 Regulates Transcription of Cell Cycle Genes TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain 1 genes Negative regulation of activity of TFAP2 (AP-2) family transcription factors (2 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors 2 genes RUNX1 regulates transcription of genes involved in BCR signaling (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional regulation by RUNX1 RUNX1 regulates transcription of genes involved in BCR signaling 1 genes RUNX1 regulates transcription of genes involved in differentiation of HSCs (4 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional regulation by RUNX1 RUNX1 regulates transcription of genes involved in differentiation of HSCs 4 genes RUNX3 regulates CDKN1A transcription (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional regulation by RUNX3 RUNX3 regulates CDKN1A transcription 1 genes RUNX3 regulates NOTCH signaling (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional regulation by RUNX3 RUNX3 regulates NOTCH signaling 1 genes RUNX3 regulates WNT signaling (3 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional regulation by RUNX3 RUNX3 regulates WNT signaling 3 genes Regulation of MECP2 expression and activity (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional Regulation by MECP2 Regulation of MECP2 expression and activity 1 genes Regulation of RUNX1 Expression and Activity (3 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional regulation by RUNX1 Regulation of RUNX1 Expression and Activity 3 genes Regulation of localization of FOXO transcription factors (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway FOXO-mediated transcription Regulation of localization of FOXO transcription factors 1 genes TP53 Regulates Metabolic Genes (2 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional Regulation by TP53 TP53 Regulates Metabolic Genes 2 genes Nuclear Receptor transcription pathway (6 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Nuclear Receptor transcription pathway 6 genes Transcriptional regulation by RUNX2 (1 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway Transcriptional regulation by RUNX2 1 genes Generic Transcription Pathway (4 genes) Gene expression (Transcription) RNA Polymerase II Transcription Generic Transcription Pathway 4 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Ccnd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000070348 Description: cyclin D1 [Source:MGI Symbol;Acc:MGI:88313] Location: 7:144483668-144493662 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte endothelial cell glial cell dendritic cell epithelial cell Other: Chromatin modifying enzymes Cell Cycle, Mitotic RNA Polymerase II Transcription Ccnd2 Gene Information Basic Information Ensembl ID: ENSMUSG00000000184 Description: cyclin D2 [Source:MGI Symbol;Acc:MGI:88314] Location: 6:127102125-127129156 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell developing T cell hematopoietic stem cell endothelial cell stem cell smooth muscle cell fibroblast CD4+ T cell pancreatic cell goblet cell mural cell Other: Cell Cycle, Mitotic RNA Polymerase II Transcription Cdkn1a Gene Information Basic Information Ensembl ID: ENSMUSG00000023067 Description: cyclin dependent kinase inhibitor 1A [Source:MGI Symbol;Acc:MGI:104556] Location: 17:29309950-29319701 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast muscle cell smooth muscle cell schwann cell monocyte epithelial cell Other: Cellular responses to stress Cell Cycle, Mitotic Cell Cycle Checkpoints Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Foxo1 Gene Information Basic Information Ensembl ID: ENSMUSG00000044167 Description: forkhead box O1 [Source:MGI Symbol;Acc:MGI:1890077] Location: 3:52175757-52260642 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell epithelial cell Other: Regulation of beta-cell development MAPK family signaling cascades RNA Polymerase II Transcription Gata3 Gene Information Basic Information Ensembl ID: ENSMUSG00000015619 Description: GATA binding protein 3 [Source:MGI Symbol;Acc:MGI:95663] Location: 2:9861889-9894845 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell epithelial cell stem cell CD4+ T cell innate lymphoid cell developing T cell mesangial cell Other: Post-translational protein modification RNA Polymerase II Transcription Signaling by Nuclear Receptors Gls Gene Information Basic Information Ensembl ID: ENSMUSG00000026103 Description: glutaminase [Source:MGI Symbol;Acc:MGI:95752] Location: 1:52202607-52272391 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Metabolism of amino acids and derivatives RNA Polymerase II Transcription Gls2 Gene Information Basic Information Ensembl ID: ENSMUSG00000044005 Description: glutaminase 2 (liver%2C mitochondrial) [Source:MGI Symbol;Acc:MGI:2143539] Location: 10:128030326-128045873 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Metabolism of amino acids and derivatives RNA Polymerase II Transcription Itch Gene Information Basic Information Ensembl ID: ENSMUSG00000027598 Description: itchy%2C E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1202301] Location: 2:154975429-155068775 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Signaling by NOTCH Innate Immune System Lef1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027985 Description: lymphoid enhancer binding factor 1 [Source:MGI Symbol;Acc:MGI:96770] Location: 3:130904120-131018005 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell developing T cell lymphoid progenitor cell Specialized T cell melanocyte CD8+ T cell memory T cell Other: Signaling by WNT RNA Polymerase II Transcription MITF-M-regulated melanocyte development Lmo1 Gene Information Basic Information Ensembl ID: ENSMUSG00000036111 Description: LIM domain only 1 [Source:MGI Symbol;Acc:MGI:102812] Location: 7:108737779-108774414 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stem cell epithelial cell retina cell Other: RNA Polymerase II Transcription Maml2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031925 Description: mastermind like transcriptional coactivator 2 [Source:MGI Symbol;Acc:MGI:2389460] Location: 9:13298306-13620684 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte oligodendrocyte precursor cell epithelial cell astrocyte mesenchymal cell Other: Signaling by NOTCH RNA Polymerase II Transcription Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mecp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031393 Description: methyl CpG binding protein 2 [Source:MGI Symbol;Acc:MGI:99918] Location: X:73070198-73129296 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: RNA Polymerase II Transcription Nedd4l Gene Information Basic Information Ensembl ID: ENSMUSG00000024589 Description: neural precursor cell expressed%2C developmentally down-regulated gene 4-like [Source:MGI Symbol;Acc:MGI:1933754] Location: 18:65020776-65350899 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Adaptive Immune System RNA Polymerase II Transcription Signaling by TGFB family members Nr2f1 Gene Information Basic Information Ensembl ID: ENSMUSG00000069171 Description: nuclear receptor subfamily 2%2C group F%2C member 1 [Source:MGI Symbol;Acc:MGI:1352451] Location: 13:78337092-78347876 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte progenitor cell glial cell schwann cell Other: RNA Polymerase II Transcription Nr4a2 Gene Information Basic Information Ensembl ID: ENSMUSG00000026826 Description: nuclear receptor subfamily 4%2C group A%2C member 2 [Source:MGI Symbol;Acc:MGI:1352456] Location: 2:56996842-57014015 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell dendritic cell schwann cell Other: RNA Polymerase II Transcription Nr4a3 Gene Information Basic Information Ensembl ID: ENSMUSG00000028341 Description: nuclear receptor subfamily 4%2C group A%2C member 3 [Source:MGI Symbol;Acc:MGI:1352457] Location: 4:48045153-48086447 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell mural cell Other: RNA Polymerase II Transcription Pax5 Gene Information Basic Information Ensembl ID: ENSMUSG00000014030 Description: paired box 5 [Source:MGI Symbol;Acc:MGI:97489] Location: 4:44524757-44710487 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell Other: RNA Polymerase II Transcription Plk2 Gene Information Basic Information Ensembl ID: ENSMUSG00000021701 Description: polo like kinase 2 [Source:MGI Symbol;Acc:MGI:1099790] Location: 13:110531580-110537378 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell tuft cell Other: RNA Polymerase II Transcription Pou4f1 Gene Information Basic Information Ensembl ID: ENSMUSG00000048349 Description: POU domain%2C class 4%2C transcription factor 1 [Source:MGI Symbol;Acc:MGI:102525] Location: 14:104699112-104705435 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron sensory neuron ganglion Other: RNA Polymerase II Transcription Prkaa2 Gene Information Basic Information Ensembl ID: ENSMUSG00000028518 Description: protein kinase%2C AMP-activated%2C alpha 2 catalytic subunit [Source:MGI Symbol;Acc:MGI:1336173] Location: 4:104887071-104967087 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte Other: Macroautophagy Integration of energy metabolism MTOR signalling Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Rorb Gene Information Basic Information Ensembl ID: ENSMUSG00000036192 Description: RAR-related orphan receptor beta [Source:MGI Symbol;Acc:MGI:1343464] Location: 19:18907969-19088560 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell neuron Other: RNA Polymerase II Transcription Rxrg Gene Information Basic Information Ensembl ID: ENSMUSG00000015843 Description: retinoid X receptor gamma [Source:MGI Symbol;Acc:MGI:98216] Location: 1:167425953-167467192 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron photoreceptor cell inhibitory neuron Other: RNA Polymerase II Transcription Signaling by Nuclear Receptors Skil Gene Information Basic Information Ensembl ID: ENSMUSG00000027660 Description: SKI-like [Source:MGI Symbol;Acc:MGI:106203] Location: 3:31149207-31176726 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: RNA Polymerase II Transcription Signaling by TGFB family members Sox9 Gene Information Basic Information Ensembl ID: ENSMUSG00000000567 Description: SRY (sex determining region Y)-box 9 [Source:MGI Symbol;Acc:MGI:98371] Location: 11:112673050-112678586 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stromal cell tuft cell muscle cell chondrocyte bone cell progenitor cell hepatocyte natural killer cell stem cell Other: Signaling by WNT RNA Polymerase II Transcription Tal1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028717 Description: T cell acute lymphocytic leukemia 1 [Source:MGI Symbol;Acc:MGI:98480] Location: 4:114913623-114928952 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: hematopoietic progenitor cell Other: RNA Polymerase II Transcription Tcf7l2 Gene Information Basic Information Ensembl ID: ENSMUSG00000024985 Description: transcription factor 7 like 2%2C T cell specific%2C HMG box [Source:MGI Symbol;Acc:MGI:1202879] Location: 19:55730252-55922086 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell fibroblast macrophage excitatory neuron mesenchymal cell oligodendrocyte Other: Signaling by WNT RNA Polymerase II Transcription MITF-M-regulated melanocyte development Tfap2b Gene Information Basic Information Ensembl ID: ENSMUSG00000025927 Description: transcription factor AP-2 beta [Source:MGI Symbol;Acc:MGI:104672] Location: 1:19279138-19308800 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stem cell interneuron progenitor cell Other: RNA Polymerase II Transcription Gastrulation Tfap2d Gene Information Basic Information Ensembl ID: ENSMUSG00000042596 Description: transcription factor AP-2%2C delta [Source:MGI Symbol;Acc:MGI:2153466] Location: 1:19173246-19236570 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: RNA Polymerase II Transcription Tgfb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000002603 Description: transforming growth factor%2C beta 1 [Source:MGI Symbol;Acc:MGI:98725] Location: 7:25386427-25404502 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell hematopoietic stem cell phagocyte monocyte leukocyte megakaryocyte Other: Cell surface interactions at the vascular wall Non-integrin membrane-ECM interactions Elastic fibre formation Thrb Gene Information Basic Information Ensembl ID: ENSMUSG00000021779 Description: thyroid hormone receptor beta [Source:MGI Symbol;Acc:MGI:98743] Location: 14:4431611-4809435 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell skeletal muscle cell photoreceptor cell adipocyte Other: RNA Polymerase II Transcription Post-translational protein modification
Regulated Necrosis Pathway Hierarchies & Genes Regulation of necroptotic cell death (2 genes) Programmed Cell Death Regulated Necrosis RIPK1-mediated regulated necrosis Regulation of necroptotic cell death 2 genes Pyroptosis (1 genes) Programmed Cell Death Regulated Necrosis Pyroptosis 1 genes	Il1b Gene Information Basic Information Ensembl ID: ENSMUSG00000027398 Description: interleukin 1 beta [Source:MGI Symbol;Acc:MGI:96543] Location: 2:129206490-129213059 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell dendritic cell phagocyte granulocyte myeloid cell erythroid lineage cell T cell leukocyte macrophage Other: Cytokine Signaling in Immune system Innate Immune System Regulated Necrosis Itch Gene Information Basic Information Ensembl ID: ENSMUSG00000027598 Description: itchy%2C E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1202301] Location: 2:154975429-155068775 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Signaling by NOTCH Innate Immune System Prkn Gene Information Basic Information Ensembl ID: ENSMUSG00000023826 Description: parkin RBR E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1355296] Location: 17:11059271-12282248 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Regulated Necrosis
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Pathway Hierarchies & Genes Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) (17 genes) Metabolism of proteins Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) 17 genes	Bmp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000021835 Description: bone morphogenetic protein 4 [Source:MGI Symbol;Acc:MGI:88180] Location: 14:46620977-46628126 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stem cell fibroblast epithelial cell smooth muscle cell ectodermal cell endothelial cell mesodermal cell Other: Elastic fibre formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification C3 Gene Information Basic Information Ensembl ID: ENSMUSG00000024164 Description: complement component 3 [Source:MGI Symbol;Acc:MGI:88227] Location: 17:57510970-57535136 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell fibroblast stellate cell stem cell endothelial cell stromal cell epithelial cell hepatocyte Other: Adaptive Immune System Innate Immune System Signaling by GPCR Csf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000014599 Description: colony stimulating factor 1 (macrophage) [Source:MGI Symbol;Acc:MGI:1339753] Location: 3:107648364-107667785 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell basophil eosinophil Other: Cytokine Signaling in Immune system Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Gpc3 Gene Information Basic Information Ensembl ID: ENSMUSG00000055653 Description: glypican 3 [Source:MGI Symbol;Acc:MGI:104903] Location: X:51361303-51702827 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell stromal cell embryonic cell fibroblast epithelial cell Other: Metabolism of vitamins and cofactors Visual phototransduction Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Igf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020053 Description: insulin-like growth factor 1 [Source:MGI Symbol;Acc:MGI:96432] Location: 10:87694127-87772904 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell interneuron phagocyte smooth muscle cell epithelial cell stromal cell macrophage dendritic cell Other: Peptide hormone metabolism Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Platelet activation, signaling and aggregation Igf2 Gene Information Basic Information Ensembl ID: ENSMUSG00000048583 Description: insulin-like growth factor 2 [Source:MGI Symbol;Acc:MGI:96434] Location: 7:142204503-142220553 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stromal cell fibroblast endothelial cell mesothelial cell endocardial cell Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Platelet activation, signaling and aggregation Signaling by Receptor Tyrosine Kinases Igfbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000039323 Description: insulin-like growth factor binding protein 2 [Source:MGI Symbol;Acc:MGI:96437] Location: 1:72863662-72891633 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stem cell fibroblast basal cell pneumocyte astrocyte mesothelial cell Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Igfbp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000017493 Description: insulin-like growth factor binding protein 4 [Source:MGI Symbol;Acc:MGI:96439] Location: 11:98932070-98945218 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell stromal cell stem cell CD4+ T cell bone cell Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Igfbp6 Gene Information Basic Information Ensembl ID: ENSMUSG00000023046 Description: insulin-like growth factor binding protein 6 [Source:MGI Symbol;Acc:MGI:96441] Location: 15:102052797-102057946 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell stem cell stromal cell epithelial cell Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Ltbp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001870 Description: latent transforming growth factor beta binding protein 1 [Source:MGI Symbol;Acc:MGI:109151] Location: 17:75312563-75699507 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Elastic fibre formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Pappa Gene Information Basic Information Ensembl ID: ENSMUSG00000028370 Description: pregnancy-associated plasma protein A [Source:MGI Symbol;Acc:MGI:97479] Location: 4:65042411-65275746 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Penk Gene Information Basic Information Ensembl ID: ENSMUSG00000045573 Description: preproenkephalin [Source:MGI Symbol;Acc:MGI:104629] Location: 4:4133531-4138819 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell epithelial cell Other: Signaling by GPCR Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Spp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029304 Description: secreted phosphoprotein 1 [Source:MGI Symbol;Acc:MGI:98389] Location: 5:104582984-104588916 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte glial cell epithelial cell fibroblast hepatocyte Other: Signaling by Receptor Tyrosine Kinases Degradation of the extracellular matrix Integrin cell surface interactions Tnc Gene Information Basic Information Ensembl ID: ENSMUSG00000028364 Description: tenascin C [Source:MGI Symbol;Acc:MGI:101922] Location: 4:63878022-63965252 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell fibroblast epithelial cell glial cell smooth muscle cell Other: Integrin cell surface interactions ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Vcan Gene Information Basic Information Ensembl ID: ENSMUSG00000021614 Description: versican [Source:MGI Symbol;Acc:MGI:102889] Location: 13:89803431-89890628 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast glial cell oligodendrocyte precursor cell epithelial cell monocyte pericyte mural cell Other: ECM proteoglycans Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Wfs1 Gene Information Basic Information Ensembl ID: ENSMUSG00000039474 Description: wolframin ER transmembrane glycoprotein [Source:MGI Symbol;Acc:MGI:1328355] Location: 5:37123448-37146549 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification
Regulation of beta-cell development Pathway Hierarchies & Genes AKT-mediated inactivation of FOXO1A (2 genes) Developmental Biology Regulation of beta-cell development Regulation of gene expression in beta cells AKT-mediated inactivation of FOXO1A 2 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Foxo1 Gene Information Basic Information Ensembl ID: ENSMUSG00000044167 Description: forkhead box O1 [Source:MGI Symbol;Acc:MGI:1890077] Location: 3:52175757-52260642 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell epithelial cell Other: Regulation of beta-cell development MAPK family signaling cascades RNA Polymerase II Transcription
Regulation of mRNA stability by proteins that bind AU-rich elements Pathway Hierarchies & Genes KSRP (KHSRP) binds and destabilizes mRNA (1 genes) Metabolism of RNA Regulation of mRNA stability by proteins that bind AU-rich elements Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA KSRP (KHSRP) binds and destabilizes mRNA 1 genes HuR (ELAVL1) binds and stabilizes mRNA (1 genes) Metabolism of RNA Regulation of mRNA stability by proteins that bind AU-rich elements HuR (ELAVL1) binds and stabilizes mRNA 1 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system
Reversible hydration of carbon dioxide Pathway Hierarchies & Genes Reversible hydration of carbon dioxide (2 genes) Metabolism Reversible hydration of carbon dioxide 2 genes	Car14 Gene Information Basic Information Ensembl ID: ENSMUSG00000038526 Description: carbonic anhydrase 14 [Source:MGI Symbol;Acc:MGI:1344341] Location: 3:95805080-95812003 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell retinal pigment epithelial cell Other: Reversible hydration of carbon dioxide Car4 Gene Information Basic Information Ensembl ID: ENSMUSG00000000805 Description: carbonic anhydrase 4 [Source:MGI Symbol;Acc:MGI:1096574] Location: 11:84848612-84856870 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell epithelial cell smooth muscle cell eosinophil Other: Reversible hydration of carbon dioxide O2/CO2 exchange in erythrocytes
SLC-mediated transmembrane transport Pathway Hierarchies & Genes Amino acid transport across the plasma membrane (3 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of inorganic cations/anions and amino acids/oligopeptides Amino acid transport across the plasma membrane 3 genes Bicarbonate transporters (2 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of inorganic cations/anions and amino acids/oligopeptides Bicarbonate transporters 2 genes Inositol transporters (1 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of bile salts and organic acids, metal ions and amine compounds Inositol transporters 1 genes Na+/Cl- dependent neurotransmitter transporters (4 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of bile salts and organic acids, metal ions and amine compounds Na+/Cl- dependent neurotransmitter transporters 4 genes Organic anion transporters (4 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of inorganic cations/anions and amino acids/oligopeptides Organic anion transporters 4 genes Proton/oligopeptide cotransporters (1 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of inorganic cations/anions and amino acids/oligopeptides Proton/oligopeptide cotransporters 1 genes Transport of organic anions (1 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of vitamins, nucleosides, and related molecules Transport of organic anions 1 genes Cellular hexose transport (1 genes) Transport of small molecules SLC-mediated transmembrane transport Cellular hexose transport 1 genes Transport of bile salts and organic acids, metal ions and amine compounds (2 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of bile salts and organic acids, metal ions and amine compounds 2 genes Transport of inorganic cations/anions and amino acids/oligopeptides (1 genes) Transport of small molecules SLC-mediated transmembrane transport Transport of inorganic cations/anions and amino acids/oligopeptides 1 genes	Slc15a3 Gene Information Basic Information Ensembl ID: ENSMUSG00000024737 Description: solute carrier family 15%2C member 3 [Source:MGI Symbol;Acc:MGI:1929691] Location: 19:10817091-10836726 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell phagocyte macrophage myeloid cell Other: SLC-mediated transmembrane transport Slc17a6 Gene Information Basic Information Ensembl ID: ENSMUSG00000030500 Description: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter)%2C member 6 [Source:MGI Symbol;Acc:MGI:2156052] Location: 7:51271754-51320867 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell cajal-retzius cell neuron excitatory neuron Other: SLC-mediated transmembrane transport Slc17a7 Gene Information Basic Information Ensembl ID: ENSMUSG00000070570 Description: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter)%2C member 7 [Source:MGI Symbol;Acc:MGI:1920211] Location: 7:44813373-44825566 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron excitatory neuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc17a8 Gene Information Basic Information Ensembl ID: ENSMUSG00000019935 Description: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter)%2C member 8 [Source:MGI Symbol;Acc:MGI:3039629] Location: 10:89409882-89457115 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: SLC-mediated transmembrane transport Slc18a2 Gene Information Basic Information Ensembl ID: ENSMUSG00000025094 Description: solute carrier family 18 (vesicular monoamine)%2C member 2 [Source:MGI Symbol;Acc:MGI:106677] Location: 19:59249328-59284444 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mast cell modulatory neuron neuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc25a18 Gene Information Basic Information Ensembl ID: ENSMUSG00000004902 Description: solute carrier family 25 (mitochondrial carrier)%2C member 18 [Source:MGI Symbol;Acc:MGI:1919053] Location: 6:120750539-120771297 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Aerobic respiration and respiratory electron transport SLC-mediated transmembrane transport Slc2a13 Gene Information Basic Information Ensembl ID: ENSMUSG00000036298 Description: solute carrier family 2 (facilitated glucose transporter)%2C member 13 [Source:MGI Symbol;Acc:MGI:2146030] Location: 15:91151899-91457464 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell interneuron Other: SLC-mediated transmembrane transport Slc2a2 Gene Information Basic Information Ensembl ID: ENSMUSG00000027690 Description: solute carrier family 2 (facilitated glucose transporter)%2C member 2 [Source:MGI Symbol;Acc:MGI:1095438] Location: 3:28752052-28785508 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Integration of energy metabolism SLC-mediated transmembrane transport Intestinal absorption Slc32a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000037771 Description: solute carrier family 32 (GABA vesicular transporter)%2C member 1 [Source:MGI Symbol;Acc:MGI:1194488] Location: 2:158452687-158457668 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc38a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000023169 Description: solute carrier family 38%2C member 1 [Source:MGI Symbol;Acc:MGI:2145895] Location: 15:96469299-96540794 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell dendritic cell Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc44a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028412 Description: solute carrier family 44%2C member 1 [Source:MGI Symbol;Acc:MGI:2140592] Location: 4:53440413-53622478 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: SLC-mediated transmembrane transport Metabolism of lipids Metabolism of amino acids and derivatives Slc4a2 Gene Information Basic Information Ensembl ID: ENSMUSG00000028962 Description: solute carrier family 4 (anion exchanger)%2C member 2 [Source:MGI Symbol;Acc:MGI:109351] Location: 5:24628835-24645948 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: SLC-mediated transmembrane transport Slc4a4 Gene Information Basic Information Ensembl ID: ENSMUSG00000060961 Description: solute carrier family 4 (anion exchanger)%2C member 4 [Source:MGI Symbol;Acc:MGI:1927555] Location: 5:89034345-89387512 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell adipocyte epithelial cell fibroblast glial cell astrocyte Other: SLC-mediated transmembrane transport Slc5a7 Gene Information Basic Information Ensembl ID: ENSMUSG00000023945 Description: solute carrier family 5 (choline transporter)%2C member 7 [Source:MGI Symbol;Acc:MGI:1927126] Location: 17:54580618-54606062 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: motor neuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc6a11 Gene Information Basic Information Ensembl ID: ENSMUSG00000030307 Description: solute carrier family 6 (neurotransmitter transporter%2C GABA)%2C member 11 [Source:MGI Symbol;Acc:MGI:95630] Location: 6:114108202-114226913 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell astrocyte Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Metabolism of amino acids and derivatives Slc6a3 Gene Information Basic Information Ensembl ID: ENSMUSG00000021609 Description: solute carrier family 6 (neurotransmitter transporter%2C dopamine)%2C member 3 [Source:MGI Symbol;Acc:MGI:94862] Location: 13:73684866-73726791 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: modulatory neuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc6a5 Gene Information Basic Information Ensembl ID: ENSMUSG00000039728 Description: solute carrier family 6 (neurotransmitter transporter%2C glycine)%2C member 5 [Source:MGI Symbol;Acc:MGI:105090] Location: 7:49559894-49613604 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: SLC-mediated transmembrane transport Slc7a10 Gene Information Basic Information Ensembl ID: ENSMUSG00000030495 Description: solute carrier family 7 (cationic amino acid transporter%2C y+ system)%2C member 10 [Source:MGI Symbol;Acc:MGI:1858261] Location: 7:34885810-34900539 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell astrocyte adipocyte preadipocyte Other: Cell surface interactions at the vascular wall SLC-mediated transmembrane transport Slc7a11 Gene Information Basic Information Ensembl ID: ENSMUSG00000027737 Description: solute carrier family 7 (cationic amino acid transporter%2C y+ system)%2C member 11 [Source:MGI Symbol;Acc:MGI:1347355] Location: 3:49846975-50398063 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell fibroblast granulocyte monocyte retinal pigment epithelial cell Other: Cell surface interactions at the vascular wall SLC-mediated transmembrane transport Slco3a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025790 Description: solute carrier organic anion transporter family%2C member 3a1 [Source:MGI Symbol;Acc:MGI:1351867] Location: 7:73925167-74204528 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte hematopoietic stem cell epithelial cell Other: SLC-mediated transmembrane transport
Signal regulatory protein family interactions Pathway Hierarchies & Genes Signal regulatory protein family interactions (2 genes) Cell-Cell communication Signal regulatory protein family interactions 2 genes	Fyb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000022148 Description: FYN binding protein 1 [Source:MGI Symbol;Acc:MGI:1346327] Location: 15:6552334-6692794 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell Regulatory T cell phagocyte monocyte tuft cell dendritic cell myeloid progenitor cell Other: Adaptive Immune System Signal regulatory protein family interactions Ptk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000059456 Description: PTK2 protein tyrosine kinase 2 beta [Source:MGI Symbol;Acc:MGI:104908] Location: 14:66390706-66518501 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell Specialized T cell neuron Other: Cytokine Signaling in Immune system Signal regulatory protein family interactions Signaling by Receptor Tyrosine Kinases
Signaling by Erythropoietin Pathway Hierarchies & Genes Erythropoietin activates RAS (2 genes) Signal Transduction Signaling by Erythropoietin Erythropoietin activates Phosphoinositide-3-kinase (PI3K) 1 genes Erythropoietin activates RAS 1 genes	Irs2 Gene Information Basic Information Ensembl ID: ENSMUSG00000038894 Description: insulin receptor substrate 2 [Source:MGI Symbol;Acc:MGI:109334] Location: 8:11034681-11058458 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mural cell Other: Cytokine Signaling in Immune system MAPK family signaling cascades Signaling by Erythropoietin Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System
Signaling by GPCR Pathway Hierarchies & Genes Peptide ligand-binding receptors (4 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (i) signalling events Opioid Signalling G-protein activation GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Peptide ligand-binding receptors 4 genes phospho-PLA2 pathway (1 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (i) signalling events Opioid Signalling G-protein mediated events PLC beta mediated events Ca-dependent events phospho-PLA2 pathway 1 genes Ca-dependent events (7 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (i) signalling events Opioid Signalling G-protein mediated events PLC beta mediated events Ca-dependent events 7 genes G alpha (i) signalling events (4 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Nucleotide-like (purinergic) receptors Adenosine P1 receptors GPCR downstream signalling G alpha (i) signalling events 4 genes G alpha (i) signalling events (5 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Peptide ligand-binding receptors Chemokine receptors bind chemokines 1 genes GPCR downstream signalling G alpha (i) signalling events 4 genes G alpha (i) signalling events (2 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Peptide ligand-binding receptors Formyl peptide receptors bind formyl peptides and many other ligands GPCR downstream signalling G alpha (i) signalling events 2 genes G alpha (q) signalling events (4 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Peptide ligand-binding receptors Vasopressin-like receptors GPCR downstream signalling G alpha (q) signalling events 4 genes G alpha (q) signalling events (6 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Adrenoceptors GPCR downstream signalling G alpha (q) signalling events 6 genes G alpha (q) signalling events (4 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Nucleotide-like (purinergic) receptors P2Y receptors GPCR downstream signalling G alpha (q) signalling events 4 genes G alpha (q) signalling events (3 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Peptide ligand-binding receptors Tachykinin receptors bind tachykinins GPCR downstream signalling G alpha (q) signalling events 3 genes G alpha (q) signalling events (2 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Peptide ligand-binding receptors Orexin and neuropeptides FF and QRFP bind to their respective receptors GPCR downstream signalling G alpha (q) signalling events 2 genes G alpha (q) signalling events (4 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Muscarinic acetylcholine receptors GPCR downstream signalling G alpha (q) signalling events 4 genes G alpha (q) signalling events (1 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Eicosanoid ligand-binding receptors Leukotriene receptors GPCR downstream signalling G alpha (q) signalling events 1 genes G alpha (s) signalling events (5 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Dopamine receptors 1 genes GPCR downstream signalling G alpha (s) signalling events 4 genes G alpha (s) signalling events (8 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Serotonin receptors 1 genes GPCR downstream signalling G alpha (s) signalling events 7 genes G alpha (s) signalling events (2 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Peptide ligand-binding receptors Relaxin receptors GPCR downstream signalling G alpha (s) signalling events 2 genes G alpha (s) signalling events (2 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Eicosanoid ligand-binding receptors Prostanoid ligand receptors GPCR downstream signalling G alpha (s) signalling events 2 genes Gastrin-CREB signalling pathway via PKC and MAPK (41 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Peptide ligand-binding receptors GPCR downstream signalling G alpha (q) signalling events 39 genes Gastrin-CREB signalling pathway via PKC and MAPK 2 genes Adenylate cyclase activating pathway (1 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (i) signalling events Opioid Signalling G-protein mediated events Adenylate cyclase activating pathway 1 genes G alpha (i) signalling events (1 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Opsins GPCR downstream signalling G alpha (i) signalling events 1 genes G alpha (q) signalling events (1 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors GPCR downstream signalling G alpha (q) signalling events 1 genes G alpha (q) signalling events (5 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Lysosphingolipid and LPA receptors GPCR downstream signalling G alpha (q) signalling events 5 genes G alpha (s) signalling events (8 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class B/2 (Secretin family receptors) Glucagon-type ligand receptors GPCR downstream signalling G alpha (s) signalling events 8 genes G alpha (s) signalling events (3 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class B/2 (Secretin family receptors) Calcitonin-like ligand receptors GPCR downstream signalling G alpha (s) signalling events 3 genes G alpha (s) signalling events (1 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors GPCR downstream signalling G alpha (s) signalling events 1 genes PLC beta mediated events (2 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (i) signalling events Opioid Signalling G-protein mediated events PLC beta mediated events 2 genes Class C/3 (Metabotropic glutamate/pheromone receptors) (11 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (i) signalling events 6 genes GPCR ligand binding Class C/3 (Metabotropic glutamate/pheromone receptors) 5 genes Class C/3 (Metabotropic glutamate/pheromone receptors) (11 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (q) signalling events 8 genes GPCR ligand binding Class C/3 (Metabotropic glutamate/pheromone receptors) 3 genes DARPP-32 events (1 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (i) signalling events Opioid Signalling DARPP-32 events 1 genes EGFR Transactivation by Gastrin (1 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK EGFR Transactivation by Gastrin 1 genes G alpha (q) signalling events (7 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) 1 genes GPCR downstream signalling G alpha (q) signalling events 6 genes G alpha (s) signalling events (6 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class B/2 (Secretin family receptors) 2 genes GPCR downstream signalling G alpha (s) signalling events 4 genes Histamine receptors (1 genes) Signal Transduction Signaling by GPCR GPCR ligand binding Class A/1 (Rhodopsin-like receptors) Amine ligand-binding receptors Histamine receptors 1 genes G beta:gamma signalling through PI3Kgamma (1 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G-protein beta:gamma signalling G beta:gamma signalling through PI3Kgamma 1 genes GPER1 signaling (1 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (s) signalling events GPER1 signaling 1 genes Gastrin-CREB signalling pathway via PKC and MAPK (2 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (q) signalling events Gastrin-CREB signalling pathway via PKC and MAPK 2 genes G alpha (12/13) signalling events (2 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (12/13) signalling events 2 genes G alpha (s) signalling events (7 genes) Signal Transduction Signaling by GPCR GPCR downstream signalling G alpha (s) signalling events 7 genes	Adcy1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020431 Description: adenylate cyclase 1 [Source:MGI Symbol;Acc:MGI:99677] Location: 11:7013489-7128506 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Transmission across Chemical Synapses Signaling by GPCR Signaling by Hedgehog Adcy2 Gene Information Basic Information Ensembl ID: ENSMUSG00000021536 Description: adenylate cyclase 2 [Source:MGI Symbol;Acc:MGI:99676] Location: 13:68768162-69147660 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell skeletal muscle cell excitatory neuron Other: Transmission across Chemical Synapses Signaling by GPCR Signaling by Hedgehog Adcy5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022840 Description: adenylate cyclase 5 [Source:MGI Symbol;Acc:MGI:99673] Location: 16:34975247-35126108 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell projection neuron Other: Transmission across Chemical Synapses Integration of energy metabolism Signaling by GPCR Adcyap1 Gene Information Basic Information Ensembl ID: ENSMUSG00000024256 Description: adenylate cyclase activating polypeptide 1 [Source:MGI Symbol;Acc:MGI:105094] Location: 17:93506445-93513965 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Adgre1 Gene Information Basic Information Ensembl ID: ENSMUSG00000004730 Description: adhesion G protein-coupled receptor E1 [Source:MGI Symbol;Acc:MGI:106912] Location: 17:57665691-57790527 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte microglia antigen presenting cell T cell macrophage monocyte lymphocyte eosinophil myeloid cell Naive B cell kupffer cell Other: Signaling by GPCR Adora1 Gene Information Basic Information Ensembl ID: ENSMUSG00000042429 Description: adenosine A1 receptor [Source:MGI Symbol;Acc:MGI:99401] Location: 1:134126963-134163169 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Signaling by GPCR Adora2a Gene Information Basic Information Ensembl ID: ENSMUSG00000020178 Description: adenosine A2a receptor [Source:MGI Symbol;Acc:MGI:99402] Location: 10:75152711-75170618 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Surfactant metabolism Adora2b Gene Information Basic Information Ensembl ID: ENSMUSG00000018500 Description: adenosine A2b receptor [Source:MGI Symbol;Acc:MGI:99403] Location: 11:62139810-62157279 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: eosinophil Other: Signaling by GPCR Surfactant metabolism Adora3 Gene Information Basic Information Ensembl ID: ENSMUSG00000000562 Description: adenosine A3 receptor [Source:MGI Symbol;Acc:MGI:104847] Location: 3:105778174-105816242 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mast cell Other: Signaling by GPCR Adra1a Gene Information Basic Information Ensembl ID: ENSMUSG00000045875 Description: adrenergic receptor%2C alpha 1a [Source:MGI Symbol;Acc:MGI:104773] Location: 14:66872700-67008617 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: adipocyte interneuron Other: Signaling by GPCR Adra1b Gene Information Basic Information Ensembl ID: ENSMUSG00000050541 Description: adrenergic receptor%2C alpha 1b [Source:MGI Symbol;Acc:MGI:104774] Location: 11:43665433-43792037 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell Other: Signaling by GPCR Adra1d Gene Information Basic Information Ensembl ID: ENSMUSG00000027335 Description: adrenergic receptor%2C alpha 1d [Source:MGI Symbol;Acc:MGI:106673] Location: 2:131387770-131404203 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Adra2c Gene Information Basic Information Ensembl ID: ENSMUSG00000045318 Description: adrenergic receptor%2C alpha 2c [Source:MGI Symbol;Acc:MGI:87936] Location: 5:35435663-35439107 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Integration of energy metabolism Signaling by GPCR Surfactant metabolism Adrb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000045730 Description: adrenergic receptor%2C beta 2 [Source:MGI Symbol;Acc:MGI:87938] Location: 18:62310887-62313030 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell erythroblast Other: Membrane Trafficking Signaling by GPCR Post-translational protein modification Adrb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000031489 Description: adrenergic receptor%2C beta 3 [Source:MGI Symbol;Acc:MGI:87939] Location: 8:27715804-27740644 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: adipocyte Other: Signaling by GPCR Agtr1a Gene Information Basic Information Ensembl ID: ENSMUSG00000049115 Description: angiotensin II receptor%2C type 1a [Source:MGI Symbol;Acc:MGI:87964] Location: 13:30520424-30566850 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell pericyte stellate cell fibroblast adrenal cortical cell Other: Membrane Trafficking Signaling by GPCR Agtr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000068122 Description: angiotensin II receptor%2C type 2 [Source:MGI Symbol;Acc:MGI:87966] Location: X:21350783-21355403 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast Other: Signaling by GPCR Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Aplnr Gene Information Basic Information Ensembl ID: ENSMUSG00000044338 Description: apelin receptor [Source:MGI Symbol;Acc:MGI:1346086] Location: 2:84966569-84970267 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell pericyte Other: Signaling by GPCR Arhgef7 Gene Information Basic Information Ensembl ID: ENSMUSG00000031511 Description: Rho guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1860493] Location: 8:11777721-11885219 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell smooth muscle cell Other: Signaling by GPCR Death Receptor Signaling Signaling by Receptor Tyrosine Kinases Avpr1a Gene Information Basic Information Ensembl ID: ENSMUSG00000020123 Description: arginine vasopressin receptor 1A [Source:MGI Symbol;Acc:MGI:1859216] Location: 10:122284404-122289357 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Avpr1b Gene Information Basic Information Ensembl ID: ENSMUSG00000026432 Description: arginine vasopressin receptor 1B [Source:MGI Symbol;Acc:MGI:1347010] Location: 1:131526977-131539738 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Avpr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031390 Description: arginine vasopressin receptor 2 [Source:MGI Symbol;Acc:MGI:88123] Location: X:72935708-72939108 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Membrane Trafficking Signaling by GPCR Aquaporin-mediated transport C3 Gene Information Basic Information Ensembl ID: ENSMUSG00000024164 Description: complement component 3 [Source:MGI Symbol;Acc:MGI:88227] Location: 17:57510970-57535136 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell fibroblast stellate cell stem cell endothelial cell stromal cell epithelial cell hepatocyte Other: Adaptive Immune System Innate Immune System Signaling by GPCR C3ar1 Gene Information Basic Information Ensembl ID: ENSMUSG00000040552 Description: complement component 3a receptor 1 [Source:MGI Symbol;Acc:MGI:1097680] Location: 6:122824097-122833120 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte basophil T cell monocyte macrophage leukocyte microglia Other: Innate Immune System Signaling by GPCR C5ar1 Gene Information Basic Information Ensembl ID: ENSMUSG00000049130 Description: complement component 5a receptor 1 [Source:MGI Symbol;Acc:MGI:88232] Location: 7:15980668-15993465 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell phagocyte granulocyte myeloid cell T cell monocyte macrophage leukocyte Other: Innate Immune System Signaling by GPCR Calcr Gene Information Basic Information Ensembl ID: ENSMUSG00000023964 Description: calcitonin receptor [Source:MGI Symbol;Acc:MGI:101950] Location: 6:3685680-3764714 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stem cell intercalated cell Other: Signaling by GPCR Casr Gene Information Basic Information Ensembl ID: ENSMUSG00000051980 Description: calcium-sensing receptor [Source:MGI Symbol;Acc:MGI:1351351] Location: 16:36314058-36382503 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Cckar Gene Information Basic Information Ensembl ID: ENSMUSG00000029193 Description: cholecystokinin A receptor [Source:MGI Symbol;Acc:MGI:99478] Location: 5:53855118-53865047 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pancreatic cell Other: Signaling by GPCR Cckbr Gene Information Basic Information Ensembl ID: ENSMUSG00000030898 Description: cholecystokinin B receptor [Source:MGI Symbol;Acc:MGI:99479] Location: 7:105074938-105120105 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Ccr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025804 Description: C-C motif chemokine receptor 1 [Source:MGI Symbol;Acc:MGI:104618] Location: 9:123762161-123768729 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell dendritic cell phagocyte granulocyte eosinophil leukocyte Other: Signaling by GPCR Ccr6 Gene Information Basic Information Ensembl ID: ENSMUSG00000040899 Description: C-C motif chemokine receptor 6 [Source:MGI Symbol;Acc:MGI:1333797] Location: 17:8454875-8475973 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: memory B cell innate lymphoid cell Other: Innate Immune System Signaling by GPCR Ccrl2 Gene Information Basic Information Ensembl ID: ENSMUSG00000043953 Description: C-C motif chemokine receptor-like 2 [Source:MGI Symbol;Acc:MGI:1920904] Location: 9:110883554-110886587 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell pericyte dendritic cell phagocyte mast cell granulocyte Other: Signaling by GPCR Chrm1 Gene Information Basic Information Ensembl ID: ENSMUSG00000032773 Description: cholinergic receptor%2C muscarinic 1%2C CNS [Source:MGI Symbol;Acc:MGI:88396] Location: 19:8641153-8660951 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: chromaffin cell Other: Signaling by GPCR Chrm2 Gene Information Basic Information Ensembl ID: ENSMUSG00000045613 Description: cholinergic receptor%2C muscarinic 2%2C cardiac [Source:MGI Symbol;Acc:MGI:88397] Location: 6:36365019-36505349 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cardiomyocyte excitatory neuron Other: Membrane Trafficking Signaling by GPCR Chrm3 Gene Information Basic Information Ensembl ID: ENSMUSG00000046159 Description: cholinergic receptor%2C muscarinic 3%2C cardiac [Source:MGI Symbol;Acc:MGI:88398] Location: 13:9925522-10410883 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell endocrine cell neuron Other: Signaling by GPCR Chrm5 Gene Information Basic Information Ensembl ID: ENSMUSG00000074939 Description: cholinergic receptor%2C muscarinic 5 [Source:MGI Symbol;Acc:MGI:109248] Location: 2:112309516-112311114 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Cmklr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000042190 Description: chemerin chemokine-like receptor 1 [Source:MGI Symbol;Acc:MGI:109603] Location: 5:113750415-113788487 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Cnr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000044288 Description: cannabinoid receptor 1 [Source:MGI Symbol;Acc:MGI:104615] Location: 4:33924593-33948831 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Crh Gene Information Basic Information Ensembl ID: ENSMUSG00000049796 Description: corticotropin releasing hormone [Source:MGI Symbol;Acc:MGI:88496] Location: 3:19747565-19749560 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron neuron Other: Signaling by GPCR Crhbp Gene Information Basic Information Ensembl ID: ENSMUSG00000021680 Description: corticotropin releasing hormone binding protein [Source:MGI Symbol;Acc:MGI:88497] Location: 13:95567879-95581432 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Crhr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000018634 Description: corticotropin releasing hormone receptor 1 [Source:MGI Symbol;Acc:MGI:88498] Location: 11:104023681-104066349 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: leydig cell Other: Signaling by GPCR Crhr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003476 Description: corticotropin releasing hormone receptor 2 [Source:MGI Symbol;Acc:MGI:894312] Location: 6:55067034-55110001 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Cxcl12 Gene Information Basic Information Ensembl ID: ENSMUSG00000061353 Description: C-X-C motif chemokine ligand 12 [Source:MGI Symbol;Acc:MGI:103556] Location: 6:117145496-117158328 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stellate cell epithelial cell fibroblast stromal cell smooth muscle cell Other: Signaling by GPCR Nervous system development Cxcr4 Gene Information Basic Information Ensembl ID: ENSMUSG00000045382 Description: C-X-C motif chemokine receptor 4 [Source:MGI Symbol;Acc:MGI:109563] Location: 1:128515936-128520030 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell mast cell monocyte eosinophil progenitor cell Other: Signaling by GPCR Nervous system development Cxcr5 Gene Information Basic Information Ensembl ID: ENSMUSG00000047880 Description: C-X-C motif chemokine receptor 5 [Source:MGI Symbol;Acc:MGI:103567] Location: 9:44423084-44473174 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell T helper cell Other: Signaling by GPCR Dgkb Gene Information Basic Information Ensembl ID: ENSMUSG00000036095 Description: diacylglycerol kinase%2C beta [Source:MGI Symbol;Acc:MGI:2442474] Location: 12:37867725-38684238 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte glial cell smooth muscle cell Other: Signaling by GPCR Platelet activation, signaling and aggregation Dgkk Gene Information Basic Information Ensembl ID: ENSMUSG00000062393 Description: diacylglycerol kinase kappa [Source:MGI Symbol;Acc:MGI:3580254] Location: X:6690410-6814602 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet activation, signaling and aggregation Drd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000021478 Description: dopamine receptor D1 [Source:MGI Symbol;Acc:MGI:99578] Location: 13:54205202-54209724 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Drd2 Gene Information Basic Information Ensembl ID: ENSMUSG00000032259 Description: dopamine receptor D2 [Source:MGI Symbol;Acc:MGI:94924] Location: 9:49251927-49319477 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: retina cell projection neuron Other: Signaling by GPCR Drd3 Gene Information Basic Information Ensembl ID: ENSMUSG00000022705 Description: dopamine receptor D3 [Source:MGI Symbol;Acc:MGI:94925] Location: 16:43574389-43643295 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Signaling by GPCR Drd4 Gene Information Basic Information Ensembl ID: ENSMUSG00000025496 Description: dopamine receptor D4 [Source:MGI Symbol;Acc:MGI:94926] Location: 7:140871919-140876377 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Signaling by GPCR Drd5 Gene Information Basic Information Ensembl ID: ENSMUSG00000039358 Description: dopamine receptor D5 [Source:MGI Symbol;Acc:MGI:94927] Location: 5:38476710-38479861 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Ednra Gene Information Basic Information Ensembl ID: ENSMUSG00000031616 Description: endothelin receptor type A [Source:MGI Symbol;Acc:MGI:105923] Location: 8:78389660-78451093 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stellate cell mast cell mural cell Other: Signaling by GPCR Ednrb Gene Information Basic Information Ensembl ID: ENSMUSG00000022122 Description: endothelin receptor type B [Source:MGI Symbol;Acc:MGI:102720] Location: 14:104052061-104081838 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell endothelial cell glial cell oligodendrocyte precursor cell mural cell macrophage epithelial cell melanocyte pneumocyte capillary cell Other: Signaling by GPCR Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Fpr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000045551 Description: formyl peptide receptor 1 [Source:MGI Symbol;Acc:MGI:107443] Location: 17:18096733-18104202 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell mast cell neutrophil Other: Innate Immune System Signaling by GPCR Fpr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000079700 Description: formyl peptide receptor 3 [Source:MGI Symbol;Acc:MGI:1194495] Location: 17:18108114-18191939 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Fshr Gene Information Basic Information Ensembl ID: ENSMUSG00000032937 Description: follicle stimulating hormone receptor [Source:MGI Symbol;Acc:MGI:95583] Location: 17:89292380-89508103 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Gabbr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000039809 Description: gamma-aminobutyric acid type B receptor subunit 2 [Source:MGI Symbol;Acc:MGI:2386030] Location: 4:46662305-46991873 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron sensory neuron Other: Transmission across Chemical Synapses Potassium Channels Signaling by GPCR Gal Gene Information Basic Information Ensembl ID: ENSMUSG00000024907 Description: galanin and GMAP prepropeptide [Source:MGI Symbol;Acc:MGI:95637] Location: 19:3459915-3464544 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: skeletal muscle cell Other: Signaling by GPCR Galr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000024553 Description: galanin receptor 1 [Source:MGI Symbol;Acc:MGI:1096364] Location: 18:82410505-82424902 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Galr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000020793 Description: galanin receptor 2 [Source:MGI Symbol;Acc:MGI:1337018] Location: 11:116171765-116174764 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Gcgr Gene Information Basic Information Ensembl ID: ENSMUSG00000025127 Description: glucagon receptor [Source:MGI Symbol;Acc:MGI:99572] Location: 11:120421525-120429812 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Integration of energy metabolism Signaling by GPCR Ghrhr Gene Information Basic Information Ensembl ID: ENSMUSG00000004654 Description: growth hormone releasing hormone receptor [Source:MGI Symbol;Acc:MGI:95710] Location: 6:55353280-55365515 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Glp1r Gene Information Basic Information Ensembl ID: ENSMUSG00000024027 Description: glucagon-like peptide 1 receptor [Source:MGI Symbol;Acc:MGI:99571] Location: 17:31120791-31159765 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Integration of energy metabolism Signaling by GPCR Glp2r Gene Information Basic Information Ensembl ID: ENSMUSG00000049928 Description: glucagon-like peptide 2 receptor [Source:MGI Symbol;Acc:MGI:2136733] Location: 11:67552328-67661979 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron phagocyte Other: Signaling by GPCR Gnal Gene Information Basic Information Ensembl ID: ENSMUSG00000024524 Description: guanine nucleotide binding protein%2C alpha stimulating%2C olfactory type [Source:MGI Symbol;Acc:MGI:95774] Location: 18:67221287-67359863 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Signaling by GPCR Olfactory Signaling Pathway Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Gper1 Gene Information Basic Information Ensembl ID: ENSMUSG00000053647 Description: G protein-coupled estrogen receptor 1 [Source:MGI Symbol;Acc:MGI:1924104] Location: 5:139408906-139413555 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Gpr143 Gene Information Basic Information Ensembl ID: ENSMUSG00000025333 Description: G protein-coupled receptor 143 [Source:MGI Symbol;Acc:MGI:107193] Location: X:151564917-151591642 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: melanocyte Other: Signaling by GPCR Gpr150 Gene Information Basic Information Ensembl ID: ENSMUSG00000045509 Description: G protein-coupled receptor 150 [Source:MGI Symbol;Acc:MGI:2441872] Location: 13:76202970-76205115 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Gpr17 Gene Information Basic Information Ensembl ID: ENSMUSG00000052229 Description: G protein-coupled receptor 17 [Source:MGI Symbol;Acc:MGI:3584514] Location: 18:32076050-32082689 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: oligodendrocyte Other: Signaling by GPCR Gpr183 Gene Information Basic Information Ensembl ID: ENSMUSG00000051212 Description: G protein-coupled receptor 183 [Source:MGI Symbol;Acc:MGI:2442034] Location: 14:122189963-122202607 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell developing T cell Naive B cell Other: Signaling by GPCR Gpr37 Gene Information Basic Information Ensembl ID: ENSMUSG00000039904 Description: G protein-coupled receptor 37 [Source:MGI Symbol;Acc:MGI:1313297] Location: 6:25665877-25690728 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell oligodendrocyte Other: Signaling by GPCR Gpr37l1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026424 Description: G protein-coupled receptor 37-like 1 [Source:MGI Symbol;Acc:MGI:1928503] Location: 1:135087972-135095419 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron glial cell Other: Signaling by GPCR Gpr39 Gene Information Basic Information Ensembl ID: ENSMUSG00000026343 Description: G protein-coupled receptor 39 [Source:MGI Symbol;Acc:MGI:1918361] Location: 1:125604732-125801599 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Gpr4 Gene Information Basic Information Ensembl ID: ENSMUSG00000044317 Description: G protein-coupled receptor 4 [Source:MGI Symbol;Acc:MGI:2441992] Location: 7:18946463-18958099 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Gpr55 Gene Information Basic Information Ensembl ID: ENSMUSG00000049608 Description: G protein-coupled receptor 55 [Source:MGI Symbol;Acc:MGI:2685064] Location: 1:85866039-85888729 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Gpr83 Gene Information Basic Information Ensembl ID: ENSMUSG00000031932 Description: G protein-coupled receptor 83 [Source:MGI Symbol;Acc:MGI:95712] Location: 9:14771506-14782085 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Grk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000042249 Description: G protein-coupled receptor kinase 3 [Source:MGI Symbol;Acc:MGI:87941] Location: 5:113058348-113163657 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bone cell monocyte dendritic cell Other: Membrane Trafficking Signaling by GPCR Grm1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019828 Description: glutamate receptor%2C metabotropic 1 [Source:MGI Symbol;Acc:MGI:1351338] Location: 10:10561803-10958100 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron interneuron cajal-retzius cell Other: Signaling by GPCR Protein-protein interactions at synapses Grm3 Gene Information Basic Information Ensembl ID: ENSMUSG00000003974 Description: glutamate receptor%2C metabotropic 3 [Source:MGI Symbol;Acc:MGI:1351340] Location: 5:9535541-9775170 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte glial cell stromal cell Other: Signaling by GPCR Grm4 Gene Information Basic Information Ensembl ID: ENSMUSG00000063239 Description: glutamate receptor%2C metabotropic 4 [Source:MGI Symbol;Acc:MGI:1351341] Location: 17:27641361-27740377 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Signaling by GPCR Grm5 Gene Information Basic Information Ensembl ID: ENSMUSG00000049583 Description: glutamate receptor%2C metabotropic 5 [Source:MGI Symbol;Acc:MGI:1351342] Location: 7:87233376-87784115 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Signaling by GPCR Protein-protein interactions at synapses Grm7 Gene Information Basic Information Ensembl ID: ENSMUSG00000056755 Description: glutamate receptor%2C metabotropic 7 [Source:MGI Symbol;Acc:MGI:1351344] Location: 6:110622542-111544191 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte neuron stromal cell excitatory neuron Other: Signaling by GPCR Grm8 Gene Information Basic Information Ensembl ID: ENSMUSG00000024211 Description: glutamate receptor%2C metabotropic 8 [Source:MGI Symbol;Acc:MGI:1351345] Location: 6:27275118-28135177 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell excitatory neuron Other: Signaling by GPCR Grp Gene Information Basic Information Ensembl ID: ENSMUSG00000024517 Description: gastrin releasing peptide [Source:MGI Symbol;Acc:MGI:95833] Location: 18:66005891-66019667 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: basal cell Other: Peptide hormone metabolism Signaling by GPCR Grpr Gene Information Basic Information Ensembl ID: ENSMUSG00000031364 Description: gastrin releasing peptide receptor [Source:MGI Symbol;Acc:MGI:95836] Location: X:162296900-162332673 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Hcrtr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000032360 Description: hypocretin (orexin) receptor 2 [Source:MGI Symbol;Acc:MGI:2680765] Location: 9:76133162-76231138 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Hrh3 Gene Information Basic Information Ensembl ID: ENSMUSG00000039059 Description: histamine receptor H3 [Source:MGI Symbol;Acc:MGI:2139279] Location: 2:179741258-179746281 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Htr1a Gene Information Basic Information Ensembl ID: ENSMUSG00000021721 Description: 5-hydroxytryptamine (serotonin) receptor 1A [Source:MGI Symbol;Acc:MGI:96273] Location: 13:105580147-105584630 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Htr1b Gene Information Basic Information Ensembl ID: ENSMUSG00000049511 Description: 5-hydroxytryptamine (serotonin) receptor 1B [Source:MGI Symbol;Acc:MGI:96274] Location: 9:81510344-81515881 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Htr1d Gene Information Basic Information Ensembl ID: ENSMUSG00000070687 Description: 5-hydroxytryptamine (serotonin) receptor 1D [Source:MGI Symbol;Acc:MGI:96276] Location: 4:136150835-136171709 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Htr2a Gene Information Basic Information Ensembl ID: ENSMUSG00000034997 Description: 5-hydroxytryptamine (serotonin) receptor 2A [Source:MGI Symbol;Acc:MGI:109521] Location: 14:74878280-74946934 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Htr2c Gene Information Basic Information Ensembl ID: ENSMUSG00000041380 Description: 5-hydroxytryptamine (serotonin) receptor 2C [Source:MGI Symbol;Acc:MGI:96281] Location: X:145745509-145980273 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell excitatory neuron Other: Signaling by GPCR Htr4 Gene Information Basic Information Ensembl ID: ENSMUSG00000026322 Description: 5 hydroxytryptamine (serotonin) receptor 4 [Source:MGI Symbol;Acc:MGI:109246] Location: 18:62457275-62629648 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Htr6 Gene Information Basic Information Ensembl ID: ENSMUSG00000028747 Description: 5-hydroxytryptamine (serotonin) receptor 6 [Source:MGI Symbol;Acc:MGI:1196627] Location: 4:138788419-138802881 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Htr7 Gene Information Basic Information Ensembl ID: ENSMUSG00000024798 Description: 5-hydroxytryptamine (serotonin) receptor 7 [Source:MGI Symbol;Acc:MGI:99841] Location: 19:35936134-36034907 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Lpar1 Gene Information Basic Information Ensembl ID: ENSMUSG00000038668 Description: lysophosphatidic acid receptor 1 [Source:MGI Symbol;Acc:MGI:108429] Location: 4:58435255-58553898 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast glial cell Other: Signaling by GPCR Lpar2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031861 Description: lysophosphatidic acid receptor 2 [Source:MGI Symbol;Acc:MGI:1858422] Location: 8:70275079-70283752 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Lpar3 Gene Information Basic Information Ensembl ID: ENSMUSG00000036832 Description: lysophosphatidic acid receptor 3 [Source:MGI Symbol;Acc:MGI:1929469] Location: 3:145926718-145991941 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Lpar6 Gene Information Basic Information Ensembl ID: ENSMUSG00000033446 Description: lysophosphatidic acid receptor 6 [Source:MGI Symbol;Acc:MGI:1914418] Location: 14:73475335-73480734 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell Specialized T cell Other: Signaling by GPCR Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mc2r Gene Information Basic Information Ensembl ID: ENSMUSG00000045569 Description: melanocortin 2 receptor [Source:MGI Symbol;Acc:MGI:96928] Location: 18:68539978-68562391 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: adrenal cortical cell Other: Signaling by GPCR Mc3r Gene Information Basic Information Ensembl ID: ENSMUSG00000038537 Description: melanocortin 3 receptor [Source:MGI Symbol;Acc:MGI:96929] Location: 2:172090412-172093034 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Mc4r Gene Information Basic Information Ensembl ID: ENSMUSG00000047259 Description: melanocortin 4 receptor [Source:MGI Symbol;Acc:MGI:99457] Location: 18:66990775-66993577 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Mc5r Gene Information Basic Information Ensembl ID: ENSMUSG00000007480 Description: melanocortin 5 receptor [Source:MGI Symbol;Acc:MGI:99420] Location: 18:68470575-68475517 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Mchr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000050164 Description: melanin-concentrating hormone receptor 1 [Source:MGI Symbol;Acc:MGI:2180756] Location: 15:81119700-81123165 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Cilium Assembly Ngef Gene Information Basic Information Ensembl ID: ENSMUSG00000026259 Description: neuronal guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1858414] Location: 1:87404556-87501592 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Death Receptor Signaling Nervous system development Npbwr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000033774 Description: neuropeptides B/W receptor 1 [Source:MGI Symbol;Acc:MGI:891989] Location: 1:5983926-5987617 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Npffr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035528 Description: neuropeptide FF receptor 2 [Source:MGI Symbol;Acc:MGI:1860130] Location: 5:89675288-89731599 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Npsr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000043659 Description: neuropeptide S receptor 1 [Source:MGI Symbol;Acc:MGI:2441738] Location: 9:24009292-24227694 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Npy1r Gene Information Basic Information Ensembl ID: ENSMUSG00000036437 Description: neuropeptide Y receptor Y1 [Source:MGI Symbol;Acc:MGI:104963] Location: 8:67149844-67159444 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell mural cell Other: Signaling by GPCR Npy2r Gene Information Basic Information Ensembl ID: ENSMUSG00000028004 Description: neuropeptide Y receptor Y2 [Source:MGI Symbol;Acc:MGI:108418] Location: 3:82445690-82455391 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Nts Gene Information Basic Information Ensembl ID: ENSMUSG00000019890 Description: neurotensin [Source:MGI Symbol;Acc:MGI:1328351] Location: 10:102317617-102326347 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: enteroendocrine cell endothelial cell Other: Signaling by GPCR Ntsr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027568 Description: neurotensin receptor 1 [Source:MGI Symbol;Acc:MGI:97386] Location: 2:180141769-180186773 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Ntsr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000020591 Description: neurotensin receptor 2 [Source:MGI Symbol;Acc:MGI:108018] Location: 12:16703383-16710228 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell Other: Signaling by GPCR Opn3 Gene Information Basic Information Ensembl ID: ENSMUSG00000026525 Description: opsin 3 [Source:MGI Symbol;Acc:MGI:1338022] Location: 1:175489987-175520342 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Oprd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000050511 Description: opioid receptor%2C delta 1 [Source:MGI Symbol;Acc:MGI:97438] Location: 4:131838037-131871797 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Oprk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025905 Description: opioid receptor%2C kappa 1 [Source:MGI Symbol;Acc:MGI:97439] Location: 1:5658689-5676354 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Oprm1 Gene Information Basic Information Ensembl ID: ENSMUSG00000000766 Description: opioid receptor%2C mu 1 [Source:MGI Symbol;Acc:MGI:97441] Location: 10:6708506-6988198 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Specialized T cell Other: Signaling by GPCR Oxtr Gene Information Basic Information Ensembl ID: ENSMUSG00000049112 Description: oxytocin receptor [Source:MGI Symbol;Acc:MGI:109147] Location: 6:112450644-112466904 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR P2ry1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027765 Description: purinergic receptor P2Y%2C G-protein coupled 1 [Source:MGI Symbol;Acc:MGI:105049] Location: 3:60910216-60916403 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet activation, signaling and aggregation P2ry13 Gene Information Basic Information Ensembl ID: ENSMUSG00000036362 Description: purinergic receptor P2Y%2C G-protein coupled 13 [Source:MGI Symbol;Acc:MGI:1921441] Location: 3:59115313-59118303 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte Other: Signaling by GPCR P2ry14 Gene Information Basic Information Ensembl ID: ENSMUSG00000036381 Description: purinergic receptor P2Y%2C G-protein coupled%2C 14 [Source:MGI Symbol;Acc:MGI:2155705] Location: 3:59021276-59061039 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell pericyte smooth muscle cell fibroblast mast cell dendritic cell myeloid progenitor cell Other: Signaling by GPCR Pcp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000004630 Description: Purkinje cell protein 2 (L7) [Source:MGI Symbol;Acc:MGI:97508] Location: 8:3673371-3675545 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron neuron Other: Signaling by GPCR Pde10a Gene Information Basic Information Ensembl ID: ENSMUSG00000023868 Description: phosphodiesterase 10A [Source:MGI Symbol;Acc:MGI:1345143] Location: 17:8744204-9205480 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron stem cell epithelial cell Other: Signaling by GPCR Platelet homeostasis Pde11a Gene Information Basic Information Ensembl ID: ENSMUSG00000075270 Description: phosphodiesterase 11A [Source:MGI Symbol;Acc:MGI:3036251] Location: 2:75819485-76169118 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron enteroendocrine cell Other: Signaling by GPCR Platelet homeostasis Pde1a Gene Information Basic Information Ensembl ID: ENSMUSG00000059173 Description: phosphodiesterase 1A%2C calmodulin-dependent [Source:MGI Symbol;Acc:MGI:1201792] Location: 2:79664797-79959802 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell preadipocyte stellate cell smooth muscle cell neuron Other: Signaling by GPCR Platelet homeostasis Intracellular signaling by second messengers Pde1b Gene Information Basic Information Ensembl ID: ENSMUSG00000022489 Description: phosphodiesterase 1B%2C Ca2+-calmodulin dependent [Source:MGI Symbol;Acc:MGI:97523] Location: 15:103411461-103438479 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet homeostasis Intracellular signaling by second messengers Pde3a Gene Information Basic Information Ensembl ID: ENSMUSG00000041741 Description: phosphodiesterase 3A%2C cGMP inhibited [Source:MGI Symbol;Acc:MGI:1860764] Location: 6:141194995-141453174 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte epithelial cell fibroblast smooth muscle cell retina cell mural cell megakaryocyte Other: Signaling by GPCR Pde8a Gene Information Basic Information Ensembl ID: ENSMUSG00000025584 Description: phosphodiesterase 8A [Source:MGI Symbol;Acc:MGI:1277116] Location: 7:80863344-80984281 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: oligodendrocyte Other: Signaling by GPCR Pdyn Gene Information Basic Information Ensembl ID: ENSMUSG00000027400 Description: prodynorphin [Source:MGI Symbol;Acc:MGI:97535] Location: 2:129528485-129541764 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Penk Gene Information Basic Information Ensembl ID: ENSMUSG00000045573 Description: preproenkephalin [Source:MGI Symbol;Acc:MGI:104629] Location: 4:4133531-4138819 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell epithelial cell Other: Signaling by GPCR Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Plcb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000051177 Description: phospholipase C%2C beta 1 [Source:MGI Symbol;Acc:MGI:97613] Location: 2:134627987-135317178 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell epithelial cell endothelial cell adipocyte Other: Transmission across Chemical Synapses Inositol phosphate metabolism Integration of energy metabolism Plcb4 Gene Information Basic Information Ensembl ID: ENSMUSG00000039943 Description: phospholipase C%2C beta 4 [Source:MGI Symbol;Acc:MGI:107464] Location: 2:135500931-135856513 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell neuron epithelial cell Other: Inositol phosphate metabolism Signaling by GPCR Pnoc Gene Information Basic Information Ensembl ID: ENSMUSG00000045731 Description: prepronociceptin [Source:MGI Symbol;Acc:MGI:105308] Location: 14:65638122-65662921 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Pomc Gene Information Basic Information Ensembl ID: ENSMUSG00000020660 Description: pro-opiomelanocortin-alpha [Source:MGI Symbol;Acc:MGI:97742] Location: 12:4004951-4010642 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Biological oxidations Peptide hormone metabolism Signaling by GPCR Ppp1r1b Gene Information Basic Information Ensembl ID: ENSMUSG00000061718 Description: protein phosphatase 1%2C regulatory inhibitor subunit 1B [Source:MGI Symbol;Acc:MGI:94860] Location: 11:98239230-98248622 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stem cell tuft cell astrocyte proximal cell Other: Signaling by GPCR Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system Prkce Gene Information Basic Information Ensembl ID: ENSMUSG00000045038 Description: protein kinase C%2C epsilon [Source:MGI Symbol;Acc:MGI:97599] Location: 17:86475213-86965347 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by GPCR Platelet activation, signaling and aggregation Prkcg Gene Information Basic Information Ensembl ID: ENSMUSG00000078816 Description: protein kinase C%2C gamma [Source:MGI Symbol;Acc:MGI:97597] Location: 7:3337704-3379615 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Signaling by WNT Signaling by GPCR Prkcq Gene Information Basic Information Ensembl ID: ENSMUSG00000026778 Description: protein kinase C%2C theta [Source:MGI Symbol;Acc:MGI:97601] Location: 2:11176919-11306033 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell CD8+ T cell Specialized T cell Other: Apoptosis Adaptive Immune System Innate Immune System Prok2 Gene Information Basic Information Ensembl ID: ENSMUSG00000030069 Description: prokineticin 2 [Source:MGI Symbol;Acc:MGI:1354178] Location: 6:99688260-99703353 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Ptafr Gene Information Basic Information Ensembl ID: ENSMUSG00000056529 Description: platelet-activating factor receptor [Source:MGI Symbol;Acc:MGI:106066] Location: 4:132291378-132309994 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell granulocyte T cell Other: Innate Immune System Signaling by GPCR Ptger3 Gene Information Basic Information Ensembl ID: ENSMUSG00000040016 Description: prostaglandin E receptor 3 (subtype EP3) [Source:MGI Symbol;Acc:MGI:97795] Location: 3:157272529-157351525 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Ptger4 Gene Information Basic Information Ensembl ID: ENSMUSG00000039942 Description: prostaglandin E receptor 4 (subtype EP4) [Source:MGI Symbol;Acc:MGI:104311] Location: 15:5236142-5273668 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Pth2r Gene Information Basic Information Ensembl ID: ENSMUSG00000025946 Description: parathyroid hormone 2 receptor [Source:MGI Symbol;Acc:MGI:2180917] Location: 1:65321215-65428403 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Ramp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000034353 Description: receptor (calcitonin) activity modifying protein 1 [Source:MGI Symbol;Acc:MGI:1858418] Location: 1:91107544-91152918 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell T cell stellate cell stem cell hematopoietic stem cell CD4+ T cell epithelial cell Specialized T cell smooth muscle cell goblet cell dendritic cell mural cell innate lymphoid cell myeloid progenitor cell Other: Signaling by GPCR Ramp3 Gene Information Basic Information Ensembl ID: ENSMUSG00000041046 Description: receptor (calcitonin) activity modifying protein 3 [Source:MGI Symbol;Acc:MGI:1860292] Location: 11:6608521-6627475 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell endothelial cell innate lymphoid cell Other: Signaling by GPCR Rgs12 Gene Information Basic Information Ensembl ID: ENSMUSG00000029101 Description: regulator of G-protein signaling 12 [Source:MGI Symbol;Acc:MGI:1918979] Location: 5:35106789-35196988 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Signaling by GPCR Rgs16 Gene Information Basic Information Ensembl ID: ENSMUSG00000026475 Description: regulator of G-protein signaling 16 [Source:MGI Symbol;Acc:MGI:108407] Location: 1:153616095-153621214 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Signaling by GPCR Rgs4 Gene Information Basic Information Ensembl ID: ENSMUSG00000038530 Description: regulator of G-protein signaling 4 [Source:MGI Symbol;Acc:MGI:108409] Location: 1:169569046-169575211 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte mural cell Other: Signaling by GPCR Rgs6 Gene Information Basic Information Ensembl ID: ENSMUSG00000021219 Description: regulator of G-protein signaling 6 [Source:MGI Symbol;Acc:MGI:1354730] Location: 12:82635066-83208830 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell intercalated cell smooth muscle cell glial cell excitatory neuron Other: Signaling by GPCR Protein folding Rgs7 Gene Information Basic Information Ensembl ID: ENSMUSG00000026527 Description: regulator of G protein signaling 7 [Source:MGI Symbol;Acc:MGI:1346089] Location: 1:174886653-175320066 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron motor neuron adipocyte Other: Signaling by GPCR Protein folding Rgs9 Gene Information Basic Information Ensembl ID: ENSMUSG00000020599 Description: regulator of G-protein signaling 9 [Source:MGI Symbol;Acc:MGI:1338824] Location: 11:109116181-109188955 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell photoreceptor cell projection neuron Other: Visual phototransduction Signaling by GPCR Protein folding Rps6ka1 Gene Information Basic Information Ensembl ID: ENSMUSG00000003644 Description: ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:104558] Location: 4:133574601-133615108 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Innate Immune System Rxfp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000034009 Description: relaxin/insulin-like family peptide receptor 1 [Source:MGI Symbol;Acc:MGI:2682211] Location: 3:79548918-79645187 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Rxfp3 Gene Information Basic Information Ensembl ID: ENSMUSG00000060735 Description: relaxin family peptide receptor 3 [Source:MGI Symbol;Acc:MGI:2441827] Location: 15:11033803-11038077 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR S1pr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000067586 Description: sphingosine-1-phosphate receptor 3 [Source:MGI Symbol;Acc:MGI:1339365] Location: 13:51562675-51576833 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte smooth muscle cell mural cell mesangial cell Other: Signaling by GPCR Signaling by Nuclear Receptors S1pr5 Gene Information Basic Information Ensembl ID: ENSMUSG00000045087 Description: sphingosine-1-phosphate receptor 5 [Source:MGI Symbol;Acc:MGI:2150641] Location: 9:21154208-21159739 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: natural killer cell Other: Signaling by GPCR Sst Gene Information Basic Information Ensembl ID: ENSMUSG00000004366 Description: somatostatin [Source:MGI Symbol;Acc:MGI:98326] Location: 16:23708323-23709708 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: motor neuron enteroendocrine cell Other: Signaling by GPCR Sstr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000035431 Description: somatostatin receptor 1 [Source:MGI Symbol;Acc:MGI:98327] Location: 12:58258558-58260673 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Sstr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000047904 Description: somatostatin receptor 2 [Source:MGI Symbol;Acc:MGI:98328] Location: 11:113510168-113516854 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Sstr4 Gene Information Basic Information Ensembl ID: ENSMUSG00000037014 Description: somatostatin receptor 4 [Source:MGI Symbol;Acc:MGI:105372] Location: 2:148237264-148238687 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Tac1 Gene Information Basic Information Ensembl ID: ENSMUSG00000061762 Description: tachykinin 1 [Source:MGI Symbol;Acc:MGI:98474] Location: 6:7554879-7565834 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell projection neuron neuron Other: Signaling by GPCR Tacr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000030043 Description: tachykinin receptor 1 [Source:MGI Symbol;Acc:MGI:98475] Location: 6:82379315-82537085 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Membrane Trafficking Signaling by GPCR Tacr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000028172 Description: tachykinin receptor 3 [Source:MGI Symbol;Acc:MGI:892968] Location: 3:134534768-134640340 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Trh Gene Information Basic Information Ensembl ID: ENSMUSG00000005892 Description: thyrotropin releasing hormone [Source:MGI Symbol;Acc:MGI:98823] Location: 6:92219042-92221631 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Trhr Gene Information Basic Information Ensembl ID: ENSMUSG00000038760 Description: thyrotropin releasing hormone receptor [Source:MGI Symbol;Acc:MGI:98824] Location: 15:44059531-44099308 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Trpc7 Gene Information Basic Information Ensembl ID: ENSMUSG00000021541 Description: transient receptor potential cation channel%2C subfamily C%2C member 7 [Source:MGI Symbol;Acc:MGI:1349470] Location: 13:56920926-57043806 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Platelet homeostasis Platelet activation, signaling and aggregation Vip Gene Information Basic Information Ensembl ID: ENSMUSG00000019772 Description: vasoactive intestinal polypeptide [Source:MGI Symbol;Acc:MGI:98933] Location: 10:5589218-5597617 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron Other: Signaling by GPCR Vipr1 Gene Information Basic Information Ensembl ID: ENSMUSG00000032528 Description: vasoactive intestinal peptide receptor 1 [Source:MGI Symbol;Acc:MGI:109272] Location: 9:121471782-121502020 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell Other: Signaling by GPCR Vipr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000011171 Description: vasoactive intestinal peptide receptor 2 [Source:MGI Symbol;Acc:MGI:107166] Location: 12:116041346-116109881 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron photoreceptor cell Other: Signaling by GPCR
Signaling by Hedgehog Pathway Hierarchies & Genes Hedgehog 'on' state (1 genes) Signal Transduction Signaling by Hedgehog Hedgehog 'off' state GLI3 is processed to GLI3R by the proteasome Hedgehog 'on' state 1 genes Hedgehog 'on' state (1 genes) Signal Transduction Signaling by Hedgehog Hedgehog 'off' state Degradation of GLI1 by the proteasome Hedgehog 'on' state 1 genes Hedgehog 'on' state (4 genes) Signal Transduction Signaling by Hedgehog Hedgehog 'off' state 3 genes Hedgehog 'on' state 1 genes Release of Hh-Np from the secreting cell (1 genes) Signal Transduction Signaling by Hedgehog Hedgehog ligand biogenesis Release of Hh-Np from the secreting cell 1 genes	Adcy1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020431 Description: adenylate cyclase 1 [Source:MGI Symbol;Acc:MGI:99677] Location: 11:7013489-7128506 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Transmission across Chemical Synapses Signaling by GPCR Signaling by Hedgehog Adcy2 Gene Information Basic Information Ensembl ID: ENSMUSG00000021536 Description: adenylate cyclase 2 [Source:MGI Symbol;Acc:MGI:99676] Location: 13:68768162-69147660 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell skeletal muscle cell excitatory neuron Other: Transmission across Chemical Synapses Signaling by GPCR Signaling by Hedgehog Adcy5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022840 Description: adenylate cyclase 5 [Source:MGI Symbol;Acc:MGI:99673] Location: 16:34975247-35126108 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell projection neuron Other: Transmission across Chemical Synapses Integration of energy metabolism Signaling by GPCR Gli2 Gene Information Basic Information Ensembl ID: ENSMUSG00000048402 Description: GLI-Kruppel family member GLI2 [Source:MGI Symbol;Acc:MGI:95728] Location: 1:118761862-118981349 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: astrocyte foregut cell Other: Signaling by Hedgehog Gli3 Gene Information Basic Information Ensembl ID: ENSMUSG00000021318 Description: GLI-Kruppel family member GLI3 [Source:MGI Symbol;Acc:MGI:95729] Location: 13:15637820-15904611 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast astrocyte mesenchymal cell Other: Signaling by Hedgehog Gpc5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022112 Description: glypican 5 [Source:MGI Symbol;Acc:MGI:1194894] Location: 14:115329647-116762591 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell oligodendrocyte precursor cell Other: Metabolism of vitamins and cofactors Visual phototransduction Signaling by Hedgehog Itch Gene Information Basic Information Ensembl ID: ENSMUSG00000027598 Description: itchy%2C E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1202301] Location: 2:154975429-155068775 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Signaling by NOTCH Innate Immune System
Signaling by NODAL Pathway Hierarchies & Genes Signaling by NODAL (2 genes) Developmental Biology Signaling by NODAL 2 genes	Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system
Signaling by NOTCH Pathway Hierarchies & Genes Noncanonical activation of NOTCH3 (1 genes) Signal Transduction Signaling by NOTCH Signaling by NOTCH3 NOTCH3 Activation and Transmission of Signal to the Nucleus Noncanonical activation of NOTCH3 1 genes Activated NOTCH1 Transmits Signal to the Nucleus (1 genes) Signal Transduction Signaling by NOTCH Signaling by NOTCH1 Activated NOTCH1 Transmits Signal to the Nucleus 1 genes NOTCH1 Intracellular Domain Regulates Transcription (1 genes) Signal Transduction Signaling by NOTCH Signaling by NOTCH1 NOTCH1 Intracellular Domain Regulates Transcription 1 genes NOTCH3 Activation and Transmission of Signal to the Nucleus (1 genes) Signal Transduction Signaling by NOTCH Signaling by NOTCH3 NOTCH3 Activation and Transmission of Signal to the Nucleus 1 genes Negative regulation of NOTCH4 signaling (1 genes) Signal Transduction Signaling by NOTCH Signaling by NOTCH4 Negative regulation of NOTCH4 signaling 1 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Itch Gene Information Basic Information Ensembl ID: ENSMUSG00000027598 Description: itchy%2C E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1202301] Location: 2:154975429-155068775 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Signaling by NOTCH Innate Immune System Maml2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031925 Description: mastermind like transcriptional coactivator 2 [Source:MGI Symbol;Acc:MGI:2389460] Location: 9:13298306-13620684 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte oligodendrocyte precursor cell epithelial cell astrocyte mesenchymal cell Other: Signaling by NOTCH RNA Polymerase II Transcription Psen1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019969 Description: presenilin 1 [Source:MGI Symbol;Acc:MGI:1202717] Location: 12:83734926-83781973 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by NOTCH Death Receptor Signaling
Signaling by Non-Receptor Tyrosine Kinases Pathway Hierarchies & Genes PTK6 Activates STAT3 (1 genes) Signal Transduction Signaling by Non-Receptor Tyrosine Kinases Signaling by PTK6 PTK6 Activates STAT3 1 genes PTK6 Regulates Cell Cycle (1 genes) Signal Transduction Signaling by Non-Receptor Tyrosine Kinases Signaling by PTK6 PTK6 Regulates Cell Cycle 1 genes PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (1 genes) Signal Transduction Signaling by Non-Receptor Tyrosine Kinases Signaling by PTK6 PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 1 genes PTK6 promotes HIF1A stabilization (3 genes) Signal Transduction Signaling by Non-Receptor Tyrosine Kinases Signaling by PTK6 PTK6 promotes HIF1A stabilization 3 genes Signaling by PTK6 (3 genes) Signal Transduction Signaling by Non-Receptor Tyrosine Kinases Signaling by PTK6 3 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Ccnd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000070348 Description: cyclin D1 [Source:MGI Symbol;Acc:MGI:88313] Location: 7:144483668-144493662 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte endothelial cell glial cell dendritic cell epithelial cell Other: Chromatin modifying enzymes Cell Cycle, Mitotic RNA Polymerase II Transcription Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Erbb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000062312 Description: erb-b2 receptor tyrosine kinase 2 [Source:MGI Symbol;Acc:MGI:95410] Location: 11:98303296-98328542 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Erbb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000018166 Description: erb-b2 receptor tyrosine kinase 3 [Source:MGI Symbol;Acc:MGI:95411] Location: 10:128403392-128425521 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell schwann cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Erbb4 Gene Information Basic Information Ensembl ID: ENSMUSG00000062209 Description: erb-b2 receptor tyrosine kinase 4 [Source:MGI Symbol;Acc:MGI:104771] Location: 1:68071345-69147218 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: inhibitory neuron Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Gpnmb Gene Information Basic Information Ensembl ID: ENSMUSG00000029816 Description: glycoprotein (transmembrane) nmb [Source:MGI Symbol;Acc:MGI:1934765] Location: 6:49013480-49047863 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte epithelial cell melanocyte Other: Signaling by Non-Receptor Tyrosine Kinases Hif1a Gene Information Basic Information Ensembl ID: ENSMUSG00000021109 Description: hypoxia inducible factor 1%2C alpha subunit [Source:MGI Symbol;Acc:MGI:106918] Location: 12:73948149-73994304 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell Regulatory T cell epithelial cell retinal pigment epithelial cell dendritic cell Other: Cellular responses to stress Post-translational protein modification Signaling by Non-Receptor Tyrosine Kinases Stat3 Gene Information Basic Information Ensembl ID: ENSMUSG00000004040 Description: signal transducer and activator of transcription 3 [Source:MGI Symbol;Acc:MGI:103038] Location: 11:100775924-100830366 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Signaling by Non-Receptor Tyrosine Kinases Signaling by Receptor Tyrosine Kinases
Signaling by Nuclear Receptors Pathway Hierarchies & Genes Estrogen-dependent nuclear events downstream of ESR-membrane signaling (1 genes) Signal Transduction Signaling by Nuclear Receptors ESR-mediated signaling Extra-nuclear estrogen signaling Estrogen-dependent nuclear events downstream of ESR-membrane signaling 1 genes Estrogen-stimulated signaling through PRKCZ (1 genes) Signal Transduction Signaling by Nuclear Receptors ESR-mediated signaling Extra-nuclear estrogen signaling Estrogen-stimulated signaling through PRKCZ 1 genes Estrogen-dependent gene expression (3 genes) Signal Transduction Signaling by Nuclear Receptors ESR-mediated signaling Estrogen-dependent gene expression 3 genes Extra-nuclear estrogen signaling (7 genes) Signal Transduction Signaling by Nuclear Receptors ESR-mediated signaling Extra-nuclear estrogen signaling 7 genes RA biosynthesis pathway (1 genes) Signal Transduction Signaling by Nuclear Receptors Signaling by Retinoic Acid RA biosynthesis pathway 1 genes Signaling by Retinoic Acid (1 genes) Signal Transduction Signaling by Nuclear Receptors Signaling by Retinoic Acid 1 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Cav2 Gene Information Basic Information Ensembl ID: ENSMUSG00000000058 Description: caveolin 2 [Source:MGI Symbol;Acc:MGI:107571] Location: 6:17281184-17289114 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Signaling by Nuclear Receptors Cyp26b1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063415 Description: cytochrome P450%2C family 26%2C subfamily b%2C polypeptide 1 [Source:MGI Symbol;Acc:MGI:2176159] Location: 6:84548396-84570890 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell ectodermal cell astrocyte Other: Signaling by Nuclear Receptors Biological oxidations Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Erbb4 Gene Information Basic Information Ensembl ID: ENSMUSG00000062209 Description: erb-b2 receptor tyrosine kinase 4 [Source:MGI Symbol;Acc:MGI:104771] Location: 1:68071345-69147218 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: inhibitory neuron Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Foxa1 Gene Information Basic Information Ensembl ID: ENSMUSG00000035451 Description: forkhead box A1 [Source:MGI Symbol;Acc:MGI:1347472] Location: 12:57587414-57593702 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by Nuclear Receptors Gata3 Gene Information Basic Information Ensembl ID: ENSMUSG00000015619 Description: GATA binding protein 3 [Source:MGI Symbol;Acc:MGI:95663] Location: 2:9861889-9894845 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell epithelial cell stem cell CD4+ T cell innate lymphoid cell developing T cell mesangial cell Other: Post-translational protein modification RNA Polymerase II Transcription Signaling by Nuclear Receptors Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Igf1r Gene Information Basic Information Ensembl ID: ENSMUSG00000005533 Description: insulin-like growth factor I receptor [Source:MGI Symbol;Acc:MGI:96433] Location: 7:67602575-67883416 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell epithelial cell eosinophil mesenchymal cell Other: Signaling by Nuclear Receptors Signaling by Receptor Tyrosine Kinases Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mmp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000031740 Description: matrix metallopeptidase 2 [Source:MGI Symbol;Acc:MGI:97009] Location: 8:93553919-93580048 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Degradation of the extracellular matrix Signaling by Nuclear Receptors Nervous system development Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Rxrg Gene Information Basic Information Ensembl ID: ENSMUSG00000015843 Description: retinoid X receptor gamma [Source:MGI Symbol;Acc:MGI:98216] Location: 1:167425953-167467192 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron photoreceptor cell inhibitory neuron Other: RNA Polymerase II Transcription Signaling by Nuclear Receptors S1pr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000067586 Description: sphingosine-1-phosphate receptor 3 [Source:MGI Symbol;Acc:MGI:1339365] Location: 13:51562675-51576833 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte smooth muscle cell mural cell mesangial cell Other: Signaling by GPCR Signaling by Nuclear Receptors
Signaling by Receptor Tyrosine Kinases Pathway Hierarchies & Genes Signaling by LTK (6 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by Insulin receptor Insulin receptor signalling cascade IRS-mediated signalling PI3K Cascade Signaling by ERBB2 PI3K events in ERBB2 signaling Signaling by ERBB4 PI3K events in ERBB4 signaling Signaling by SCF-KIT Signaling by NTRKs 1 genes Signaling by NTRK1 (TRKA) 3 genes PI3K/AKT activation Signaling by EGFR GAB1 signalosome Signaling by PDGF Downstream signal transduction Signaling by FGFR Signaling by FGFR1 1 genes Downstream signaling of activated FGFR1 PI-3K cascade:FGFR1 Signaling by VEGF VEGFA-VEGFR2 Pathway Signaling by ALK Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) IGF1R signaling cascade IRS-related events triggered by IGF1R Signaling by MET MET activates PI3K/AKT signaling Signaling by LTK 1 genes Signal attenuation (2 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by FGFR Signaling by FGFR1 Negative regulation of FGFR1 signaling Spry regulation of FGF signaling Signaling by NTRKs Signaling by NTRK1 (TRKA) Signalling to ERKs Prolonged ERK activation events Frs2-mediated activation Signaling by Insulin receptor Insulin receptor signalling cascade Signal attenuation 2 genes VEGFA-VEGFR2 Pathway (3 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by ERBB2 Signaling by SCF-KIT 2 genes Regulation of KIT signaling Signaling by NTRKs Signaling by NTRK2 (TRKB) Activated NTRK2 signals through FYN NTRK2 activates RAC1 Signaling by VEGF VEGFA-VEGFR2 Pathway 1 genes MET activates RAP1 and RAC1 (2 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by NTRKs Signaling by NTRK1 (TRKA) Signalling to ERKs Prolonged ERK activation events Frs2-mediated activation 1 genes Signaling by MET MET promotes cell motility MET activates RAP1 and RAC1 1 genes MET activates STAT3 (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by SCF-KIT Signaling by PDGF Downstream signal transduction Signaling by ALK STAT3 nuclear events downstream of ALK signaling Signaling by MET MET activates STAT3 1 genes VEGFA-VEGFR2 Pathway (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by NTRKs Signaling by NTRK1 (TRKA) Signalling to ERKs Signalling to RAS p38MAPK events Signaling by VEGF VEGFA-VEGFR2 Pathway 1 genes VEGFR2 mediated vascular permeability (3 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by ERBB2 Downregulation of ERBB2 signaling Downregulation of ERBB2:ERBB3 signaling 1 genes Signaling by VEGF 1 genes VEGFA-VEGFR2 Pathway VEGFR2 mediated vascular permeability 1 genes GRB2 events in EGFR signaling (4 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by ERBB2 SHC1 events in ERBB2 signaling 1 genes Signaling by ERBB4 Signaling by EGFR 1 genes GRB2 events in EGFR signaling 2 genes ERK/MAPK targets (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by NTRKs Signaling by NTRK1 (TRKA) Nuclear Events (kinase and transcription factor activation) ERK/MAPK targets 1 genes MET activates PTK2 signaling (3 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by PDGF 2 genes Signaling by MET MET promotes cell motility MET activates PTK2 signaling 1 genes NGF-stimulated transcription (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by NTRKs Signaling by NTRK1 (TRKA) Nuclear Events (kinase and transcription factor activation) NGF-stimulated transcription 1 genes NTRK2 activates RAC1 (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by NTRKs Signaling by NTRK2 (TRKB) Activated NTRK2 signals through FYN NTRK2 activates RAC1 1 genes FGFRL1 modulation of FGFR1 signaling (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by FGFR Signaling by FGFR1 FGFRL1 modulation of FGFR1 signaling 1 genes IRS activation (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by Insulin receptor Insulin receptor signalling cascade IRS activation 1 genes IRS-related events triggered by IGF1R (4 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) IGF1R signaling cascade IRS-related events triggered by IGF1R 4 genes MET activates PTK2 signaling (4 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by MET MET promotes cell motility MET activates PTK2 signaling 4 genes NGF processing (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by NTRKs Expression and Processing of Neurotrophins NGF processing 1 genes NTF3 activates NTRK3 signaling (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by NTRKs Signaling by NTRK3 (TRKC) NTF3 activates NTRK3 signaling 1 genes VEGF binds to VEGFR leading to receptor dimerization (4 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by VEGF VEGF ligand-receptor interactions VEGF binds to VEGFR leading to receptor dimerization 4 genes VEGFR2 mediated cell proliferation (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by VEGF VEGFA-VEGFR2 Pathway VEGFR2 mediated cell proliferation 1 genes VEGFR2 mediated vascular permeability (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by VEGF VEGFA-VEGFR2 Pathway VEGFR2 mediated vascular permeability 1 genes Downregulation of ERBB4 signaling (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by ERBB4 Downregulation of ERBB4 signaling 1 genes Downstream signal transduction (2 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by PDGF Downstream signal transduction 2 genes EGFR downregulation (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by EGFR EGFR downregulation 1 genes Insulin receptor recycling (2 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by Insulin receptor Insulin receptor recycling 2 genes Neurophilin interactions with VEGF and VEGFR (2 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by VEGF Neurophilin interactions with VEGF and VEGFR 2 genes Nuclear signaling by ERBB4 (1 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by ERBB4 Nuclear signaling by ERBB4 1 genes VEGFA-VEGFR2 Pathway (3 genes) Signal Transduction Signaling by Receptor Tyrosine Kinases Signaling by VEGF VEGFA-VEGFR2 Pathway 3 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Arhgef7 Gene Information Basic Information Ensembl ID: ENSMUSG00000031511 Description: Rho guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1860493] Location: 8:11777721-11885219 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell smooth muscle cell Other: Signaling by GPCR Death Receptor Signaling Signaling by Receptor Tyrosine Kinases Atp6v0a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019302 Description: ATPase%2C H+ transporting%2C lysosomal V0 subunit A1 [Source:MGI Symbol;Acc:MGI:103286] Location: 11:100900278-100954545 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: phagocyte eosinophil Other: Innate Immune System Signaling by Receptor Tyrosine Kinases Iron uptake and transport Atp6v1a Gene Information Basic Information Ensembl ID: ENSMUSG00000052459 Description: ATPase%2C H+ transporting%2C lysosomal V1 subunit A [Source:MGI Symbol;Acc:MGI:1201780] Location: 16:43905765-43960068 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Cellular responses to stress Signaling by Receptor Tyrosine Kinases Axl Gene Information Basic Information Ensembl ID: ENSMUSG00000002602 Description: AXL receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:1347244] Location: 7:25456698-25488130 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast pericyte stem cell phagocyte stromal cell plasma cell kupffer cell macrophage Other: Signaling by Receptor Tyrosine Kinases Baiap2 Gene Information Basic Information Ensembl ID: ENSMUSG00000025372 Description: brain-specific angiogenesis inhibitor 1-associated protein 2 [Source:MGI Symbol;Acc:MGI:2137336] Location: 11:119833589-119897608 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Innate Immune System Signaling by Receptor Tyrosine Kinases Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Bdnf Gene Information Basic Information Ensembl ID: ENSMUSG00000048482 Description: brain derived neurotrophic factor [Source:MGI Symbol;Acc:MGI:88145] Location: 2:109505045-109557352 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Col11a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027966 Description: collagen%2C type XI%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88446] Location: 3:113824189-114014367 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell Other: Degradation of the extracellular matrix Collagen formation Non-integrin membrane-ECM interactions Col5a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026837 Description: collagen%2C type V%2C alpha 1 [Source:MGI Symbol;Acc:MGI:88457] Location: 2:27776437-27929526 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell epithelial cell Other: Integrin cell surface interactions Degradation of the extracellular matrix Collagen formation Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Egfr Gene Information Basic Information Ensembl ID: ENSMUSG00000020122 Description: epidermal growth factor receptor [Source:MGI Symbol;Acc:MGI:95294] Location: 11:16702203-16868158 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stromal cell pneumocyte mesenchymal cell Other: Signaling by NOTCH Membrane Trafficking Signaling by GPCR Egr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000037868 Description: early growth response 2 [Source:MGI Symbol;Acc:MGI:95296] Location: 10:67371305-67378018 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell Other: Signaling by Receptor Tyrosine Kinases Erbb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000062312 Description: erb-b2 receptor tyrosine kinase 2 [Source:MGI Symbol;Acc:MGI:95410] Location: 11:98303296-98328542 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Erbb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000018166 Description: erb-b2 receptor tyrosine kinase 3 [Source:MGI Symbol;Acc:MGI:95411] Location: 10:128403392-128425521 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell schwann cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Erbb4 Gene Information Basic Information Ensembl ID: ENSMUSG00000062209 Description: erb-b2 receptor tyrosine kinase 4 [Source:MGI Symbol;Acc:MGI:104771] Location: 1:68071345-69147218 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: inhibitory neuron Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Non-Receptor Tyrosine Kinases Fgf10 Gene Information Basic Information Ensembl ID: ENSMUSG00000021732 Description: fibroblast growth factor 10 [Source:MGI Symbol;Acc:MGI:1099809] Location: 13:118806327-118928651 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: cochleovestibular ganglion cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Fgfr3 Gene Information Basic Information Ensembl ID: ENSMUSG00000054252 Description: fibroblast growth factor receptor 3 [Source:MGI Symbol;Acc:MGI:95524] Location: 5:33879018-33894412 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell astrocyte supporting cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Fgfrl1 Gene Information Basic Information Ensembl ID: ENSMUSG00000008090 Description: fibroblast growth factor receptor-like 1 [Source:MGI Symbol;Acc:MGI:2150920] Location: 5:108840248-108854790 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by Receptor Tyrosine Kinases Flt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029648 Description: FMS-like tyrosine kinase 1 [Source:MGI Symbol;Acc:MGI:95558] Location: 5:147498414-147662821 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Signaling by Receptor Tyrosine Kinases Fn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026193 Description: fibronectin 1 [Source:MGI Symbol;Acc:MGI:95566] Location: 1:71624679-71692359 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast stellate cell phagocyte stromal cell monocyte erythroid lineage cell dendritic cell Other: Degradation of the extracellular matrix Elastic fibre formation Fibronectin matrix formation Fyn Gene Information Basic Information Ensembl ID: ENSMUSG00000019843 Description: Fyn proto-oncogene [Source:MGI Symbol;Acc:MGI:95602] Location: 10:39244851-39441377 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cell surface interactions at the vascular wall Nephrin family interactions Cytokine Signaling in Immune system Hgf Gene Information Basic Information Ensembl ID: ENSMUSG00000028864 Description: hepatocyte growth factor [Source:MGI Symbol;Acc:MGI:96079] Location: 5:16758493-16825150 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell stellate cell eosinophil Other: MAPK family signaling cascades Platelet activation, signaling and aggregation Intracellular signaling by second messengers Igf1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020053 Description: insulin-like growth factor 1 [Source:MGI Symbol;Acc:MGI:96432] Location: 10:87694127-87772904 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell interneuron phagocyte smooth muscle cell epithelial cell stromal cell macrophage dendritic cell Other: Peptide hormone metabolism Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Platelet activation, signaling and aggregation Igf1r Gene Information Basic Information Ensembl ID: ENSMUSG00000005533 Description: insulin-like growth factor I receptor [Source:MGI Symbol;Acc:MGI:96433] Location: 7:67602575-67883416 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell endothelial cell epithelial cell eosinophil mesenchymal cell Other: Signaling by Nuclear Receptors Signaling by Receptor Tyrosine Kinases Igf2 Gene Information Basic Information Ensembl ID: ENSMUSG00000048583 Description: insulin-like growth factor 2 [Source:MGI Symbol;Acc:MGI:96434] Location: 7:142204503-142220553 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stromal cell fibroblast endothelial cell mesothelial cell endocardial cell Other: Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Platelet activation, signaling and aggregation Signaling by Receptor Tyrosine Kinases Insr Gene Information Basic Information Ensembl ID: ENSMUSG00000005534 Description: insulin receptor [Source:MGI Symbol;Acc:MGI:96575] Location: 8:3172061-3329617 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell adrenal cortical cell adipocyte Other: Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Irs2 Gene Information Basic Information Ensembl ID: ENSMUSG00000038894 Description: insulin receptor substrate 2 [Source:MGI Symbol;Acc:MGI:109334] Location: 8:11034681-11058458 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mural cell Other: Cytokine Signaling in Immune system MAPK family signaling cascades Signaling by Erythropoietin Irs4 Gene Information Basic Information Ensembl ID: ENSMUSG00000054667 Description: insulin receptor substrate 4 [Source:MGI Symbol;Acc:MGI:1338009] Location: X:140493994-140508259 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: preadipocyte Other: Signaling by Receptor Tyrosine Kinases Itch Gene Information Basic Information Ensembl ID: ENSMUSG00000027598 Description: itchy%2C E3 ubiquitin protein ligase [Source:MGI Symbol;Acc:MGI:1202301] Location: 2:154975429-155068775 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Signaling by NOTCH Innate Immune System Kdr Gene Information Basic Information Ensembl ID: ENSMUSG00000062960 Description: kinase insert domain protein receptor [Source:MGI Symbol;Acc:MGI:96683] Location: 5:76093487-76139118 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell glial cell Other: Signaling by Receptor Tyrosine Kinases Kit Gene Information Basic Information Ensembl ID: ENSMUSG00000005672 Description: KIT proto-oncogene receptor tyrosine kinase [Source:MGI Symbol;Acc:MGI:96677] Location: 5:75735576-75817382 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell natural killer cell interneuron epithelial cell intercalated cell tuft cell mast cell innate lymphoid cell hematopoietic stem cell progenitor cell dendritic cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Kitl Gene Information Basic Information Ensembl ID: ENSMUSG00000019966 Description: kit ligand [Source:MGI Symbol;Acc:MGI:96974] Location: 10:99851492-99936278 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stromal cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Kl Gene Information Basic Information Ensembl ID: ENSMUSG00000058488 Description: klotho [Source:MGI Symbol;Acc:MGI:1101771] Location: 5:150876072-150917282 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Met Gene Information Basic Information Ensembl ID: ENSMUSG00000009376 Description: met proto-oncogene [Source:MGI Symbol;Acc:MGI:96969] Location: 6:17463799-17573979 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell intercalated cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Nrp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025810 Description: neuropilin 1 [Source:MGI Symbol;Acc:MGI:106206] Location: 8:129085085-129229844 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell Other: Signaling by Receptor Tyrosine Kinases Nervous system development Nrp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000025969 Description: neuropilin 2 [Source:MGI Symbol;Acc:MGI:1100492] Location: 1:62742444-62857854 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell bone cell motor neuron osteoblast macrophage dentate gyrus granule cell Other: Signaling by Receptor Tyrosine Kinases Ntrk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028072 Description: neurotrophic tyrosine kinase%2C receptor%2C type 1 [Source:MGI Symbol;Acc:MGI:97383] Location: 3:87685551-87702469 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast Other: Signaling by Receptor Tyrosine Kinases Ntrk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000059146 Description: neurotrophic tyrosine kinase%2C receptor%2C type 3 [Source:MGI Symbol;Acc:MGI:97385] Location: 7:77825707-78387760 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Protein-protein interactions at synapses Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Pcsk6 Gene Information Basic Information Ensembl ID: ENSMUSG00000030513 Description: proprotein convertase subtilisin/kexin type 6 [Source:MGI Symbol;Acc:MGI:102897] Location: 7:65511482-65700134 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell epithelial cell fibroblast neuron retina cell mesenchymal cell Other: Plasma lipoprotein assembly, remodeling, and clearance Cell junction organization Signaling by Receptor Tyrosine Kinases Pdgfd Gene Information Basic Information Ensembl ID: ENSMUSG00000032006 Description: platelet-derived growth factor%2C D polypeptide [Source:MGI Symbol;Acc:MGI:1919035] Location: 9:6168584-6378850 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell endothelial cell theca cell Other: Signaling by Receptor Tyrosine Kinases Pdgfra Gene Information Basic Information Ensembl ID: ENSMUSG00000029231 Description: platelet derived growth factor receptor%2C alpha polypeptide [Source:MGI Symbol;Acc:MGI:97530] Location: 5:75312953-75358876 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast stellate cell embryonic cell stromal cell astrocyte oligodendrocyte precursor cell oligodendrocyte mesenchymal cell telocyte extracellular matrix producing cell progenitor cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Pdgfrb Gene Information Basic Information Ensembl ID: ENSMUSG00000024620 Description: platelet derived growth factor receptor%2C beta polypeptide [Source:MGI Symbol;Acc:MGI:97531] Location: 18:61178222-61218133 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stellate cell mural cell mesenchymal cell mesangial cell Other: MAPK family signaling cascades Intracellular signaling by second messengers Signaling by Receptor Tyrosine Kinases Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Prkcb Gene Information Basic Information Ensembl ID: ENSMUSG00000052889 Description: protein kinase C%2C beta [Source:MGI Symbol;Acc:MGI:97596] Location: 7:121887974-122233625 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron dendritic cell developing T cell Naive B cell monocyte mast cell Other: Transmission across Chemical Synapses Adaptive Immune System Signaling by WNT Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system Prkce Gene Information Basic Information Ensembl ID: ENSMUSG00000045038 Description: protein kinase C%2C epsilon [Source:MGI Symbol;Acc:MGI:97599] Location: 17:86475213-86965347 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by GPCR Platelet activation, signaling and aggregation Psen1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019969 Description: presenilin 1 [Source:MGI Symbol;Acc:MGI:1202717] Location: 12:83734926-83781973 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by NOTCH Death Receptor Signaling Ptk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000059456 Description: PTK2 protein tyrosine kinase 2 beta [Source:MGI Symbol;Acc:MGI:104908] Location: 14:66390706-66518501 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell Specialized T cell neuron Other: Cytokine Signaling in Immune system Signal regulatory protein family interactions Signaling by Receptor Tyrosine Kinases Ptpn11 Gene Information Basic Information Ensembl ID: ENSMUSG00000043733 Description: protein tyrosine phosphatase%2C non-receptor type 11 [Source:MGI Symbol;Acc:MGI:99511] Location: 5:121268596-121329460 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Nervous system development Cytokine Signaling in Immune system Adaptive Immune System Rap1a Gene Information Basic Information Ensembl ID: ENSMUSG00000068798 Description: RAS-related protein 1a [Source:MGI Symbol;Acc:MGI:97852] Location: 3:105634583-105708652 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell monocyte muscle cell dendritic cell plasma cell megakaryocyte Other: Adaptive Immune System Integration of energy metabolism Innate Immune System Rps6ka1 Gene Information Basic Information Ensembl ID: ENSMUSG00000003644 Description: ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:104558] Location: 4:133574601-133615108 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Innate Immune System Spp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000029304 Description: secreted phosphoprotein 1 [Source:MGI Symbol;Acc:MGI:98389] Location: 5:104582984-104588916 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte glial cell epithelial cell fibroblast hepatocyte Other: Signaling by Receptor Tyrosine Kinases Degradation of the extracellular matrix Integrin cell surface interactions Stat3 Gene Information Basic Information Ensembl ID: ENSMUSG00000004040 Description: signal transducer and activator of transcription 3 [Source:MGI Symbol;Acc:MGI:103038] Location: 11:100775924-100830366 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Signaling by Non-Receptor Tyrosine Kinases Signaling by Receptor Tyrosine Kinases Vegfa Gene Information Basic Information Ensembl ID: ENSMUSG00000023951 Description: vascular endothelial growth factor A [Source:MGI Symbol;Acc:MGI:103178] Location: 17:46327919-46343295 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stellate cell mast cell stromal cell Other: Platelet activation, signaling and aggregation Signaling by Receptor Tyrosine Kinases Vegfc Gene Information Basic Information Ensembl ID: ENSMUSG00000031520 Description: vascular endothelial growth factor C [Source:MGI Symbol;Acc:MGI:109124] Location: 8:54530641-54640131 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Platelet activation, signaling and aggregation Signaling by Receptor Tyrosine Kinases
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Pathway Hierarchies & Genes RHOBTB2 GTPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RHOBTB GTPase Cycle RHOBTB2 GTPase cycle 1 genes RAC1 GTPase cycle (5 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RAC1 GTPase cycle 5 genes RAC2 GTPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RAC2 GTPase cycle 1 genes RHO GTPases Activate Formins (4 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases Activate Formins 4 genes RHO GTPases Activate NADPH Oxidases (3 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases Activate NADPH Oxidases 3 genes RHO GTPases Activate WASPs and WAVEs (3 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases Activate WASPs and WAVEs 3 genes RHO GTPases activate CIT (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases activate CIT 1 genes RHO GTPases activate IQGAPs (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases activate IQGAPs 1 genes RHO GTPases activate KTN1 (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases activate KTN1 1 genes RHO GTPases activate PAKs (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases activate PAKs 1 genes RHO GTPases regulate CFTR trafficking (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase Effectors RHO GTPases regulate CFTR trafficking 1 genes RHOA GTPase cycle (4 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RHOA GTPase cycle 4 genes RHOD GTPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RHOD GTPase cycle 1 genes RHOF GTPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RHOF GTPase cycle 1 genes RHOQ GTPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RHOQ GTPase cycle 1 genes RHOU GTPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RHOU GTPase cycle 1 genes RND1 GTPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RND1 GTPase cycle 1 genes RND3 GTPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Signaling by Rho GTPases RHO GTPase cycle RND3 GTPase cycle 1 genes RHOBTB3 ATPase cycle (1 genes) Signal Transduction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 RHOBTB3 ATPase cycle 1 genes	Arhgap15 Gene Information Basic Information Ensembl ID: ENSMUSG00000049744 Description: Rho GTPase activating protein 15 [Source:MGI Symbol;Acc:MGI:1923367] Location: 2:43638836-44285965 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell developing T cell phagocyte basophil retina cell T cell Other: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Arhgap25 Gene Information Basic Information Ensembl ID: ENSMUSG00000030047 Description: Rho GTPase activating protein 25 [Source:MGI Symbol;Acc:MGI:2443687] Location: 6:87435527-87510241 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: microglia Other: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Arhgap28 Gene Information Basic Information Ensembl ID: ENSMUSG00000024043 Description: Rho GTPase activating protein 28 [Source:MGI Symbol;Acc:MGI:2147003] Location: 17:68149708-68311115 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Arhgap29 Gene Information Basic Information Ensembl ID: ENSMUSG00000039831 Description: Rho GTPase activating protein 29 [Source:MGI Symbol;Acc:MGI:2443818] Location: 3:121746190-121810402 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell pericyte stromal cell epithelial cell Other: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Arhgef7 Gene Information Basic Information Ensembl ID: ENSMUSG00000031511 Description: Rho guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1860493] Location: 8:11777721-11885219 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell smooth muscle cell Other: Signaling by GPCR Death Receptor Signaling Signaling by Receptor Tyrosine Kinases Baiap2 Gene Information Basic Information Ensembl ID: ENSMUSG00000025372 Description: brain-specific angiogenesis inhibitor 1-associated protein 2 [Source:MGI Symbol;Acc:MGI:2137336] Location: 11:119833589-119897608 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Innate Immune System Signaling by Receptor Tyrosine Kinases Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Baiap2l2 Gene Information Basic Information Ensembl ID: ENSMUSG00000018126 Description: BAI1-associated protein 2-like 2 [Source:MGI Symbol;Acc:MGI:2652819] Location: 15:79142395-79169737 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell endocrine cell Other: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Cenpe Gene Information Basic Information Ensembl ID: ENSMUSG00000045328 Description: centromere protein E [Source:MGI Symbol;Acc:MGI:1098230] Location: 3:134918298-134979372 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Cell Cycle, Mitotic Cftr Gene Information Basic Information Ensembl ID: ENSMUSG00000041301 Description: cystic fibrosis transmembrane conductance regulator [Source:MGI Symbol;Acc:MGI:88388] Location: 6:18170686-18322767 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pneumocyte ionocyte Other: Macroautophagy Membrane Trafficking ABC-family proteins mediated transport Chn2 Gene Information Basic Information Ensembl ID: ENSMUSG00000004633 Description: chimerin 2 [Source:MGI Symbol;Acc:MGI:1917243] Location: 6:54016539-54278795 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: blood cell neuron tuft cell mast cell epithelial cell Other: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Cpne8 Gene Information Basic Information Ensembl ID: ENSMUSG00000052560 Description: copine VIII [Source:MGI Symbol;Acc:MGI:1914121] Location: 15:90371685-90563635 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Daam1 Gene Information Basic Information Ensembl ID: ENSMUSG00000034574 Description: dishevelled associated activator of morphogenesis 1 [Source:MGI Symbol;Acc:MGI:1914596] Location: 12:71877852-72039107 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: megakaryocyte Other: Signaling by WNT Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Dlg4 Gene Information Basic Information Ensembl ID: ENSMUSG00000020886 Description: discs large MAGUK scaffold protein 4 [Source:MGI Symbol;Acc:MGI:1277959] Location: 11:69907768-69938348 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Transmission across Chemical Synapses LGI-ADAM interactions MAPK family signaling cascades Dock5 Gene Information Basic Information Ensembl ID: ENSMUSG00000044447 Description: dedicator of cytokinesis 5 [Source:MGI Symbol;Acc:MGI:2652871] Location: 14:67989584-68170891 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell fibroblast stromal cell bone cell Other: Factors involved in megakaryocyte development and platelet production Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Dsg2 Gene Information Basic Information Ensembl ID: ENSMUSG00000044393 Description: desmoglein 2 [Source:MGI Symbol;Acc:MGI:1196466] Location: 18:20691131-20737578 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell tuft cell epithelial cell Other: Apoptosis Keratinization Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Dync1li2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035770 Description: dynein%2C cytoplasmic 1 light intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107738] Location: 8:105144312-105169679 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Adaptive Immune System Macroautophagy Membrane Trafficking Gja1 Gene Information Basic Information Ensembl ID: ENSMUSG00000050953 Description: gap junction protein%2C alpha 1 [Source:MGI Symbol;Acc:MGI:95713] Location: 10:56253426-56278609 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: astrocyte Other: Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Htr7 Gene Information Basic Information Ensembl ID: ENSMUSG00000024798 Description: 5-hydroxytryptamine (serotonin) receptor 7 [Source:MGI Symbol;Acc:MGI:99841] Location: 19:35936134-36034907 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Kif5a Gene Information Basic Information Ensembl ID: ENSMUSG00000074657 Description: kinesin family member 5A [Source:MGI Symbol;Acc:MGI:109564] Location: 10:127061565-127099217 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Adaptive Immune System Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk14 Gene Information Basic Information Ensembl ID: ENSMUSG00000053436 Description: mitogen-activated protein kinase 14 [Source:MGI Symbol;Acc:MGI:1346865] Location: 17:28910303-28967380 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Innate Immune System Cellular responses to stress Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Myh11 Gene Information Basic Information Ensembl ID: ENSMUSG00000018830 Description: myosin%2C heavy polypeptide 11%2C smooth muscle [Source:MGI Symbol;Acc:MGI:102643] Location: 16:14012399-14109236 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte endothelial cell smooth muscle cell fibroblast mural cell mesangial cell Other: Smooth Muscle Contraction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Myo6 Gene Information Basic Information Ensembl ID: ENSMUSG00000033577 Description: myosin VI [Source:MGI Symbol;Acc:MGI:104785] Location: 9:80072313-80219011 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell enteroendocrine cell glial cell astrocyte hair cell Other: Transmission across Chemical Synapses Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Ngef Gene Information Basic Information Ensembl ID: ENSMUSG00000026259 Description: neuronal guanine nucleotide exchange factor [Source:MGI Symbol;Acc:MGI:1858414] Location: 1:87404556-87501592 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by GPCR Death Receptor Signaling Nervous system development Pik3ca Gene Information Basic Information Ensembl ID: ENSMUSG00000027665 Description: phosphatidylinositol-4%2C5-bisphosphate 3-kinase catalytic subunit alpha [Source:MGI Symbol;Acc:MGI:1206581] Location: 3:32451820-32522635 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Innate Immune System Prkcb Gene Information Basic Information Ensembl ID: ENSMUSG00000052889 Description: protein kinase C%2C beta [Source:MGI Symbol;Acc:MGI:97596] Location: 7:121887974-122233625 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron dendritic cell developing T cell Naive B cell monocyte mast cell Other: Transmission across Chemical Synapses Adaptive Immune System Signaling by WNT Prkcd Gene Information Basic Information Ensembl ID: ENSMUSG00000021948 Description: protein kinase C%2C delta [Source:MGI Symbol;Acc:MGI:97598] Location: 14:30317311-30348167 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Intracellular signaling by second messengers Apoptosis Cytokine Signaling in Immune system Ptk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000059456 Description: PTK2 protein tyrosine kinase 2 beta [Source:MGI Symbol;Acc:MGI:104908] Location: 14:66390706-66518501 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: developing T cell Specialized T cell neuron Other: Cytokine Signaling in Immune system Signal regulatory protein family interactions Signaling by Receptor Tyrosine Kinases Ranbp2 Gene Information Basic Information Ensembl ID: ENSMUSG00000003226 Description: RAN binding protein 2 [Source:MGI Symbol;Acc:MGI:894323] Location: 10:58282742-58330178 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Metabolism of non-coding RNA Gene Silencing by RNA Cellular responses to stress Rasal2 Gene Information Basic Information Ensembl ID: ENSMUSG00000070565 Description: RAS protein activator like 2 [Source:MGI Symbol;Acc:MGI:2443881] Location: 1:156962752-157240165 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell glial cell smooth muscle cell neuron Other: MAPK family signaling cascades Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Stmn2 Gene Information Basic Information Ensembl ID: ENSMUSG00000027500 Description: stathmin-like 2 [Source:MGI Symbol;Acc:MGI:98241] Location: 3:8574420-8626666 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell neuron motor neuron retina cell Other: Signaling by Rho GTPases, Miro GTPases and RHOBTB3
Signaling by TGFB family members Pathway Hierarchies & Genes TGFBR3 regulates TGF-beta signaling (2 genes) Signal Transduction Signaling by TGFB family members Signaling by TGF-beta Receptor Complex TGF-beta receptor signaling activates SMADs Downregulation of TGF-beta receptor signaling Signaling by TGFBR3 TGFBR3 regulates TGF-beta signaling 2 genes Downregulation of SMAD2/3:SMAD4 transcriptional activity (3 genes) Signal Transduction Signaling by TGFB family members Signaling by Activin 1 genes Signaling by TGF-beta Receptor Complex Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Downregulation of SMAD2/3:SMAD4 transcriptional activity 2 genes Downregulation of SMAD2/3:SMAD4 transcriptional activity (2 genes) Signal Transduction Signaling by TGFB family members Signaling by TGF-beta Receptor Complex Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer Downregulation of SMAD2/3:SMAD4 transcriptional activity 2 genes TGF-beta receptor signaling activates SMADs (2 genes) Signal Transduction Signaling by TGFB family members Signaling by TGF-beta Receptor Complex TGF-beta receptor signaling activates SMADs 2 genes TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (1 genes) Signal Transduction Signaling by TGFB family members Signaling by TGF-beta Receptor Complex TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) 1 genes TGFBR3 PTM regulation (2 genes) Signal Transduction Signaling by TGFB family members Signaling by TGFBR3 TGFBR3 PTM regulation 2 genes Signaling by BMP (1 genes) Signal Transduction Signaling by TGFB family members Signaling by BMP 1 genes	Acvr1c Gene Information Basic Information Ensembl ID: ENSMUSG00000026834 Description: activin A receptor%2C type IC [Source:MGI Symbol;Acc:MGI:2661081] Location: 2:58157465-58247907 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: preadipocyte stromal cell adipocyte Other: Signaling by TGFB family members Bmpr1b Gene Information Basic Information Ensembl ID: ENSMUSG00000052430 Description: bone morphogenetic protein receptor%2C type 1B [Source:MGI Symbol;Acc:MGI:107191] Location: 3:141542897-141875186 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell astrocyte Other: Signaling by TGFB family members Itga8 Gene Information Basic Information Ensembl ID: ENSMUSG00000026768 Description: integrin alpha 8 [Source:MGI Symbol;Acc:MGI:109442] Location: 2:12111443-12306733 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast smooth muscle cell epithelial cell mesenchymal stem cell Other: Elastic fibre formation Integrin cell surface interactions ECM proteoglycans Ltbp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001870 Description: latent transforming growth factor beta binding protein 1 [Source:MGI Symbol;Acc:MGI:109151] Location: 17:75312563-75699507 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Elastic fibre formation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein modification Mapk1 Gene Information Basic Information Ensembl ID: ENSMUSG00000063358 Description: mitogen-activated protein kinase 1 [Source:MGI Symbol;Acc:MGI:1346858] Location: 16:16801246-16865317 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mapk3 Gene Information Basic Information Ensembl ID: ENSMUSG00000063065 Description: mitogen-activated protein kinase 3 [Source:MGI Symbol;Acc:MGI:1346859] Location: 7:126358773-126364991 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Apoptosis Signaling by NODAL Cytokine Signaling in Immune system Mmp14 Gene Information Basic Information Ensembl ID: ENSMUSG00000000957 Description: matrix metallopeptidase 14 (membrane-inserted) [Source:MGI Symbol;Acc:MGI:101900] Location: 14:54669069-54682821 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast bone cell smooth muscle cell epithelial cell Other: Degradation of the extracellular matrix Signaling by TGFB family members Nedd4l Gene Information Basic Information Ensembl ID: ENSMUSG00000024589 Description: neural precursor cell expressed%2C developmentally down-regulated gene 4-like [Source:MGI Symbol;Acc:MGI:1933754] Location: 18:65020776-65350899 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Adaptive Immune System RNA Polymerase II Transcription Signaling by TGFB family members Pard3 Gene Information Basic Information Ensembl ID: ENSMUSG00000025812 Description: par-3 family cell polarity regulator [Source:MGI Symbol;Acc:MGI:2135608] Location: 8:127790643-128338767 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell motor neuron Other: Cell junction organization Signaling by TGFB family members Psen1 Gene Information Basic Information Ensembl ID: ENSMUSG00000019969 Description: presenilin 1 [Source:MGI Symbol;Acc:MGI:1202717] Location: 12:83734926-83781973 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Innate Immune System Signaling by NOTCH Death Receptor Signaling Skil Gene Information Basic Information Ensembl ID: ENSMUSG00000027660 Description: SKI-like [Source:MGI Symbol;Acc:MGI:106203] Location: 3:31149207-31176726 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: RNA Polymerase II Transcription Signaling by TGFB family members Tgfb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000002603 Description: transforming growth factor%2C beta 1 [Source:MGI Symbol;Acc:MGI:98725] Location: 7:25386427-25404502 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell hematopoietic stem cell phagocyte monocyte leukocyte megakaryocyte Other: Cell surface interactions at the vascular wall Non-integrin membrane-ECM interactions Elastic fibre formation Tgfbr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000032440 Description: transforming growth factor%2C beta receptor II [Source:MGI Symbol;Acc:MGI:98729] Location: 9:115913361-116004428 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast Other: Signaling by TGFB family members
Signaling by WNT Pathway Hierarchies & Genes Ca2+ pathway (1 genes) Signal Transduction Signaling by WNT Degradation of beta-catenin by the destruction complex Beta-catenin phosphorylation cascade TCF dependent signaling in response to WNT Formation of the beta-catenin:TCF transactivating complex Beta-catenin independent WNT signaling Ca2+ pathway 1 genes Ca2+ pathway (3 genes) Signal Transduction Signaling by WNT Degradation of beta-catenin by the destruction complex Repression of WNT target genes TCF dependent signaling in response to WNT Formation of the beta-catenin:TCF transactivating complex 1 genes Beta-catenin independent WNT signaling Ca2+ pathway 2 genes Asymmetric localization of PCP proteins (5 genes) Signal Transduction Signaling by WNT TCF dependent signaling in response to WNT Regulation of FZD by ubiquitination 4 genes Beta-catenin independent WNT signaling PCP/CE pathway Asymmetric localization of PCP proteins 1 genes Asymmetric localization of PCP proteins (1 genes) Signal Transduction Signaling by WNT TCF dependent signaling in response to WNT Disassembly of the destruction complex and recruitment of AXIN to the membrane Beta-catenin independent WNT signaling PCP/CE pathway Asymmetric localization of PCP proteins 1 genes Asymmetric localization of PCP proteins (2 genes) Signal Transduction Signaling by WNT Beta-catenin independent WNT signaling PCP/CE pathway Asymmetric localization of PCP proteins 2 genes WNT5A-dependent internalization of FZD2, FZD5 and ROR2 (1 genes) Signal Transduction Signaling by WNT Beta-catenin independent WNT signaling PCP/CE pathway WNT5A-dependent internalization of FZD2, FZD5 and ROR2 1 genes WNT5A-dependent internalization of FZD4 (2 genes) Signal Transduction Signaling by WNT Beta-catenin independent WNT signaling PCP/CE pathway WNT5A-dependent internalization of FZD4 2 genes Ca2+ pathway (4 genes) Signal Transduction Signaling by WNT Beta-catenin independent WNT signaling Ca2+ pathway 4 genes Deactivation of the beta-catenin transactivating complex (3 genes) Signal Transduction Signaling by WNT TCF dependent signaling in response to WNT Deactivation of the beta-catenin transactivating complex 3 genes PCP/CE pathway (1 genes) Signal Transduction Signaling by WNT Beta-catenin independent WNT signaling PCP/CE pathway 1 genes WNT ligand biogenesis and trafficking (2 genes) Signal Transduction Signaling by WNT WNT ligand biogenesis and trafficking 2 genes	Akt1 Gene Information Basic Information Ensembl ID: ENSMUSG00000001729 Description: thymoma viral proto-oncogene 1 [Source:MGI Symbol;Acc:MGI:87986] Location: 12:112620255-112641318 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Cytokine Signaling in Immune system Adaptive Immune System Signaling by NOTCH Camk2a Gene Information Basic Information Ensembl ID: ENSMUSG00000024617 Description: calcium/calmodulin-dependent protein kinase II alpha [Source:MGI Symbol;Acc:MGI:88256] Location: 18:61058690-61121224 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Signaling by WNT Ctnnb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000006932 Description: catenin beta 1 [Source:MGI Symbol;Acc:MGI:88276] Location: 9:120758282-120789573 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell stem cell epithelial cell Other: Apoptosis Innate Immune System Signaling by WNT Daam1 Gene Information Basic Information Ensembl ID: ENSMUSG00000034574 Description: dishevelled associated activator of morphogenesis 1 [Source:MGI Symbol;Acc:MGI:1914596] Location: 12:71877852-72039107 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: megakaryocyte Other: Signaling by WNT Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Fzd1 Gene Information Basic Information Ensembl ID: ENSMUSG00000044674 Description: frizzled class receptor 1 [Source:MGI Symbol;Acc:MGI:1196625] Location: 5:4803839-4808035 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by WNT Fzd3 Gene Information Basic Information Ensembl ID: ENSMUSG00000007989 Description: frizzled class receptor 3 [Source:MGI Symbol;Acc:MGI:108476] Location: 14:65429898-65499912 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by WNT Fzd7 Gene Information Basic Information Ensembl ID: ENSMUSG00000041075 Description: frizzled class receptor 7 [Source:MGI Symbol;Acc:MGI:108570] Location: 1:59521583-59526114 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by WNT Fzd8 Gene Information Basic Information Ensembl ID: ENSMUSG00000036904 Description: frizzled class receptor 8 [Source:MGI Symbol;Acc:MGI:108460] Location: 18:9212163-9218136 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by WNT Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Lef1 Gene Information Basic Information Ensembl ID: ENSMUSG00000027985 Description: lymphoid enhancer binding factor 1 [Source:MGI Symbol;Acc:MGI:96770] Location: 3:130904120-131018005 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell developing T cell lymphoid progenitor cell Specialized T cell melanocyte CD8+ T cell memory T cell Other: Signaling by WNT RNA Polymerase II Transcription MITF-M-regulated melanocyte development Lgr5 Gene Information Basic Information Ensembl ID: ENSMUSG00000020140 Description: leucine rich repeat containing G protein coupled receptor 5 [Source:MGI Symbol;Acc:MGI:1341817] Location: 10:115286216-115423685 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: fibroblast progenitor cell stem cell epithelial cell stromal cell Other: Signaling by WNT Pde6b Gene Information Basic Information Ensembl ID: ENSMUSG00000029491 Description: phosphodiesterase 6B%2C cGMP%2C rod receptor%2C beta polypeptide [Source:MGI Symbol;Acc:MGI:97525] Location: 5:108536257-108580263 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Signaling by WNT Visual phototransduction Plcb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000051177 Description: phospholipase C%2C beta 1 [Source:MGI Symbol;Acc:MGI:97613] Location: 2:134627987-135317178 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell epithelial cell endothelial cell adipocyte Other: Transmission across Chemical Synapses Inositol phosphate metabolism Integration of energy metabolism Prkcb Gene Information Basic Information Ensembl ID: ENSMUSG00000052889 Description: protein kinase C%2C beta [Source:MGI Symbol;Acc:MGI:97596] Location: 7:121887974-122233625 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron dendritic cell developing T cell Naive B cell monocyte mast cell Other: Transmission across Chemical Synapses Adaptive Immune System Signaling by WNT Prkcg Gene Information Basic Information Ensembl ID: ENSMUSG00000078816 Description: protein kinase C%2C gamma [Source:MGI Symbol;Acc:MGI:97597] Location: 7:3337704-3379615 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Signaling by WNT Signaling by GPCR Ror1 Gene Information Basic Information Ensembl ID: ENSMUSG00000035305 Description: receptor tyrosine kinase-like orphan receptor 1 [Source:MGI Symbol;Acc:MGI:1347520] Location: 4:99952988-100301962 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stem cell stromal cell motor neuron mural cell Other: Signaling by WNT Rspo1 Gene Information Basic Information Ensembl ID: ENSMUSG00000028871 Description: R-spondin 1 [Source:MGI Symbol;Acc:MGI:2183426] Location: 4:124880223-124902892 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell Other: Signaling by WNT Rspo2 Gene Information Basic Information Ensembl ID: ENSMUSG00000051920 Description: R-spondin 2 [Source:MGI Symbol;Acc:MGI:1922667] Location: 15:42884190-43034222 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Signaling by WNT Rspo3 Gene Information Basic Information Ensembl ID: ENSMUSG00000019880 Description: R-spondin 3 [Source:MGI Symbol;Acc:MGI:1920030] Location: 10:29328412-29411863 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell Other: Signaling by WNT Sox6 Gene Information Basic Information Ensembl ID: ENSMUSG00000051910 Description: SRY (sex determining region Y)-box 6 [Source:MGI Symbol;Acc:MGI:98368] Location: 7:115070107-115638031 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: skeletal muscle cell glial cell oligodendrocyte precursor cell epithelial cell chondrocyte Other: Signaling by WNT Sox9 Gene Information Basic Information Ensembl ID: ENSMUSG00000000567 Description: SRY (sex determining region Y)-box 9 [Source:MGI Symbol;Acc:MGI:98371] Location: 11:112673050-112678586 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stromal cell tuft cell muscle cell chondrocyte bone cell progenitor cell hepatocyte natural killer cell stem cell Other: Signaling by WNT RNA Polymerase II Transcription Tcf7l2 Gene Information Basic Information Ensembl ID: ENSMUSG00000024985 Description: transcription factor 7 like 2%2C T cell specific%2C HMG box [Source:MGI Symbol;Acc:MGI:1202879] Location: 19:55730252-55922086 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell fibroblast macrophage excitatory neuron mesenchymal cell oligodendrocyte Other: Signaling by WNT RNA Polymerase II Transcription MITF-M-regulated melanocyte development Tle4 Gene Information Basic Information Ensembl ID: ENSMUSG00000024642 Description: transducin-like enhancer of split 4 [Source:MGI Symbol;Acc:MGI:104633] Location: 19:14425514-14575415 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell excitatory neuron Other: Signaling by WNT Wls Gene Information Basic Information Ensembl ID: ENSMUSG00000028173 Description: wntless WNT ligand secretion mediator [Source:MGI Symbol;Acc:MGI:1915401] Location: 3:159545309-159644300 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell stem cell pneumocyte stromal cell retinal pigment epithelial cell Other: Signaling by WNT Wnt7b Gene Information Basic Information Ensembl ID: ENSMUSG00000022382 Description: wingless-type MMTV integration site family%2C member 7B [Source:MGI Symbol;Acc:MGI:98962] Location: 15:85419638-85466674 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: progenitor cell stem cell epithelial cell Other: Signaling by WNT
Smooth Muscle Contraction Pathway Hierarchies & Genes Smooth Muscle Contraction (4 genes) Muscle contraction Smooth Muscle Contraction 4 genes	Acta2 Gene Information Basic Information Ensembl ID: ENSMUSG00000035783 Description: actin alpha 2%2C smooth muscle%2C aorta [Source:MGI Symbol;Acc:MGI:87909] Location: 19:34218490-34232990 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte stellate cell endothelial cell stem cell smooth muscle cell fibroblast mural cell mesangial cell progenitor cell muscle cell mesenchymal cell Other: Non-integrin membrane-ECM interactions Smooth Muscle Contraction Cell junction organization Lmod1 Gene Information Basic Information Ensembl ID: ENSMUSG00000048096 Description: leiomodin 1 (smooth muscle) [Source:MGI Symbol;Acc:MGI:2135671] Location: 1:135252545-135295803 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell fibroblast mural cell mesangial cell Other: Smooth Muscle Contraction Myh11 Gene Information Basic Information Ensembl ID: ENSMUSG00000018830 Description: myosin%2C heavy polypeptide 11%2C smooth muscle [Source:MGI Symbol;Acc:MGI:102643] Location: 16:14012399-14109236 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: pericyte endothelial cell smooth muscle cell fibroblast mural cell mesangial cell Other: Smooth Muscle Contraction Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Sorbs1 Gene Information Basic Information Ensembl ID: ENSMUSG00000025006 Description: sorbin and SH3 domain containing 1 [Source:MGI Symbol;Acc:MGI:700014] Location: 19:40283197-40502223 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: glial cell smooth muscle cell skeletal muscle cell mesangial cell adipocyte Other: Smooth Muscle Contraction
Surfactant metabolism Pathway Hierarchies & Genes Surfactant metabolism (4 genes) Metabolism of proteins Surfactant metabolism 4 genes	Adgrf5 Gene Information Basic Information Ensembl ID: ENSMUSG00000056492 Description: adhesion G protein-coupled receptor F5 [Source:MGI Symbol;Acc:MGI:2182928] Location: 17:43671342-43770448 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell Other: Surfactant metabolism Adora2a Gene Information Basic Information Ensembl ID: ENSMUSG00000020178 Description: adenosine A2a receptor [Source:MGI Symbol;Acc:MGI:99402] Location: 10:75152711-75170618 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Signaling by GPCR Surfactant metabolism Adora2b Gene Information Basic Information Ensembl ID: ENSMUSG00000018500 Description: adenosine A2b receptor [Source:MGI Symbol;Acc:MGI:99403] Location: 11:62139810-62157279 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: eosinophil Other: Signaling by GPCR Surfactant metabolism Adra2c Gene Information Basic Information Ensembl ID: ENSMUSG00000045318 Description: adrenergic receptor%2C alpha 2c [Source:MGI Symbol;Acc:MGI:87936] Location: 5:35435663-35439107 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Integration of energy metabolism Signaling by GPCR Surfactant metabolism
Synthesis of DNA Pathway Hierarchies & Genes Orc1 removal from chromatin (1 genes) DNA Replication Synthesis of DNA Switching of origins to a post-replicative state Orc1 removal from chromatin 1 genes	Mcm6 Gene Information Basic Information Ensembl ID: ENSMUSG00000026355 Description: minichromosome maintenance complex component 6 [Source:MGI Symbol;Acc:MGI:1298227] Location: 1:128259327-128287401 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: erythroblast Other: DNA Replication Pre-Initiation Synthesis of DNA Cell Cycle, Mitotic
Transcriptional regulation of granulopoiesis Pathway Hierarchies & Genes Transcriptional regulation of granulopoiesis (1 genes) Developmental Biology Transcriptional regulation of granulopoiesis 1 genes	Cdkn1a Gene Information Basic Information Ensembl ID: ENSMUSG00000023067 Description: cyclin dependent kinase inhibitor 1A [Source:MGI Symbol;Acc:MGI:104556] Location: 17:29309950-29319701 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endothelial cell fibroblast muscle cell smooth muscle cell schwann cell monocyte epithelial cell Other: Cellular responses to stress Cell Cycle, Mitotic Cell Cycle Checkpoints
Translation Pathway Hierarchies & Genes Mitochondrial translation elongation (1 genes) Metabolism of proteins Translation Mitochondrial translation Mitochondrial translation elongation 1 genes	Mrpl16 Gene Information Basic Information Ensembl ID: ENSMUSG00000024683 Description: mitochondrial ribosomal protein L16 [Source:MGI Symbol;Acc:MGI:2137219] Location: 19:11747755-11752324 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Translation
Transmission across Chemical Synapses Pathway Hierarchies & Genes Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits (7 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission GABA receptor activation GABA B receptor activation Activation of GABAB receptors Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits 7 genes RSK activation (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Activation of NMDA receptors and postsynaptic events Post NMDA receptor activation events CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling RSK activation 1 genes Activation of Ca-permeable Kainate Receptor (2 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Activation of kainate receptors upon glutamate binding Ionotropic activity of kainate receptors Activation of Ca-permeable Kainate Receptor 2 genes Activation of GABAB receptors (4 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission GABA receptor activation GABA B receptor activation Activation of GABAB receptors 4 genes Activation of Na-permeable kainate receptors (2 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Activation of kainate receptors upon glutamate binding Ionotropic activity of kainate receptors Activation of Na-permeable kainate receptors 2 genes Highly calcium permeable postsynaptic nicotinic acetylcholine receptors (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Acetylcholine binding and downstream events Postsynaptic nicotinic acetylcholine receptors Highly calcium permeable postsynaptic nicotinic acetylcholine receptors 1 genes Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Acetylcholine binding and downstream events Presynaptic nicotinic acetylcholine receptors Highly sodium permeable postsynaptic acetylcholine nicotinic receptors 1 genes Trafficking of GluR2-containing AMPA receptors (5 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Glutamate binding, activation of AMPA receptors and synaptic plasticity Trafficking of AMPA receptors Trafficking of GluR2-containing AMPA receptors 5 genes Assembly and cell surface presentation of NMDA receptors (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Activation of NMDA receptors and postsynaptic events Assembly and cell surface presentation of NMDA receptors 1 genes Presynaptic function of Kainate receptors (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Activation of kainate receptors upon glutamate binding Presynaptic function of Kainate receptors 1 genes Reuptake of GABA (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter release cycle GABA synthesis, release, reuptake and degradation Reuptake of GABA 1 genes Trafficking of AMPA receptors (6 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Glutamate binding, activation of AMPA receptors and synaptic plasticity Trafficking of AMPA receptors 6 genes Unblocking of NMDA receptors, glutamate binding and activation (3 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission Activation of NMDA receptors and postsynaptic events Unblocking of NMDA receptors, glutamate binding and activation 3 genes Acetylcholine Neurotransmitter Release Cycle (2 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter release cycle Acetylcholine Neurotransmitter Release Cycle 2 genes Astrocytic Glutamate-Glutamine Uptake And Metabolism (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter uptake and metabolism In glial cells Astrocytic Glutamate-Glutamine Uptake And Metabolism 1 genes Dopamine Neurotransmitter Release Cycle (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter release cycle Dopamine Neurotransmitter Release Cycle 1 genes Dopamine clearance from the synaptic cleft (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter clearance Dopamine clearance from the synaptic cleft 1 genes GABA receptor activation (7 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission GABA receptor activation 7 genes GABA synthesis, release, reuptake and degradation (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter release cycle GABA synthesis, release, reuptake and degradation 1 genes Glutamate Neurotransmitter Release Cycle (3 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter release cycle Glutamate Neurotransmitter Release Cycle 3 genes Serotonin Neurotransmitter Release Cycle (10 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter release cycle Serotonin Neurotransmitter Release Cycle 10 genes Serotonin clearance from the synaptic cleft (1 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter clearance Serotonin clearance from the synaptic cleft 1 genes Neurotransmitter receptors and postsynaptic signal transmission (3 genes) Neuronal System Transmission across Chemical Synapses Neurotransmitter receptors and postsynaptic signal transmission 3 genes Presynaptic depolarization and calcium channel opening (4 genes) Neuronal System Transmission across Chemical Synapses Presynaptic depolarization and calcium channel opening 4 genes	Adcy1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020431 Description: adenylate cyclase 1 [Source:MGI Symbol;Acc:MGI:99677] Location: 11:7013489-7128506 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell neuron Other: Transmission across Chemical Synapses Signaling by GPCR Signaling by Hedgehog Adcy2 Gene Information Basic Information Ensembl ID: ENSMUSG00000021536 Description: adenylate cyclase 2 [Source:MGI Symbol;Acc:MGI:99676] Location: 13:68768162-69147660 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell skeletal muscle cell excitatory neuron Other: Transmission across Chemical Synapses Signaling by GPCR Signaling by Hedgehog Adcy5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022840 Description: adenylate cyclase 5 [Source:MGI Symbol;Acc:MGI:99673] Location: 16:34975247-35126108 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: smooth muscle cell projection neuron Other: Transmission across Chemical Synapses Integration of energy metabolism Signaling by GPCR Apba1 Gene Information Basic Information Ensembl ID: ENSMUSG00000024897 Description: amyloid beta precursor protein binding family A member 1 [Source:MGI Symbol;Acc:MGI:1860297] Location: 19:23736251-23926960 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron antigen presenting cell interneuron monocyte Other: Transmission across Chemical Synapses Cacna1a Gene Information Basic Information Ensembl ID: ENSMUSG00000034656 Description: calcium channel%2C voltage-dependent%2C P/Q type%2C alpha 1A subunit [Source:MGI Symbol;Acc:MGI:109482] Location: 8:85065268-85366875 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron endocrine cell interneuron Other: Transmission across Chemical Synapses Integration of energy metabolism Cacna1b Gene Information Basic Information Ensembl ID: ENSMUSG00000004113 Description: calcium channel%2C voltage-dependent%2C N type%2C alpha 1B subunit [Source:MGI Symbol;Acc:MGI:88296] Location: 2:24493899-24653164 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Cacna1e Gene Information Basic Information Ensembl ID: ENSMUSG00000004110 Description: calcium channel%2C voltage-dependent%2C R type%2C alpha 1E subunit [Source:MGI Symbol;Acc:MGI:106217] Location: 1:154266477-154760247 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell excitatory neuron Other: Transmission across Chemical Synapses Integration of energy metabolism Cacna2d3 Gene Information Basic Information Ensembl ID: ENSMUSG00000021991 Description: calcium channel%2C voltage-dependent%2C alpha2/delta subunit 3 [Source:MGI Symbol;Acc:MGI:1338890] Location: 14:28626900-29443821 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron Other: Transmission across Chemical Synapses Cacng3 Gene Information Basic Information Ensembl ID: ENSMUSG00000066189 Description: calcium channel%2C voltage-dependent%2C gamma subunit 3 [Source:MGI Symbol;Acc:MGI:1859165] Location: 7:122269715-122368616 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron retina cell Other: Transmission across Chemical Synapses LGI-ADAM interactions Camk2a Gene Information Basic Information Ensembl ID: ENSMUSG00000024617 Description: calcium/calmodulin-dependent protein kinase II alpha [Source:MGI Symbol;Acc:MGI:88256] Location: 18:61058690-61121224 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Signaling by WNT Camk2b Gene Information Basic Information Ensembl ID: ENSMUSG00000057897 Description: calcium/calmodulin-dependent protein kinase II%2C beta [Source:MGI Symbol;Acc:MGI:88257] Location: 11:5919644-6016362 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: kidney cell neuron enteroendocrine cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2d Gene Information Basic Information Ensembl ID: ENSMUSG00000053819 Description: calcium/calmodulin-dependent protein kinase II%2C delta [Source:MGI Symbol;Acc:MGI:1341265] Location: 3:126389951-126639975 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Naive B cell glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Camk2g Gene Information Basic Information Ensembl ID: ENSMUSG00000021820 Description: calcium/calmodulin-dependent protein kinase II gamma [Source:MGI Symbol;Acc:MGI:88259] Location: 14:20784943-20844156 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Cellular responses to stress Chat Gene Information Basic Information Ensembl ID: ENSMUSG00000021919 Description: choline O-acetyltransferase [Source:MGI Symbol;Acc:MGI:88392] Location: 14:32130160-32187946 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: tuft cell motor neuron Other: Transmission across Chemical Synapses Metabolism of lipids Chrna4 Gene Information Basic Information Ensembl ID: ENSMUSG00000027577 Description: cholinergic receptor%2C nicotinic%2C alpha polypeptide 4 [Source:MGI Symbol;Acc:MGI:87888] Location: 2:180660173-180685339 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Chrnb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000031492 Description: cholinergic receptor%2C nicotinic%2C beta polypeptide 3 [Source:MGI Symbol;Acc:MGI:106212] Location: 8:27858739-27889758 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Cplx1 Gene Information Basic Information Ensembl ID: ENSMUSG00000033615 Description: complexin 1 [Source:MGI Symbol;Acc:MGI:104727] Location: 5:108666420-108697890 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron Other: Transmission across Chemical Synapses Dlg4 Gene Information Basic Information Ensembl ID: ENSMUSG00000020886 Description: discs large MAGUK scaffold protein 4 [Source:MGI Symbol;Acc:MGI:1277959] Location: 11:69907768-69938348 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Transmission across Chemical Synapses LGI-ADAM interactions MAPK family signaling cascades Gabbr2 Gene Information Basic Information Ensembl ID: ENSMUSG00000039809 Description: gamma-aminobutyric acid type B receptor subunit 2 [Source:MGI Symbol;Acc:MGI:2386030] Location: 4:46662305-46991873 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron sensory neuron Other: Transmission across Chemical Synapses Potassium Channels Signaling by GPCR Gabra2 Gene Information Basic Information Ensembl ID: ENSMUSG00000000560 Description: gamma-aminobutyric acid type A receptor subunit alpha 2 [Source:MGI Symbol;Acc:MGI:95614] Location: 5:71114940-71253192 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell interneuron excitatory neuron Other: Transmission across Chemical Synapses Gabra5 Gene Information Basic Information Ensembl ID: ENSMUSG00000055078 Description: gamma-aminobutyric acid type A receptor subunit alpha 5 [Source:MGI Symbol;Acc:MGI:95617] Location: 7:57057420-57159807 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Gabra6 Gene Information Basic Information Ensembl ID: ENSMUSG00000020428 Description: gamma-aminobutyric acid type A receptor subunit alpha 6 [Source:MGI Symbol;Acc:MGI:95618] Location: 11:42197264-42211899 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron granule cell Other: Transmission across Chemical Synapses Gabrb2 Gene Information Basic Information Ensembl ID: ENSMUSG00000007653 Description: gamma-aminobutyric acid type A receptor subunit beta 2 [Source:MGI Symbol;Acc:MGI:95620] Location: 11:42310584-42519855 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Gabrb3 Gene Information Basic Information Ensembl ID: ENSMUSG00000033676 Description: GABRB3%2C gamma-aminobutyric acid type A receptor subunit beta 3 [Source:MGI Symbol;Acc:MGI:95621] Location: 7:57069440-57478550 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Gabrg3 Gene Information Basic Information Ensembl ID: ENSMUSG00000055026 Description: gamma-aminobutyric acid type A receptor%2C subunit gamma 3 [Source:MGI Symbol;Acc:MGI:95624] Location: 7:56366213-57036936 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron epithelial cell Other: Transmission across Chemical Synapses Gabrq Gene Information Basic Information Ensembl ID: ENSMUSG00000031344 Description: gamma-aminobutyric acid type A receptor subunit theta [Source:MGI Symbol;Acc:MGI:1888498] Location: X:71868784-71886208 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Glra2 Gene Information Basic Information Ensembl ID: ENSMUSG00000018589 Description: glycine receptor%2C alpha 2 subunit [Source:MGI Symbol;Acc:MGI:95748] Location: X:163912013-164110389 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Glra3 Gene Information Basic Information Ensembl ID: ENSMUSG00000038257 Description: glycine receptor%2C alpha 3 subunit [Source:MGI Symbol;Acc:MGI:95749] Location: 8:56393495-56583105 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Gls Gene Information Basic Information Ensembl ID: ENSMUSG00000026103 Description: glutaminase [Source:MGI Symbol;Acc:MGI:95752] Location: 1:52202607-52272391 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Metabolism of amino acids and derivatives RNA Polymerase II Transcription Gls2 Gene Information Basic Information Ensembl ID: ENSMUSG00000044005 Description: glutaminase 2 (liver%2C mitochondrial) [Source:MGI Symbol;Acc:MGI:2143539] Location: 10:128030326-128045873 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Metabolism of amino acids and derivatives RNA Polymerase II Transcription Gnal Gene Information Basic Information Ensembl ID: ENSMUSG00000024524 Description: guanine nucleotide binding protein%2C alpha stimulating%2C olfactory type [Source:MGI Symbol;Acc:MGI:95774] Location: 18:67221287-67359863 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Signaling by GPCR Olfactory Signaling Pathway Gng7 Gene Information Basic Information Ensembl ID: ENSMUSG00000048240 Description: guanine nucleotide binding protein (G protein)%2C gamma 7 [Source:MGI Symbol;Acc:MGI:95787] Location: 10:80784458-80850779 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: projection neuron Other: Transmission across Chemical Synapses Potassium Channels Integration of energy metabolism Gria1 Gene Information Basic Information Ensembl ID: ENSMUSG00000020524 Description: glutamate receptor%2C ionotropic%2C AMPA1 (alpha 1) [Source:MGI Symbol;Acc:MGI:95808] Location: 11:56902213-57221070 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell neuron Other: Transmission across Chemical Synapses Membrane Trafficking Post-translational protein modification Gria3 Gene Information Basic Information Ensembl ID: ENSMUSG00000001986 Description: glutamate receptor%2C ionotropic%2C AMPA3 (alpha 3) [Source:MGI Symbol;Acc:MGI:95810] Location: X:40489731-40767478 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: Regulatory T cell epithelial cell inhibitory neuron projection neuron Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Gria4 Gene Information Basic Information Ensembl ID: ENSMUSG00000025892 Description: glutamate receptor%2C ionotropic%2C AMPA4 (alpha 4) [Source:MGI Symbol;Acc:MGI:95811] Location: 9:4417896-4796234 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell neuron interneuron Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Grik1 Gene Information Basic Information Ensembl ID: ENSMUSG00000022935 Description: glutamate receptor%2C ionotropic%2C kainate 1 [Source:MGI Symbol;Acc:MGI:95814] Location: 16:87692788-88087153 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron oligodendrocyte precursor cell Other: Transmission across Chemical Synapses Grik2 Gene Information Basic Information Ensembl ID: ENSMUSG00000056073 Description: glutamate receptor%2C ionotropic%2C kainate 2 (beta 2) [Source:MGI Symbol;Acc:MGI:95815] Location: 10:48970929-49664862 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron glial cell mast cell inhibitory neuron Other: Transmission across Chemical Synapses Grik3 Gene Information Basic Information Ensembl ID: ENSMUSG00000001985 Description: glutamate receptor%2C ionotropic%2C kainate 3 [Source:MGI Symbol;Acc:MGI:95816] Location: 4:125384493-125607966 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron excitatory neuron Other: Transmission across Chemical Synapses Grin1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026959 Description: glutamate receptor%2C ionotropic%2C NMDA1 (zeta 1) [Source:MGI Symbol;Acc:MGI:95819] Location: 2:25181193-25209199 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses MAPK family signaling cascades Protein-protein interactions at synapses Grin2a Gene Information Basic Information Ensembl ID: ENSMUSG00000059003 Description: glutamate receptor%2C ionotropic%2C NMDA2A (epsilon 1) [Source:MGI Symbol;Acc:MGI:95820] Location: 16:9385762-9813424 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Grin2c Gene Information Basic Information Ensembl ID: ENSMUSG00000020734 Description: glutamate receptor%2C ionotropic%2C NMDA2C (epsilon 3) [Source:MGI Symbol;Acc:MGI:95822] Location: 11:115139995-115158069 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Grin3a Gene Information Basic Information Ensembl ID: ENSMUSG00000039579 Description: glutamate receptor ionotropic%2C NMDA3A [Source:MGI Symbol;Acc:MGI:1933206] Location: 4:49661611-49845744 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron oligodendrocyte precursor cell Other: Transmission across Chemical Synapses Htr3a Gene Information Basic Information Ensembl ID: ENSMUSG00000032269 Description: 5-hydroxytryptamine (serotonin) receptor 3A [Source:MGI Symbol;Acc:MGI:96282] Location: 9:48810513-48822399 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Kcnj10 Gene Information Basic Information Ensembl ID: ENSMUSG00000044708 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 10 [Source:MGI Symbol;Acc:MGI:1194504] Location: 1:172168777-172201652 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell glial cell Other: Transmission across Chemical Synapses Potassium Channels Kcnj2 Gene Information Basic Information Ensembl ID: ENSMUSG00000041695 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 2 [Source:MGI Symbol;Acc:MGI:104744] Location: 11:110956990-110967647 (+) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Potassium Channels Cardiac conduction Kcnj3 Gene Information Basic Information Ensembl ID: ENSMUSG00000026824 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 3 [Source:MGI Symbol;Acc:MGI:104742] Location: 2:55325982-55488157 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell neuron cardiomyocyte retina cell Other: Transmission across Chemical Synapses Potassium Channels Kcnj4 Gene Information Basic Information Ensembl ID: ENSMUSG00000044216 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 4 [Source:MGI Symbol;Acc:MGI:104743] Location: 15:79367915-79389442 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Potassium Channels Cardiac conduction Kcnj5 Gene Information Basic Information Ensembl ID: ENSMUSG00000032034 Description: potassium inwardly-rectifying channel%2C subfamily J%2C member 5 [Source:MGI Symbol;Acc:MGI:104755] Location: 9:32226003-32255646 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Potassium Channels Myo6 Gene Information Basic Information Ensembl ID: ENSMUSG00000033577 Description: myosin VI [Source:MGI Symbol;Acc:MGI:104785] Location: 9:80072313-80219011 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell enteroendocrine cell glial cell astrocyte hair cell Other: Transmission across Chemical Synapses Membrane Trafficking Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Plcb1 Gene Information Basic Information Ensembl ID: ENSMUSG00000051177 Description: phospholipase C%2C beta 1 [Source:MGI Symbol;Acc:MGI:97613] Location: 2:134627987-135317178 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: bergmann glial cell epithelial cell endothelial cell adipocyte Other: Transmission across Chemical Synapses Inositol phosphate metabolism Integration of energy metabolism Ppfia2 Gene Information Basic Information Ensembl ID: ENSMUSG00000053825 Description: protein tyrosine phosphatase%2C receptor type%2C f polypeptide (PTPRF)%2C interacting protein (liprin)%2C alpha 2 [Source:MGI Symbol;Acc:MGI:2443834] Location: 10:106306200-106771813 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron pericyte Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Ppfia4 Gene Information Basic Information Ensembl ID: ENSMUSG00000026458 Description: protein tyrosine phosphatase%2C receptor type%2C f polypeptide (PTPRF)%2C interacting protein (liprin)%2C alpha 4 [Source:MGI Symbol;Acc:MGI:1915757] Location: 1:134224521-134260666 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Protein-protein interactions at synapses Prkcb Gene Information Basic Information Ensembl ID: ENSMUSG00000052889 Description: protein kinase C%2C beta [Source:MGI Symbol;Acc:MGI:97596] Location: 7:121887974-122233625 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron dendritic cell developing T cell Naive B cell monocyte mast cell Other: Transmission across Chemical Synapses Adaptive Immune System Signaling by WNT Prkcg Gene Information Basic Information Ensembl ID: ENSMUSG00000078816 Description: protein kinase C%2C gamma [Source:MGI Symbol;Acc:MGI:97597] Location: 7:3337704-3379615 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Signaling by WNT Signaling by GPCR Rab3a Gene Information Basic Information Ensembl ID: ENSMUSG00000031840 Description: RAB3A%2C member RAS oncogene family [Source:MGI Symbol;Acc:MGI:97843] Location: 8:71207328-71211323 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Innate Immune System Membrane Trafficking Rps6ka1 Gene Information Basic Information Ensembl ID: ENSMUSG00000003644 Description: ribosomal protein S6 kinase polypeptide 1 [Source:MGI Symbol;Acc:MGI:104558] Location: 4:133574601-133615108 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: dendritic cell myeloid progenitor cell Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system Innate Immune System Slc17a7 Gene Information Basic Information Ensembl ID: ENSMUSG00000070570 Description: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter)%2C member 7 [Source:MGI Symbol;Acc:MGI:1920211] Location: 7:44813373-44825566 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron excitatory neuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc18a2 Gene Information Basic Information Ensembl ID: ENSMUSG00000025094 Description: solute carrier family 18 (vesicular monoamine)%2C member 2 [Source:MGI Symbol;Acc:MGI:106677] Location: 19:59249328-59284444 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mast cell modulatory neuron neuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc32a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000037771 Description: solute carrier family 32 (GABA vesicular transporter)%2C member 1 [Source:MGI Symbol;Acc:MGI:1194488] Location: 2:158452687-158457668 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: interneuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc38a1 Gene Information Basic Information Ensembl ID: ENSMUSG00000023169 Description: solute carrier family 38%2C member 1 [Source:MGI Symbol;Acc:MGI:2145895] Location: 15:96469299-96540794 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell dendritic cell Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc5a7 Gene Information Basic Information Ensembl ID: ENSMUSG00000023945 Description: solute carrier family 5 (choline transporter)%2C member 7 [Source:MGI Symbol;Acc:MGI:1927126] Location: 17:54580618-54606062 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: motor neuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc6a11 Gene Information Basic Information Ensembl ID: ENSMUSG00000030307 Description: solute carrier family 6 (neurotransmitter transporter%2C GABA)%2C member 11 [Source:MGI Symbol;Acc:MGI:95630] Location: 6:114108202-114226913 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell astrocyte Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Metabolism of amino acids and derivatives Slc6a3 Gene Information Basic Information Ensembl ID: ENSMUSG00000021609 Description: solute carrier family 6 (neurotransmitter transporter%2C dopamine)%2C member 3 [Source:MGI Symbol;Acc:MGI:94862] Location: 13:73684866-73726791 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: modulatory neuron Other: Transmission across Chemical Synapses SLC-mediated transmembrane transport Slc6a4 Gene Information Basic Information Ensembl ID: ENSMUSG00000020838 Description: solute carrier family 6 (neurotransmitter transporter%2C serotonin)%2C member 4 [Source:MGI Symbol;Acc:MGI:96285] Location: 11:76889429-76923166 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: mast cell Other: Transmission across Chemical Synapses Stx1a Gene Information Basic Information Ensembl ID: ENSMUSG00000007207 Description: syntaxin 1A (brain) [Source:MGI Symbol;Acc:MGI:109355] Location: 5:135052336-135079954 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: excitatory neuron Other: Transmission across Chemical Synapses Cytokine Signaling in Immune system LGI-ADAM interactions Stxbp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000026797 Description: syntaxin binding protein 1 [Source:MGI Symbol;Acc:MGI:107363] Location: 2:32677614-32737257 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses Syn1 Gene Information Basic Information Ensembl ID: ENSMUSG00000037217 Description: synapsin I [Source:MGI Symbol;Acc:MGI:98460] Location: X:20726750-20787243 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron Other: Transmission across Chemical Synapses Syn2 Gene Information Basic Information Ensembl ID: ENSMUSG00000009394 Description: synapsin II [Source:MGI Symbol;Acc:MGI:103020] Location: 6:115111863-115258967 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: neuron kidney cell intercalated cell Other: Transmission across Chemical Synapses Syn3 Gene Information Basic Information Ensembl ID: ENSMUSG00000059602 Description: synapsin III [Source:MGI Symbol;Acc:MGI:1351334] Location: 10:85890989-86334760 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Transmission across Chemical Synapses
Visual phototransduction Pathway Hierarchies & Genes Activation of the phototransduction cascade (1 genes) Sensory Perception Visual phototransduction The phototransduction cascade Activation of the phototransduction cascade 1 genes Inactivation, recovery and regulation of the phototransduction cascade (2 genes) Sensory Perception Visual phototransduction The phototransduction cascade Inactivation, recovery and regulation of the phototransduction cascade 2 genes Retinoid metabolism and transport (1 genes) Sensory Perception Visual phototransduction The canonical retinoid cycle in rods (twilight vision) Retinoid metabolism and transport 1 genes The canonical retinoid cycle in rods (twilight vision) (1 genes) Sensory Perception Visual phototransduction The retinoid cycle in cones (daylight vision) The canonical retinoid cycle in rods (twilight vision) 1 genes Retinoid metabolism and transport (3 genes) Sensory Perception Visual phototransduction Retinoid metabolism and transport 3 genes	Gpc3 Gene Information Basic Information Ensembl ID: ENSMUSG00000055653 Description: glypican 3 [Source:MGI Symbol;Acc:MGI:104903] Location: X:51361303-51702827 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: stellate cell stromal cell embryonic cell fibroblast epithelial cell Other: Metabolism of vitamins and cofactors Visual phototransduction Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Gpc5 Gene Information Basic Information Ensembl ID: ENSMUSG00000022112 Description: glypican 5 [Source:MGI Symbol;Acc:MGI:1194894] Location: 14:115329647-116762591 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell oligodendrocyte precursor cell Other: Metabolism of vitamins and cofactors Visual phototransduction Signaling by Hedgehog Lpl Gene Information Basic Information Ensembl ID: ENSMUSG00000015568 Description: lipoprotein lipase [Source:MGI Symbol;Acc:MGI:96820] Location: 8:69333143-69360100 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: preadipocyte phagocyte fibroblast epithelial cell stromal cell erythrocyte dendritic cell macrophage endothelial cell antigen presenting cell adipocyte Other: Plasma lipoprotein assembly, remodeling, and clearance Metabolism of vitamins and cofactors Visual phototransduction Pde6b Gene Information Basic Information Ensembl ID: ENSMUSG00000029491 Description: phosphodiesterase 6B%2C cGMP%2C rod receptor%2C beta polypeptide [Source:MGI Symbol;Acc:MGI:97525] Location: 5:108536257-108580263 (+) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: photoreceptor cell Other: Signaling by WNT Visual phototransduction Rbp4 Gene Information Basic Information Ensembl ID: ENSMUSG00000024990 Description: retinol binding protein 4%2C plasma [Source:MGI Symbol;Acc:MGI:97879] Location: 19:38105077-38113729 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell stromal cell epithelial cell enteroendocrine cell hepatocyte Other: Metabolism of vitamins and cofactors Visual phototransduction Rgs9 Gene Information Basic Information Ensembl ID: ENSMUSG00000020599 Description: regulator of G-protein signaling 9 [Source:MGI Symbol;Acc:MGI:1338824] Location: 11:109116181-109188955 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: endocrine cell photoreceptor cell projection neuron Other: Visual phototransduction Signaling by GPCR Protein folding Rgs9bp Gene Information Basic Information Ensembl ID: ENSMUSG00000056043 Description: regulator of G-protein signalling 9 binding protein [Source:MGI Symbol;Acc:MGI:2384418] Location: 7:35278418-35285007 (-) Biotype: protein_coding Species: Mus musculus Annotations Other: Visual phototransduction Rlbp1 Gene Information Basic Information Ensembl ID: ENSMUSG00000039194 Description: retinaldehyde binding protein 1 [Source:MGI Symbol;Acc:MGI:97930] Location: 7:79024618-79036796 (-) Biotype: protein_coding Species: Mus musculus Annotations Cell Type Markers: epithelial cell oligodendrocyte precursor cell retinal pigment epithelial cell Other: Visual phototransduction

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